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Intra/extracellular multi-drug delivery for osteoarthritis
(Massachusetts Institute of Technology, 2020)
Osteoarthritis (OA), the most common form of arthritis, affects hundreds of millions of people worldwide and tens of millions of people within the United States. This disease is typically diagnosed only after extensive and ...
Engineering myelination in vitro
(Massachusetts Institute of Technology, 2020)
The brain is the powerhouse of the central nervous system (CNS). When this system is out of balance, the implications are massive: neurological diseases are the leading cause of disability and number two leading cause of ...
Enhancing CO₂ fixation by synergistic substrate cofeeding
(Massachusetts Institute of Technology, 2020)
The irrevocable rise of atmospheric CO₂ levels has prompted the development of scalable carbon fixation technologies in recent years. To this end, biological non-photosynthetic methods serve as promising leads since they ...
Insights into future electric mobility
(Massachusetts Institute of Technology, 2020)
Growing global awareness of the environmental impacts of combustion is accelerating electric vehicles (EVs) adoption. However, future sustainable mobility cannot be achieved without substantial changes in vehicle technology, ...
Protein immobilization using complex coacervates and complex coacervate thin films
(Massachusetts Institute of Technology, 2021)
Enzymes can enable a wide and growing range of chemistries, often outperforming synthetic catalysts. However, enzymes must often be converted to heterogeneous catalysts. Protein immobilization enables this conversion and ...
Mechanistic studies and design of supported transition metal complexes
(Massachusetts Institute of Technology, 2020)
Supported transition metal (TM) complexes are an emerging class of materials with many potential applications in the chemical industry ranging from separations to catalysis. They offer increased tunability and often also ...
Exploring cancer metabolism through isotopic tracing and metabolic flux analysis
(Massachusetts Institute of Technology, 2020)
Cancer is the second leading cause of death following heart diseases in the U.S. During the past two decades, cancer metabolism has emerged as an indispensable part of contemporary cancer research. Various types of metabolic ...
Colloidal Electronics
(Massachusetts Institute of Technology, 2020)
Arming nano-electronics with mobility extends artificial systems into traditionally inaccessible environments. Carbon nanotubes (1D), graphene (2D) and other low-dimensional materials with well-defined lattice structures ...
Towards quantitatively predicting the properties of gels and elastomers
(Massachusetts Institute of Technology, 2021)
Polymer networks are critical to modern society. Applications of polymer networks, in the form of gels and elastomers, provide essential support for everyday life. However, while many aspects of the physics of polymer ...
Layer-by-layer coated microneedles for cancer immunotherapy
(Massachusetts Institute of Technology, 2021)
Over the past few decades, research in therapeutic cancer vaccines has achieved remarkable advances in both pre-clinical and clinical studies. However, strategies to boost antigen presentation and T cell priming in order ...