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A quantitative framework for characterizing the evolutionary history of mammalian gene expression
(Cold Spring Harbor Laboratory, 201812)The evolutionary history of a gene helps predict its function and relationship to phenotypic traits. Although sequence conservation is commonly used to decipher gene function and assess medical relevance, methods for ... 
A quantitative framework For largescale model estimation and discrimination In systems biology
(Massachusetts Institute of Technology, 2013)Using models to simulate and analyze biological networks requires principled approaches to parameter estimation and model discrimination. We use Bayesian and Monte Carlo methods to recover the full probability distributions ... 
QUantitative Imaging of eXtraction of oxygen and TIssue consumption (QUIXOTIC) using venulartargeted velocityselective spin labeling
(John Wiley & Sons, Inc, 201112)While oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) are fundamental parameters of brain health and function, a robust MRIbased mapping of OEF and CMRO2 amenable to functional MRI (fMRI) ... 
Quantitative imaging of living cells by deep ultraviolet microscopy
(Massachusetts Institute of Technology, 2006)Developments in light microscopy over the past three centuries have opened new windows into cell structure and function, yet many questions remain unanswered by current imaging approaches. Deep ultraviolet microscopy ... 
Quantitative imaging of the airwater flow fields formed by unsteady breaking waves
(Massachusetts Institute of Technology, 2009)An experimental method for simultaneously measuring the velocity fields on the air and water side of unsteady breaking waves is presented. The method is applied to breaking waves to investigate the physics of the air and ... 
Quantitative Inference in a Mechanical Design Compiler
(19890101)This paper presents the ideas underlying a program that takes as input a schematic of a mechanical or hydraulic power transmission system, plus specifications and a utility function, and returns catalog numbers from ... 
Quantitative Information Flow as Network Flow Capacity
(20071210)We present a new technique for determining how much information abouta program's secret inputs is revealed by its public outputs. Incontrast to previous techniques based on reachability from secretinputs (tainting), it ... 
Quantitative InformationFlow Tracking for C and Related Languages
(20061117)We present a new approach for tracking programs' use of data througharbitrary calculations, to determine how much information about secretinputs is revealed by public outputs. Using a finegrained dynamicbittracking ... 
Quantitative informationflow tracking for real systems
(Massachusetts Institute of Technology, 2008)An informationflow security policy constrains a computer system's endtoend use of information, even as it is transformed in computation. For instance, a policy would not just restrict what secret data could be revealed ... 
Quantitative Interpretation of the Randomness in Single Enzyme Turnover Times
(Elsevier, 201108)Fluctuating turnover times of a single enzyme become observable with the advent of modern cuttingedge, single enzyme experimental techniques. Although the conventional chemical kinetics and its modern generalizations could ... 
Quantitative invertibility of random matrices : a combinatorial perspective
(Massachusetts Institute of Technology, 2020)In this thesis, we develop a novel framework for investigating the lower tail behavior of the least singular value of random matrices  a subject which has been intensely studied in the past two decades. Our focus is on ... 
Quantitative investigation of inlet vortex flow field
(Cambridge, Mass. : Gas Turbine & Plasma Dynamics Laboratory, Massachusetts Institute of Technology, [1984], 1984)A quantitative investigation of the flow field of an inlet in crosswind has been carried out for various operating conditions, including flow regimes representative of aircraft engine inlets at takeoff. The measurements ... 
A quantitative investigation of the imperativeanddeclarative construction in English
(John Hopkins University Press, 201112)The imperativeanddeclarative (IaD) construction in English (e.g. Study hard and you will pass the class) has two distinct readings: one that has the semantics of a conditional and additionally the meaning of an imperative, ... 
Quantitative isoforrm profiling & isoform convergence
(Massachusetts Institute of Technology, 2005)Alternative premessenger RNA splicing is a crucial step in eukaryotic gene expression, and therefore it is subject to tight regulation. Given its importance in conferring protein diversity, alternative splicing is sensitive ... 
Quantitative LabelFree Imaging of 3D Vascular Networks SelfAssembled in Synthetic Hydrogels
(Wiley, 201901)Vascularization is an important strategy to overcome diffusion limits and enable the formation of complex, physiologically relevant engineered tissues and organoids. Selfassembly is a technique to generate in vitro vascular ... 
Quantitative Limiting Absorption Principle in the Semiclassical Limit
(Springer Basel, 201404)We give an elementary proof of Burq’s resolvent bounds for long range semiclassical Schrödinger operators. Globally, the resolvent norm grows exponentially in the inverse semiclassical parameter, and near infinity it grows ... 
Quantitative linkage of physiology and gene expression through empirical model construction: an investigation of diabetes
(200301)A methodology for the construction of predictive empirical models of physiological characteristics from microarray data is presented. The method, applied here to the study of the development of diabetes and insulin resistance, ... 
Quantitative longterm monitoring of the circulating gases in the KATRIN experiment using Raman spectroscopy
(Multidisciplinary Digital Publishing Institute, 202008)The Karlsruhe Tritium Neutrino (KATRIN) experiment aims at measuring the effective electron neutrino mass with a sensitivity of 0.2 eV/c[superscript 2], i.e., improving on previous measurements by an order of magnitude. ... 
Quantitative mass spectrometry analysis of the early signaling dynamics of the epidermal growth factor receptor
(Massachusetts Institute of Technology, 2016)In recent years, the field of systems biology rapidly expanded in both basic and translational science. This method of investigation revolves around an iterative cycle of observing a system, making predictions about its ... 
Quantitative measurement and modeling of the DNA damage signaling network : DNA doublestrand breaks
(Massachusetts Institute of Technology, 2009)DNA doublestrand breaks (DSB) are one of the major mediators of chemotherapyinduced cytotoxicity in tumors. Cells that experience DNA damage can initiate a DNA damagemediated cellcycle arrest, attempt to repair the ...