Browsing by Title
Now showing items 114570-114589 of 114804
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Y B ME? : an analysis of the status of women in mechanical engineering and the Women's Technology Program as a potential long-term solution
(Massachusetts Institute of Technology, 2006)The issue of the lack of women in the fields of science and engineering has recently received new attention by the scientific and women's studies communities alike. In fields such as Mechanical Engineering there continues ... -
Y MAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens
(BioMed Central Ltd, 2014-11)The design of effective antimicrobial therapies for serious eukaryotic pathogens requires a clear understanding of their highly variable genomes. To facilitate analysis of copy number variations, single nucleotide polymorphisms ... -
Y-family DNA polymerases in Escherichia coli
(Elsevier, 2007-01)The observation that mutations in the Escherichia coli genes umuC+ and umuD+ abolish mutagenesis induced by UV light strongly supported the counterintuitive notion that such mutagenesis is an active rather than passive ... -
YabA of Bacillus subtilis controls DnaA-mediated replication initiation but not the transcriptional response to replication stress
(Blackwell Publishing, 2009-09)yabA encodes a negative regulator of replication initiation in Bacillus subtilis and homologues are found in many other Gram-positive species. YabA interacts with the β-processivity clamp (DnaN) of DNA polymerase and with ... -
YAMA : a system for marking network traffic
(Massachusetts Institute of Technology, 2006)Computer security performance analysis requires precise labeling of traffic as either background or attack traffic. When an experiment is performed on-line, it may also be important to identify traffic from the security ... -
Yang-Mills connections with isolated singularities
(Massachusetts Institute of Technology, 2000) -
Yang-Mills replacement
(Massachusetts Institute of Technology, 2016)We develop an analog of the harmonic replacement technique of Colding and Minicozzi in the gauge theory context. The idea behind harmonic replacement dates back to Schwarz and Perron, and the technique involves taking a ... -
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth
(EMBO, 2018-10)The Hippo pathway and its nuclear effector Yap regulate organ size and cancer formation. While many modulators of Hippo activity have been identified, little is known about the Yap target genes that mediate these growth ... -
Yarditecture : new walls for trench town
(Massachusetts Institute of Technology, 2014)"The yard" -- the typical housing typology of low-income downtown, Jamaica where multiple households are contained within a surrounding wall. This thesis envelops itself in Trench town, Jamaica, the epicenter of what is ... -
Yardstick Competition : an empirical investigation using state taxes and media markets
(Massachusetts Institute of Technology, 2014)I investigate whether voters judge the performance of their governor on taxes by comparing him to governors from neighboring states. If voters do make these comparisons, it creates "yardstick competition," where governors ... -
Years of service and probability of promotion
(Cambridge, Mass. : Massachusetts Institute of Technology, 1983]) -
Yeast and mammalian RNA polymerase II holoenzymes
(Massachusetts Institute of Technology, 1997) -
Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase
(American Chemical Society, 2009-10)Escherichia coli lipoic acid ligase (LplA) catalyzes ATP-dependent covalent ligation of lipoic acid onto specific lysine side chains of three acceptor proteins involved in oxidative metabolism. Our lab has shown that LplA ... -
Yeast Golden Gate: Standardized Assembly of S. cerevisiae Transcriptional Units
(2012-10-11)BBF RFC 88 describes a new standard for the assembly of basic Saccharomyces cerevisiae transcriptional units (TUs) consisting of a promoter/5’untranslated region (UTR), open reading frame (ORF), and 3’UTR/terminator. Note ... -
A Yeast Model of FUS/TLS-Dependent Cytotoxicity
(Public Library of Science, 2011-04)FUS/TLS is a nucleic acid binding protein that, when mutated, can cause a subset of familial amyotrophic lateral sclerosis (fALS). Although FUS/TLS is normally located predominantly in the nucleus, the pathogenic mutant ... -
Yeast Reveal a ‘Druggable’ Rsp5/Nedd4 Network That Ameliorates α-Synuclein Toxicity in Neurons
(American Association for the Advancement of Science (AAAS), 2013-10)α-Synuclein (α-syn) is a small lipid-binding protein implicated in several neurodegenerative diseases, including Parkinson’s disease, whose pathobiology is conserved from yeast to man. There are no therapies targeting these ... -
The yeast three-hybrid system : a method for detecting ligand-protein interactions
(Massachusetts Institute of Technology, 1996) -
Yeast-based vaccine approaches to cancer immunotherapy
(Massachusetts Institute of Technology, 2008)Saccharomyces cerevisiae stimulates dendritic cells and represents a promising candidate for cancer immunotherapy development. Effective cross-presentation of antigen delivered to dendritic cells is necessary for successful ... -
Yellow helmets : work and worth of women workers on construction sites in northern India
(Massachusetts Institute of Technology, 2000)The participation of women in the building sector is an exception rather than a rule. Inmost countries of the world the building industry is almost exclusively the domain of men. In India a large number of women are actively ... -
The Yellow Pages : a medium, an industry
(Massachusetts Institute of Technology, 1984)
