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Browsing Communications by Title

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  • Knight, Thomas (MIT Artificial Intelligence Laboratory; MIT Synthetic Biology Working Group, 2003)
    The lack of standardization in assembly techniques for DNA sequences forces each DNA assembly reaction to be both an experimental tool for addressing the current research topic, and an experiment in and of itself. One ...
  • Endy, Drew (2005-09-29)
    This document provides background material in support of the 2005 intercollegiate Genetically Engineered Machine Competition (aka iGEM). Herein, you can read quick summaries of earlier competitions and courses, obtain a ...
  • Collett, Marc (2007-12-04)
    In 2002, a team of researchers at the State University of New York led by Eckard Wimmer assembled a DNA template for the RNA poliovirus using an internet-available nucleotide sequence and mail order synthetic ...
  • Endy, Drew (2013-03-27)
    Research presentation on recent and unpublished work before the MIT Synthetic Biology Working Group on 24 September 2012 in MIT Building 56.
  • Brent, Roger (2006-11-22)
    During the 20th century, advances in biological understanding sparked a global revolution in biological capability, or RBC. Since that time, the revolution has proceeded in a Moore's-law-like fashion for many decades. ...
  • Endy, Drew (2006-06-15)
    I am a science journalist with the Guardian newspaper in London. We are a national daily paper. I am hoping to put together an investigative piece on how easy (or not) it would be for a would-be terrorist to put together ...
  • Soergel, David; Choi, Kirindi; Thomson, Ty; Doane, Jay; George, Brian; Morgan-Linial, Ross; Brent, Roger; Endy, Drew (2008-06-19)
    We describe an open source software tool called MONOD, for Modeler’s Notebook and Datastore, designed to capture and communicate knowledge generated during the process of building models of many-component biological ...
  • Phillips, Ira; Silver, Pamela (2006-04-20)
    The existing biobrick assembly technique[1] provides a straightforward way to combine standardized biological components, termed biobricks. This system, however, is limited in that each protein-encoding biobrick must ...
  • Brent, Roger (2006-11-21)
    Peter Parker and Uncle Ben are on my mind. The reason is that is that a month ago I was jumped by Craig Venter. There were TV cameras around. The live audience was an interesting, edgy mix, on the interface between ...
  • Bügl, Hans; Danner, John; Molinari, Robert; Mulligan, John; Roth, David; Wagner, Ralf; Budowle, Bruce; Scripp, Robert; Smith, Jenifer; Steele, Scott; Church, George; Endy, Drew (2006-12-12)
    Few developments have leapfrogged over predecessor technology as quickly and extensively as synthetic biology. Based on cutting-edge DNA synthesis technology, synthetic biology has already fueled an expansion of ...
  • Thomson, Ty M; Endy, Drew (International Conference on Systems Biology, 2005-10-21)
    The use of traditional tools for the discovery and characterization of biological systems has resulted in a wealth of biological knowledge. Unfortunately, only a small portion of the biological world is well-understood ...
  • Win, Maung Nyan; Smolke, Christina (2009-07-29)
    This supplement provides additional detail on the data analysis methods and the raw data for the RNA devices presented in the published manuscript and supporting online material. The information provided in the current ...
  • Chan, Leon; Kosuri, Sriram; Endy, Drew (2004-10)
    Natural biological systems are selected by evolution to continue to exist. Evolution might give rise to complicated systems that are difficult to discover, measure, model, and direct. Here, we redesign the genome of a ...
  • Vincent Rouilly, Barry Canton; Poul Nielsen, Richard Kitney (2007-10-04)
    One of the main goals in Synthetic Biology is to assess the feasibility of building novel biological systems from interchangeable and standardized parts. In order to collect and share parts, a Registry of standardized DNA ...
  • Fleming, Diane (2007-12-04)
    The ability to synthesize molecules found in living organisms is not new for scientists in the fields of biochemistry and molecular biology. However, the “synthetic biology” made possible by the genetic mapping of ...
  • Sanghvi, Yogesh (2007-12-04)
    Until recently, the synthesis of DNA has been a tedious, time consuming, expensive and experimentally challenging task. But advances in automated instrumentation and improved chemistry have now made it possible to make ...
  • Jones, Robert (2007-12-04)
    Currently the vast majority of DNA synthesis is performed by service companies or by in-house central facilities in universities and large companies. The DNA synthesis industry provides researchers with custom DNA at ...
  • Kosuri, Sriram (2007-02-02)
    Our understanding of why biological systems are designed in a particular way would benefit from biophysically-realistic models that can make accurate predictions on the time-evolution of molecular events given arbitrary ...
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