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Now showing items 11-20 of 20
Quality improvement strategy in a dynamic aerospace manufacturing environment
(Massachusetts Institute of Technology, 2014)
In the manufacturing of any complex product it is a generally accepted phenomenon that defects will occur at various stages in the process. In aircraft modification and repair facilities, the low levels of automation and ...
Improving the inbound supply chain through dynamic pickup windows
(Massachusetts Institute of Technology, 2014)
Amazon is one of the world's largest retailers with revenues of $74.5 billion in 2013 and 22% growth over 2012. As Amazon continues to grow and offer greater selection, more products are flowing through an expanding inbound ...
Analysis of randomly occurring high injection forces in an insulin delivery device
(Massachusetts Institute of Technology, 2014)
During manufacturing scale-up of a new product, new failure modes often surface which require corrective action. However, as production numbers of an insulin injection device pass 200 million per year, testing continues ...
External operations portfolio analysis and segmentation
(Massachusetts Institute of Technology, 2014)
This thesis focuses on a medical device manufacturer, Company X, using a razor-and-blades business strategy, in which surgical instruments are offered to customers at little or no cost in order to facilitate the sale of ...
Streamlining data management in drug product commercialization and manufacturing
(Massachusetts Institute of Technology, 2014)
Effective execution and alignment of data management across development and manufacturing teams is essential for Amgen's Drug Product Technology group to realize its main goals of shortening the development timeline and ...
Creating a corporate strategy for utilizing supply chain simulation, optimization and visualization
(Massachusetts Institute of Technology, 2014)
Computer based supply chain simulation, optimization, and visualization capability have changed significantly in the past 45 years, expanding capability in lockstep with increases in computational power. The increase in ...
Inventory management for perishable goods using simulation methods
(Massachusetts Institute of Technology, 2014)
Amazon.com is the world's largest online retailer, and continues to grow its business by expanding into new markets and new product lines that have not traditionally been sold online. These product categories create new ...
Tactical planning optimization for campaign scheduling of active pharmaceutical ingredient production based on monoclonal antibodies
(Massachusetts Institute of Technology, 2014)
Monoclonal Antibodies (mAb's) are the fastest growing segment in the biopharmaceutical industry. They are used today as therapeutics and diagnostics for several medical applications, including various types of cancer, ...
Optimizing procurement and handling costs in a utility
(Massachusetts Institute of Technology, 2014)
We propose a novel method to quantify the cost of activities involved in the picking portion of order fulfillment. We adapt the general method of picking cost quantification to the specific situation of TP&G, a publicly ...
Technology maturity analysis for assessing capacity and schedule risk of future automation projects
(Massachusetts Institute of Technology, 2014)
The need to improve risk assessment methods for automation projects within United States manufacturers exists due to a shift toward increased in factory automation stemming from industry pressure to reduce manufacturing ...