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Now showing items 21-29 of 29
Improving operational effectiveness in the job-shop environment through discrete event simulation and innovative process design
(Massachusetts Institute of Technology, 2018)
A key value stream for Company X is a manufacturing area dedicated to production of precision electro-mechanical systems, of which they are contracted to service during the complete lifecycle. Currently, the production ...
Congestion reduction in the Emergency Department of Massachusetts General Hospital
(Massachusetts Institute of Technology, 2018)
The MGH Emergency Department (ED) and General Medicine Floor currently experience heavy patient volume and rising patient wait times, despite recent capacity expansions. While several projects have been piloted to divert ...
Lean principles in an aircraft assembly process
(Massachusetts Institute of Technology, 2018)
A universal imperative of most manufacturing firms is to lower cost, increase production rate, and deliver exceptional quality for every product. The manufacturing firm that springs to mind as the standard bearer for all ...
Simulation and optimization of outbound operations in an e-grocer's warehouse
(Massachusetts Institute of Technology, 2018)
A second wave of online grocery retailers ("e-grocers") emerged in late 2000's after dot.com companies, such as Webvan, Streamline and Homegrocer, failed to break into the grocery market despite investing heavily on automated ...
Enhancing the design and procurement of single-use assemblies in biomanufacturing by implementing modular specifications
(Massachusetts Institute of Technology, 2018)
Usage of single-use systems (SUS) in biomanufacturing has expanded rapidly in recent years. Amgen uses SUS at several commercial manufacturing sites, in addition to pilot plants and clinical production. Each single-use ...
Deep learning for automated visual inspection of uncured rubber
(Massachusetts Institute of Technology, 2018)
This thesis proposes a data-driven approach to automate the visual inspection of uncured rubber tire assemblies. Images collected from a machine vision system are used to develop proof of concept predictive models to ...
Predictive earthquake damage modeling for natural gas distribution infrastructure
(Massachusetts Institute of Technology, 2018)
The Pacific Gas and Electric Company (PG&E) operates and maintains 48,000 miles of natural gas pipeline, serving over 4.3 million customer accounts. Along with water, electric power, and transportation services, these ...
Oral drug delivery as an alternative to needle-based injection for large molecules : an assessment of the field & evaluation of high-priority technologies
(Massachusetts Institute of Technology, 2018)
Oral delivery of large molecules is widely considered the "holy grail" of drug delivery, but attempts to achieve this within the past century have been met with a lack of success, confounded by low bioavailability. Novel ...
Virtual pooling approximation using longest path network optimization
(Massachusetts Institute of Technology, 2018)
Abstract This thesis proposes a network swapping mechanism to approximate a virtual finished goods inventory pool under the constraint of fragmented commercial channel ownership. Globally, Caterpillar sells its product ...