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Combining adaptive and designed statistical experimentation : process improvement, data classification, experimental optimization and model building
(Massachusetts Institute of Technology, 2009)
Research interest in the use of adaptive experimentation has returned recently. This historic technique adapts and learns from each experimental run but requires quick runs and large effects. The basis of this renewed ...
Modeling and control of combustion instability
(Massachusetts Institute of Technology, 2000)
Synthesis and analysis of parallel Kinematic XY flexure mechanisms
(Massachusetts Institute of Technology, 2004)
This thesis presents a family of XY flexure mechanisms with large ranges of motion, first-order decoupled degrees of freedom, and small parasitic error motions. Synthesis is based on an systematic and symmetric layout of ...
Integrated strain actuation in aircraft with highly flexible composite wings
(Massachusetts Institute of Technology, 2003)
The purpose of this thesis is to provide a framework for the study of wing warping as a means of achieving multiple aeroelastic goals. Shape change is achieved by integrating anisotropic piezoelectric composites (APC) ...
Mechanics of abrasive wear of elastomeric materials
(Massachusetts Institute of Technology, 2003)
Elastomeric materials are widely used as tire and sealing materials due to their ability to undergo large deformations and conform to the mating surface. However, their applications often result in repeated contact with ...
A study of loading parameters that affect DNA electrophoresis in microdevices
(Massachusetts Institute of Technology, 2001)
Electrophoresis of DNA has become particularly attractive in today's age of bio-technology. The goal of the present research is to optimize the the gel-loading and sample-loading protocols used prior to electrophoresis ...
Optimal capacity adjustment for supply chain control
(Massachusetts Institute of Technology, 2004)
This research attempts to answer the questions involving the time and size of capacity adjustments for better supply chain management. The objective of this research is to analytically determine simple structures to adjust ...
Physics and learning based computational models for breaking bow waves based on new boundary immersion approaches
(Massachusetts Institute of Technology, 2008)
A ship moving on the free surface produces energetic breaking bow waves which generate spray and air entrainment. Present experimental, analytic, and numerical studies of this problem are costly, inaccurate and not robust. ...
Cell-matrix interactions : collagen-GAG scaffold fabrication, characterization, and measurement of cell migratory and contractile behavior via confocal microscopy
(Massachusetts Institute of Technology, 2006)
Three-dimensional, collagen scaffolds are an analog of the extracellular matrix and are used for many tissue engineering applications. While material and microstructural properties significantly affect overall scaffold ...
Molecular mechanics of cartilage : quantification of GAG electrostatic interactions via high-resolution force spectroscopy
(Massachusetts Institute of Technology, 2003)
Intermolecular repulsion forces between negatively charged glycosaminoglycan (CS-GAG) macromolecules are a major determinant of cartilage biomechanical properties. It is thought that the electrostatic component of the total ...