Coronary Artery Disease and Diabetes Mellitus
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Edelman_Coronary artery.pdf
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1.2 MB
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9d8b25420a89df3e194176a5d204dda1
Author(s)
Aronson, Doron
Edelman, Elazer R.
Date Issued
June 2014
Journal
Cardiology Clinics
Publisher
Elsevier
Citation
Aronson, Doron, and Elazer R. Edelman. “Coronary Artery Disease and Diabetes Mellitus.” Cardiology Clinics 32, no. 3 (August 2014): 439–55.
Version
Author's final manuscript
Abstract
Coronary artery disease (CAD) is a major determinant of the long-term prognosis among patients with diabetes mellitus (DM). DM is associated with a 2 to 4-fold increased mortality risk from heart disease. Furthermore, in patients with DM there is an increased mortality after MI, and worse overall prognosis with CAD. Near-normal glycemic control for a median of 3.5 to 5 years does not reduce cardiovascular events. Thus, the general goal of HbA1c <7% appears reasonable for the majority of patients. Iatrogenic hypoglycemia is the limiting factor in the glycemic management of diabetes, and is an independent cause of excess morbidity and mortality. Statins are effective in reducing major coronary events, stroke, and the need for coronary revascularization.
MIT Department
Institute for Medical Engineering and Science
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.ccl.2014.04.001
