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    • Dysregulated RasGRP1 Responds to Cytokine Receptor Input in T Cell Leukemogenesis 

      Yang, Ming; Govern, Christopher C.; Chakraborty, Arup K.; Hartzell, Catherine; Ksionda, Olga; e.a. (American Association for the Advancement of Science (AAAS), 2013-03)
      Enhanced signaling by the small guanosine triphosphatase Ras is common in T cell acute lymphoblastic leukemia/lymphoma (T-ALL), but the underlying mechanisms are unclear. We identified the guanine nucleotide exchange factor ...