http://hdl.handle.net/1721.1/7789 2013-05-24T22:28:38Z http://hdl.handle.net/1721.1/77762 Studies in the revulcanization of reclaim rubber Roboff, Stanley B Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1943.; MIT copy bound with: The use of scrap leather for artificial leather soles / Alfred B. Babcock, Jr. and William R. Kittredge. 1943.; Includes bibliographical references (leaves 20-21). 1943-01-01T00:00:00Z http://hdl.handle.net/1721.1/74871 Laminar free convection heat transfer in a vertical channel with linear wall temperatures Stefany, Nelson E; Fricke, Paul H Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1961.; MIT copy bound with: Transient responses in gaseous fractionation by adsorption - analogue computer study / Donald D. Easson. 1961.; Includes bibliographical references (leaves 48-49). 1961-01-01T00:00:00Z http://hdl.handle.net/1721.1/73388 Palladium-catalyzed C-N cross-coupling reactions toward the synthesis of drug-like molecules McAvoy, Camille Z The development of methodologies for C-N bond formation reactions is an important scientific challenge because of many academic and industrial applications. This work will focus particularly on palladium-catalyzed cross-couplings of amine-containing compounds with aryl halides. The scope of the BrettPhos precatalyst for the cross-coupling of ortho-substituted aryl iodides with amides is studied using substrates with a variety of functional groups. Due to potential metal-chelating issues with some of the substrates used in this study, a proposed ligand synthesis is discussed in which one of the methoxy groups of BrettPhos is replaced with a morpholine capable of occupying palladium's open coordination site during its catalytic cycle. A final C-N bond formation study focuses on the cross-coupling of aryl halides with amidine salts. For this cross-coupling, a methodology has been developed that can be applied to various electron-rich, electron-poor, and electron-neutral substrates. Furthermore, the products of this cross-coupling can be used for a subsequent electrocyclization through a reaction with aldehyde, demonstrating that a relatively simple two-pot methodology can be used to make relatively complex substrates with pharmaceutical applications. Both amides and amidines are common moieties in drug-like molecules because of the various biological activities of these functional groups. Potential medicinal applications of the developed cross-coupling of amidine salts with aryl halides methodology are described. Thus, methodologies for various palladium-catalyzed, C-N cross-couplings as well as a potential ligand synthesis to be used for palladium catalysis are herein discussed. Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Chemistry; and, (S.B.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2012.; Cataloged from PDF version of thesis.; Includes bibliographical references (p. ). 2012-01-01T00:00:00Z http://hdl.handle.net/1721.1/72795 The analytical constants of horse, neatsfoot, and tallow oils by Allan Winter Rowe. Rowe, Allan Winter, 1879-1934 Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1901.; MIT copy bound with: A study of the Becchi test for cotton-seed oil / Charles H. Dennison. 1901-01-01T00:00:00Z