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Computational approaches to understand the atomistic drivers of enzyme catalysis
(Massachusetts Institute of Technology, 2021)
Enzymes readily perform chemical reactions several orders of magnitude faster than their uncatalyzed versions in ambient conditions with high specificity, making them attractive design targets for industrial purposes. ...
Towards quantitatively predicting the properties of gels and elastomers
(Massachusetts Institute of Technology, 2021)
Polymer networks are critical to modern society. Applications of polymer networks, in the form of gels and elastomers, provide essential support for everyday life. However, while many aspects of the physics of polymer ...
Layer-by-layer coated microneedles for cancer immunotherapy
(Massachusetts Institute of Technology, 2021)
Over the past few decades, research in therapeutic cancer vaccines has achieved remarkable advances in both pre-clinical and clinical studies. However, strategies to boost antigen presentation and T cell priming in order ...
Engineering gas diffusion electrodes for electrochemical carbon dioxide upgrading
(Massachusetts Institute of Technology, 2021)
Electrochemical carbon dioxide reduction (CO2R) is increasingly recognized as a viable technology for the generation of chemicals using carbon dioxide (CO₂) recovered from industrial exhaust streams or directly captured ...
Protein immobilization using complex coacervates and complex coacervate thin films
(Massachusetts Institute of Technology, 2021)
Enzymes can enable a wide and growing range of chemistries, often outperforming synthetic catalysts. However, enzymes must often be converted to heterogeneous catalysts. Protein immobilization enables this conversion and ...
Kinetic analysis of leaching reactions in multi-component mineral systems
(Massachusetts Institute of Technology, 2021)
The rational design of reactive systems requires the use of kinetic models of system behavior. However, the development of such models for multicomponent systems is complicated by conditions of mutual interference in ...