http://hdl.handle.net/1721.1/7725 Mon, 20 May 2013 09:34:46 GMT 2013-05-20T09:34:46Z http://hdl.handle.net/1721.1/69811 Influenza : a study of contemporary medical politics Doshi, Peter Nikolai Over the past decade, the prevention and control of seasonal and pandemic influenza has grown to be one of the largest and most visible public health policies. This dissertation considers contemporary influenza policy as a case study in what I call medical politics, in which a disease that for most people is rather unremarkable has become the focus of intense (and costly) public health campaigns based on a shaky scientific basis. The dissertation seeks to explain how this could happen. The first two chapters show how influenza and its pandemics are marketed through an appeal to numerous scientific claims. Drawing on governmental marketing materials, statements by officials, and policy documents, I try to let officials speak for themselves and, as much as possible, refrain from analysis. Chapter 3 tells the story of the 2009 novel influenza H1N1 outbreak, showing how official understandings about influenza were called into question by an outbreak far milder than experts had predicted, and discusses investigations which highlighted the role of industry in shaping influenza policy. Chapter 4 analyzes official scientific claims regarding influenza, and argues that degree to which influenza is a serious public health problem is actually unclear. Furthermore, influenza vaccine effectiveness has been vastly overstated, predictive models of pandemic influenza are demonstrably flawed, and officials conflate true influenza with influenza-like illness (ILl), an often overlooked but critical distinction which allows officials to mislead the public into holding false assumptions about the potential benefits of influenza vaccine. Chapter 5 highlights the centrality of "virus-centric thinking" and the ethic of "saving lives" in public health practice as important factors that help explain how such a situation can exist and persist in light of the evidence. Chapter 6 addresses the policy implications of the dissertation's findings. Thesis (Ph. D. in History, Anthropology, and Science, Technology and Society (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, 2011.; Cataloged from PDF version of thesis.; Includes bibliographical references (p. 271-312). Sat, 01 Jan 2011 05:00:00 GMT http://hdl.handle.net/1721.1/69811 2011-01-01T05:00:00Z http://hdl.handle.net/1721.1/69453 Corporate bodies and chemical bonds : an STS analysis of natural gas development in the United States Wylie, Sara Ann Natural gas extraction in the United States in the early 21st century has transformed social, physical, legal and biological landscapes. The technique of hydraulic fracturing, which entails the high-pressure injection into subsurface shale formations of synthetic chemical mixtures, has been viewed by the natural gas industry as a practice of great promise. But there is another side to the story. The first half of this dissertation explores an innovative scientific approach to studying the possible deleterious impacts on human health and the environment of the release of chemicals used in gas extraction. Via participant-observation within a small scientific advocacy organization, The Endocrine Disruption Exchange (TEDX), I follow the development of a database of chemicals used in natural gas extraction, a database that seeks to document not only what these chemicals are (many are proprietary), but also what sorts of bodily and ecological effects these substances may have. I analyze ethnographically how TEDX transformed an information vacuum around fracturing and generated fierce regional and national debates about the public health effects of this activity. The second portion of the dissertation expands TEDX's databasing methodology by reporting on a set of online user-generated databasing and mapping tools developed to interconnect communities encountering the corporate forces and chemical processes animating gas development. Shale gas extraction is an intensive technological practice and requires the delicate calibration of corporate, governmental, and legal apparatuses in order to proceed. The industry operates at county, state, and federal levels, and has in many instances been able to organize regulatory environments suited to rapid and lucrative gas extraction. In the midst of such multi-scalar deterritorializing forces, communities may have little legal or technical recourse if they think that they have been subject to chemical and corporate forces that undermine their financial, bodily, and social security. ExtrAct, a research group I co-founded and directed with artist and technologist Chris Csikszentmihalyi, sought to intervene in these processes by developing a suite of online mapping and databasing tools through which "gas patch" communities could share information, network, study and respond to industry activity across states. Using ExtrAct as an example this dissertation explores how social sciences and the academy at large can invest in developing research tools, methods, and programs designed for non-corporate ends, perhaps redressing in the process the informational and technical imbalances faced by communities dealing with large-scale multinational industries whose infrastructure and impacts are largely invisible to public scrutiny. The dissertation describes one potential method for such engaged scientific and social scientific research: an iterative, ethnographically informed process that I term "STS in Practice." Thesis (Ph. D. in History, Anthropology, and Science, Technology and Society (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, 2011.; Page 689 blank. Cataloged from PDF version of thesis.; Includes bibliographical references (p. 652-688). Sat, 01 Jan 2011 05:00:00 GMT http://hdl.handle.net/1721.1/69453 2011-01-01T05:00:00Z http://hdl.handle.net/1721.1/69452 The rules of perception : American color science, 1831-1931 Rossi, Michael Paul, Ph. D. Massachusetts Institute of Technology Although vision was seldom studied in Antebellum America, color and color perception became a critical field of scientific inquiry in the United States during the Gilded Age and progressive era. Through a historical investigation of color science in the United States in the late nineteenth and early twentieth centuries, I argue that attempts to scientifically measure, define, and regulate color were part of a wider program to construct a more rational, harmonious, and efficient American polity starting from one of the very baseline perceptual components of reality - the experience of color. As part of this program, I argue secondly that color science was as much a matter of prescription as description - that is, color scientists didn't simply endeavor to reveal the facts of perception and apply them to social problems, they wanted to train everyday citizens to see scientifically, and thereby create citizens whose eyes, bodies, and minds were both medically healthy and morally tuned to the needs of the modern American nation. Finally, I argue not simply that perception has a history - i.e. that perceptual practices change over time, and that, for Americans of a century ago, experiences of color sensations were not taken as given but had to be laboriously crafted - but also that this history weighs heavily upon our present day understanding of visual reality, as manifested not least of all in scientific studies of vision, language, and cognition. Employing a close reading of the archival and published sources of a range of actors including physicist Ogden Rood, semiotician Charles Peirce, logician Christine Ladd-Franklin, board game magnate Milton Bradley, and art professor Alfred Munsell, among others, this study reveals the origins of some of the most deeply-rooted conceptions of color in modern American culture. Thesis (Ph. D. in History, Anthropology, and Science, Technology and Society (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, 2011.; Cataloged from PDF version of thesis.; Includes bibliographical references (p. 365-389). Sat, 01 Jan 2011 05:00:00 GMT http://hdl.handle.net/1721.1/69452 2011-01-01T05:00:00Z http://hdl.handle.net/1721.1/69451 Placing outer space : an earthly ethnography of other worlds Messeri, Lisa Rebecca This dissertation concerns the role of place in scientific practice. Ideas of place, I argue, shape and are shaped by science. I specifically look at the community of planetary scientists who, though they cannot step foot on the objects they study, transform planets into places. This is an ethnographic work that draws on 18 months of fieldwork during which time I encountered several different communities of planetary scientists. At MIT, I worked alongside astronomers looking for planets around other stars. These "exoplanet" astronomers transformed numerical counts of photons into complex worlds with atmospheres and weather. Data visualizations characterized the work of a community learning to see unseen planets in specific, place-based ways. I also traveled with an astronomer to a Chilean observatory where she studied the night sky hoping to find a "habitable planet." Many other astronomers share this goal and have designed various ways to detect a planet like Earth. The importance of these projects signifies that exoplanet astronomers are more interested in finding planetary kin - planets that are familiar places - than exotic aliens. To determine how the planetary places created by exoplanet astronomers differ from those in our own Solar System, I spent time at the NASA Ames Research Center with a group of computer scientists who create high resolution and three-dimensional maps of Mars. These maps reflect the kind of place Mars is today: it is available to everyone to explore, it is displayed such that you can imagine standing on the surface, and it is presented as geologically dynamic in ways similar to Earth. Even though these maps help give Mars a sense of place, Martian science is still stymied by the inability to send humans to its surface. Instead, planetary scientists travel to terrestrial sites deemed to be "Mars-like" to approximate performing geologic fieldwork on Mars. I went to one of these locations to see how, during these outings, Mars and Earth become entwined as scientists forge connections between two planetary places. These diverse scientific activities, I conclude, are transforming our view of the cosmos. Outer space is becoming outer place. Thesis (Ph. D. in History, Anthropology, and Science, Technology and Society (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, 2011.; Cataloged from PDF version of thesis.; Includes bibliographical references (p. 269-283). Sat, 01 Jan 2011 05:00:00 GMT http://hdl.handle.net/1721.1/69451 2011-01-01T05:00:00Z