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C. Forbes Dewey, Jr.
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Recent Submissions
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(Biophysical Society, 2004-05)We have derived a broad, deterministic model of the steady-state actin cycle that includes its major regulatory mechanisms. Ours is the first model to solve the complete nucleotide profile within filaments, a feature that ...
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(Biophysical Society, 1998-09)The analogous techniques of photoactivation of fluorescence (PAF) and fluorescence recovery after photobleaching (FRAP) have been applied previously to the study of actin dynamics in living cells. Traditionally, ...
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(Biophysical Society, 1996)Current modeling of endothelial cell mechanics does not account for the network of F-actin that permeates the cytoplasm. This network, the distributed cytoplasmic structural actin (DCSA), extends from apical to basal ...
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(Biophysical Society, 1995)A continuum model describing the steady-state actin dynamics of the cytoskeleton of living cells Has been developed to aid in the interpretation of photoactivated fluorescence experiments. In a simplified cell geometry, ...
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Regulation of Adenine Nucleotide Concentration at Endothelium-Fluid Interface by Viscous Shear Flow (Biophysical Society, 1993)The action of adenine nucleotides on vascular endothelial cells is apparently mediated by the local flow conditions. Because nucleotides are sequentially degraded from ATP - ADP - AMP -- adenosine by ecto-enzymes at the ...
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