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Engineering transcription-based digital logic devices

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Show simple item record Shetty, Reshma P. Knight, Thomas F. Jr 2005-12-01T20:13:19Z 2005-12-01T20:13:19Z 2005-10-20
dc.description Poster presented at the 2005 ICSB meeting, held at Harvard Medical School in Boston, MA. en
dc.description.abstract The goal of Synthetic Biology is to engineer systems from biological parts. One class of systems are those whose purpose is to process information. My work seeks to build transcription-based devices for use in combinational digital logic. Preliminary characterization experiments show that existing devices fall short of desired device behavior. I propose to develop a novel implementation of transcription-based logic by designing synthetic transcription factors from well-characterized DNA binding and dimerization domains. Initial modeling work serves to inform design of these devices. en
dc.format.extent 186621 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US en
dc.publisher Sixth International Conference on Systems Biology en
dc.subject Synthetic Biology en
dc.subject Engineered Biological Systems en
dc.subject Transcription-based logic en
dc.title Engineering transcription-based digital logic devices en
dc.type Other en
dc.identifier.citation R.P. Shetty and T.F. Knight Jr. Engineering transcription-based digital logic. Sixth International Conference on Systems Biology, 2005. en

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