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Characterization of the cost of forecast error in a complex supply chain
(Massachusetts Institute of Technology, 1998)
The importance of forecast accuracy is increasing in the semiconductor industry due to two compounding factors. The complexity of the manufacturing process is increasing which causes manufacturing cycle times to increase ...
Strategic capacity planning using data science, optimization, and machine learning
(Massachusetts Institute of Technology, 2020)
Raytheon's Circuit Card Assembly (CCA) factory in Andover, MA is Raytheon's largest factory and the largest Department of Defense (DOD) CCA manufacturer in the world. With over 500 operations, it manufactures over 7000 ...
Leveraging flexible manufacturing to streamline new product launch processes
(Massachusetts Institute of Technology, 2020)
Johnson & Johnson Vision (JJV), manufacturer of the ACUVUE® Brand Contact Lenses, is committed to launching new contact lens products every year to maintain competitive edge and long-term relevancy. However, manufacturing ...
Integrating agile within complex hardware development via additive manufacturing
(Massachusetts Institute of Technology, 2020)
A major benefit of Additive Manufacturing (AM) is a faster timeline from design to fabrication. As AM has matured to be able to create functional prototypes and end-use products, the ability to quickly fabricate physical ...
Additive manufacturing applications and implementation in aerospace
(Massachusetts Institute of Technology, 2020)
Many aerospace companies are turning to additive manufacturing solutions to stream-line current production processes and open opportunities for on-demand producibility. While many OEMs are drawn to the appeal of the benefits ...
Using discrete-event simulation to increase system capacity : a case study of an assembly plant
(Massachusetts Institute of Technology, 2020)
As part of its effort to introduce new technology and to improve the manufacturing system for the 777X production line, Boeing has made a significant capital investment in the Composite Wing Center (CWC). The new facility ...
Measuring machine interference to evaluate an operator cross-training program
(Massachusetts Institute of Technology, 2000)
Antibody drug discovery: From Idea to Biotherapeutic Molecule
(Massachusetts Institute of Technology, 2016)
Graybel (a fictitious name used for privacy reasons) is a large developer of pharmaceuticals. Graybel's Antibody Protein Engineering Group (APEG) is responsible for early stage drug development of biotherapeutic molecules. ...
Implementation of automated visual inspection machines in biopharmaceutical industry
(Massachusetts Institute of Technology, 2019)
Currently, manual visual inspection is the gold standard for the required visual inspection of particulate matter in parenteral medicines. Automated visual inspection machines offer an opportunity for Amgen to improve ...
Investigating the feasibility and impact of integrating wire-arc additive manufacturing in aerospace tooling applications
(Massachusetts Institute of Technology, 2020)
The use of wire-arc additive manufacturing (WAAM) as fabrication method for Iron-Nickel 36 (Invar36) alloy aerospace tooling is a growing area of interest for many tooling companies and composite aircraft manufacturers. ...