http://hdl.handle.net/1721.1/33976 Biological Engineering (BE) http://hdl.handle.net/1721.1/36892 BE.462J Molecular Principles of Biomaterials, Spring 2003 Irvine, Darrell J. Analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, biosensors, and cell-guiding surfaces. http://hdl.handle.net/1721.1/36885 BE.442 Molecular Structure of Biological Materials, Fall 2005 Zhang, Shuguang, Dr. Basic molecular structural principles of biological materials. Molecular structures of various materials of biological origin, including collagen, silk, bone, protein adhesives, GFP, self-assembling peptides. Molecular design of new biological materials for nanotechnology, biocomputing and regenerative medicine. Graduate students are expected to complete additional coursework. Description from course home page: This course, intended for both graduate and upper level undergraduate students, will focus on understanding of the basic molecular structural principles of biological materials. It will address the molecular structures of various materials of biological origin, such as several types of collagen, silk, spider silk, wool, hair, bones, shells, protein adhesives, GFP, and self-assembling peptides. It will also address molecular design of new biological materials applying the molecular structural principles. The long-term goal of this course is to teach molecular design of new biological materials for a broad range of applications. A brief history of biological materials and its future perspective as well as its impact to the society will also be discussed. Several experts will be invited to give guest lectures. http://hdl.handle.net/1721.1/36883 6.021J / 2.791J / 2.794J / 6.521J / BE.370J / BE.470J / HST.541J Quantitative Physiology: Cells and Tissues, Fall 2002 Freeman, Dennis M. Weiss, Thomas Fischer Poe, Mya Principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Mass transport through membranes: diffusion, osmosis, chemically mediated, and active transport. Electric properties of cells: ion transport; equilibrium, resting, and action potentials. Kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the concepts. For juniors and seniors. Students engage in extensive written and oral communication exercises. Meets with graduate subject 6.521J, but assignments differ. http://hdl.handle.net/1721.1/36882 BE.430J Fields, Forces, and Flows in Biological Systems, Fall 2004 Grodzinsky, Alan J. Lauffenburger, Douglas A. This course covers the following topics: conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and solid continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG. The course also examines electromechanical and physicochemical interactions in biomaterials and cells; orthopaedic, cardiovascular, and other clinical examples.