This is an archived course. A more recent version may be available at ocw.mit.edu.
Prof. Douglas Lauffenburger
Prof. Alan Grodzinsky
20.430J / 2.795J / 6.561J / 10.539J / HST.544J
This course covers the following topics: conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and solid continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG. The course also examines electromechanical and physicochemical interactions in biomaterials and cells; orthopaedic, cardiovascular, and other clinical examples.
OCW has published multiple versions of this subject.
Douglas Lauffenburger, and Alan Grodzinsky. 20.430J Fields, Forces, and Flows in Biological Systems (BE.430J). Fall 2004. Massachusetts Institute of Technology: MIT OpenCourseWare, https://ocw.mit.edu. License: Creative Commons BY-NC-SA.