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Now showing items 3931-3940 of 4054
Diels-Alder reactions of organotin acetylides and the chemistry of the adducts
(Massachusetts Institute of Technology, 1966)
Measuring the absolute concentration of particles in suspension using high frequency B-mode ultrasound imaging
(Massachusetts Institute of Technology, 2016)
Concentration measurement of particles in suspension is an important procedure performed in biological and clinical laboratories. Existing methods based on instruments such as hemocytometers, coulter counters, and flow ...
Scalable algorithms for semi-automatic segmentation of electron microscopy images of the brain tissue
(Massachusetts Institute of Technology, 2016)
I present a set of fast and scalable algorithms for segmenting very large 3D images of brain tissue. Currently, light and electron microscopy can now produce terascale 3D images within hours. Extracting the information ...
Small-molecule inhibition of general transcriptional regulators in cancer
(Massachusetts Institute of Technology, 2016)
Transcription is frequently deregulated in cancer, but targeting of transcriptional processes for cancer therapy has thus far been limited to nuclear receptors. Recent studies, however, have suggested that inhibitors of ...
Studies of amino acid sensing by the mTORC 1 pathway
(Massachusetts Institute of Technology, 2016)
The mTOR complex 1 (mTORC 1) protein kinase is a master growth regulator that responds to multiple cues from the local and systemic environment surrounding the cell. Nutrients and growth factors are both required to activate ...
Interfacial engineering to control phase transitions : applications in icing and mineral scale fouling
(Massachusetts Institute of Technology, 2016)
Icing and scale fouling affect the functioning of a number of industries. The problems due to ice accretion have been prevalent for decades in a number of systems including aircrafts, wind turbines and power lines. Similarly, ...
Expansion microscopy : improving imaging through uniform tissue expansion
(Massachusetts Institute of Technology, 2016)
Until the past decade, optical microscopy of biological specimens was strongly limited by diffraction and scattering, affecting imaging resolution and depth, respectively. Now, numerous methods are available to overcome ...
Three essays on econometrics
(Massachusetts Institute of Technology, 2014)
This thesis consists of three chapters that cover separate topics in econometrics. The first chapter demonstrate a negative result on the asymptotic sizes of subset Anderson- Rubin tests with weakly identified nuisance ...
Impact of morphology and confinement effects on the properties of aligned nanofiber architectures
(Massachusetts Institute of Technology, 2016)
The intrinsic and scale-dependent properties of nanofibers (NFs), nanowires, and nanotubes have made them the focus of many application-specific nanostructured materials studies. However, various NF morphology and proximity ...
Optimal standoff imaging using structured laser illumination and graphical models
(Massachusetts Institute of Technology, 2014)
Structured illumination can be used to form images without using a lens or a detector array. A series of spatially-structured laser pulses is cast on the scene of interest, and a single-detector power measurement is made ...