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Browsing School of Engineering by Title

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  • Li, Meng, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2010)
    Many therapeutically useful and critically important drugs are inhibitors of particular enzymes in a signaling pathway. The efficiency with which an inhibitor inactivates its target can be characterized by the binding ...
  • Su, Hua, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2006)
    This thesis applies recent advances in the field of robust optimization to the optimal control of multiclass queueing networks. We develop models that take into account the uncertainty of interarrival and service time in ...
  • Chen, Si, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2009)
    This research aims to provide tractable approaches to price options using robust optimization. The pricing problem is reduced to a problem of identifying the replicating portfolio which minimizes the worst case arbitrage ...
  • Lim, Lui Cheng (Massachusetts Institute of Technology, 2008)
    Forest operations planning is a complex decision process which considers multiple objectives on the strategic, tactical and operational horizons. Decisions such as where to harvest and in what order over different time ...
  • Lu, Yun (Massachusetts Institute of Technology, 2007)
    We address the problem of designing a transportation network in the presence of demand uncertainty, multiple origin-destination pairs and a budget constraint for the overall construction cost, under the behavioral assumption ...
  • Lui, Ho Man (Massachusetts Institute of Technology, 2006)
    In this thesis we investigate the ability of the Runge-Kutta Discontinuous Galerkin (RKDG) method to provide accurate and efficient solutions of the Boltzmann equation. Solutions of the Boltzmann equation are desirable in ...
  • Wachtel, Amanda M. (Amanda Marie) (Massachusetts Institute of Technology, 2013)
    As cities evolve in size and complexity, their component systems become more interconnected. Comprehensive modeling and simulation is needed to capture interactions and correctly assess the impact of changes. This thesis ...
  • Hu, Yuwei, S.M. Massachusetts Institute of Technology; Lim, Chin Soon (Massachusetts Institute of Technology, 2009)
    In a DNA sequencing workflow, a biological sample has to pass through multiple process steps. Two consecutive steps are hydroshearing and library construction. Samples arrive randomly into the inventory and are to complete ...
  • Hu, Sha, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2006)
    In this thesis, we use a semidefinite relaxation based branch-and-bound method to solve nonconvex quadratic programming problems. Firstly, we show an interval branch-and-bound method to calculate the bounds for the minimum ...
  • Saxena, Vibhu Prakash (Massachusetts Institute of Technology, 2010)
    Many models of physical systems oscillate periodically and exhibit both discrete-state and continuous-state dynamics. These systems are called oscillating hybrid systems and find applications in diverse areas of science ...
  • Yuan, Rong, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2013)
    In this research we model a job shop that produces a set of discrete parts in a make-to-stock setting. The intent of the research is to develop a planning model to determine the optimal operating tactics that minimize the ...
  • Xu, Song, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2007)
    Model Order Reduction (MOR) is becoming increasingly important in computational applications. At the same time, the need for more comprehensive models of systems is generating problems with increasing numbers of outputs ...
  • Saà-Seoane, Joel (Massachusetts Institute of Technology, 2011)
    Periodicity can change materials properties in a very unintuitive way. Many wave propagation phenomena, such as waveguides, light bending structures or frequency filters can be modeled through finite periodic structures ...
  • Prakash, Kshitij (Massachusetts Institute of Technology, 2009)
    IGCC with CO2 capture offers an exciting approach for cleanly using abundant coal reserves of the world to generate electricity. The present state-of-the-art synthesis gas (syngas) cleanup technologies in IGCC involve ...
  • Zhang, Yifeng, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2008)
    Project scheduling is an important research and application area in engineering management. Recent research in this area addresses resource constraints as well as stochastic durations. This thesis presents a simulation-based ...
  • Mohnot, Anshul (Massachusetts Institute of Technology, 2008)
    The present work aims to address the problem of fluid-structure interaction using a discontinuous Galerkin approach. Starting from the Navier-Stokes equations on a fixed domain, an arbitrary Lagrangian Eulerian (ALE) ...
  • Gaustad, Gabrielle G (Massachusetts Institute of Technology, 2009)
    A key element for realizing long term sustainable use of any metal will be a robust secondary recovery industry. Secondary recovery forestalls depletion of non-renewable resources and avoids the deleterious effects of ...
  • Liang, Li (Massachusetts Institute of Technology, 2010)
    Hydrogen fuel is considered one of the major emerging renewable substitutes for fossil fuel. A crucial factor as to whether hydrogen will be successful depends on its cost as a substitute. Recently, there has been a growing ...
  • Ooi, Boon Hooi (Massachusetts Institute of Technology, 2008)
    BioMEM microfluidic weirs enable biologists to study biological processes at the cell level. A novel substrate-affixed microfluidic array of weirs allows active sorting of cells via control electrodes. The ability of the ...
  • Liem, Rhea Patricia (Massachusetts Institute of Technology, 2007)
    This research introduces a systematic method to reduce the complexity of large-scale blackbox systems for which the governing equations are unavailable. For such systems, surrogate models are critical for many applications, ...
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