Browsing Molecular Engineering of Biological and Chemical Systems (MEBCS) by Title
Now showing items 54-73 of 106
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A New Class of Nonionic Photosensitive Surfactants: Some Insights Concerning Conformations
(2005-01)We report on a new class of nonionic, photosensitive surfactants consisting of a polar di(ethylene oxide) head group attached to an alkyl spacer of between two and eight methylene groups, coupled through an ether linkage ... -
A New Class of Photoresponsive Surfactants
(2003-01)Recently, surface tension has been shown to be important in emerging high technologies, such as in pumping and control of flow in microfluidic devices, in microchemical analysis of complex fluids, and in rapid DNA screening, ... -
NIR-Sensitive Au-Au₂S Nanoparticles for Drug Delivery
(2003-01)Near IR (NIR) sensitive Au-Au₂S nanoparticles were prepared by mixing HAuCl₄ and Na₂S in aqueous solutions. An anti-tumor drug, cis-platin, was adsorbed onto Au-Au₂S nanoparticle surface via the 11-mercaptoundecanoic acid ... -
Novel pH Responsive Amphiphilic Diblock Copolymers with Reversible Micellization Properties
(2004-01)Di-block copolymer of poly[methacrylic acid-block-2-(diethylamino)ethyl methacrylate] [P(MAA-b-DEA)] with narrow molecular weight distribution was synthesized using the atom transfer radical polymerization (ATRP) technique. ... -
On the Electrostatics of Pneumatic Conveying of Granular Materials
(2004-01)In this work the electrostatics of the pneumatic conveying of granular materials in a non-conducting (PVC) vertical pipe is studied using Electrical Capacitance Tomography (ECT) system. The non-conducting wall in general ... -
On the Fabrication of Microparticles Using Electrohydrodynamic Atomization Method
(2005-01)A new approach for the control of the size of particles fabricated using the Electrohydrodynamic Atomization (EHDA) method is being developed. In short, the EHDA process produces solution droplets in a controlled manner, ... -
On the Oxidation of Methionine Residues during the Storage of Protein Pharmaceuticals in an Aqueous Formulation
(2004-01)This study addresses the fundamentals of an important degradation pathway of storing protein pharmaceuticals in an aqueous formulation, oxidation of methionine residues by peroxides. First, a mechanism by which methionine ... -
Over Expression of the CMP-sialic Acid Transporter in Chinese Hamster Ovary Cells Leads to Increased Sialylation
(2005-01)Most glyco-engineering approaches used to improve quality of recombinant glycoproteins involve the manipulation of glycosyltransferase and/or glycosidase expression. We investigated whether the over expression of nucleotide ... -
Particle Image Velocimetry Study on the Stripe Formation in Vertically Vibrated Granules
(2004-01)Recently, granules under vertical vibrations receive many attentions due to their importance in theoretical research and engineering application. In this paper, a two-dimensional Particle Image Velocimetry (PIV) system was ... -
Photo- and Thermoinduced Sol-Gel Transitions in Blends of Azobenzene Copolymers and Pluronic Surfactants
(2006-01)Novel self-assembling copolymers of 4-Methacryloyloxyazobenzene and NN-dimethylacrylamide (MOAB-DMA) exhibiting a pronounced photoviscosity effects in water are described. An optimum polymer architecture corresponding to ... -
Preparation of Polymer-Coated Functionalized Ferrimagnetic Iron Oxide Nanoparticles*
(2004-01)A simple chemical method to synthesize PMAA coated maghemite nanoparticles is described. Monomer methacrylic acid molecules were absorbed onto the synthesized ferrimagnetic nanoparticles followed by polymerization. The ... -
Preparation of PtNi Nanoparticles for the Electrocatalytic Oxidation of Methanol
(2004-01)Carbon supported PtNi nanoparticles were prepared by hydrazine reduction of Pt and Ni precursor salts under different conditions, namely by conventional heating (PtNi-1), by prolonged reaction at room temperature (PtNi-2) ... -
Prion Protein is Expressed on Long-term Repopulating Hematopoietic Stem Cells and is Necessary for their Self-renewal
(2005-01)We show that the prion protein (PrP) is expressed on the surface of bone marrow cell populations enriched in long-term repopulating hematopoietic stem cells. Affinity purification of the PrP-positive and PrP-negative ... -
Profiling of ligand-receptor induced signalling- a novel protein chip technique
(2004-01)Cellular signalling pathways are the master controls of the biology of the cell, which includes cell communication, growth, death, and differentiation. The activities of these signalling proteins directly influence gene ... -
Protein Microarray: "Theory" to "Real Practice"
(2005-01)Fueled by ever-growing genomic information and rapid developments of proteomics–the large scale analysis of proteins and mapping its functional role has become one of the most important disciplines for characterizing complex ... -
Proteins in Mixed Solvents: A Molecular-level Perspective
(2004-01)We present a statistical mechanical approach for quantifying thermodynamic properties of proteins in mixed solvents. This approach, based on molecular dynamics simulations which incorporate all atom models and the theory ... -
Quantification and signaling of alternatively spliced GFRα2 isoforms
(2003-01)Neurturin (NTN) belongs to the glial cell-line derived neurotrophic factor (GDNF) family of growth factors. Both NTN and GDNF have been shown to potently prevent the degeneration of dopaminergic neuron in vitro and in vivo. ... -
Quantitative linkage of physiology and gene expression through empirical model construction: an investigation of diabetes
(2003-01)A methodology for the construction of predictive empirical models of physiological characteristics from microarray data is presented. The method, applied here to the study of the development of diabetes and insulin resistance, ... -
Rare-Earth Doped LaF₃ Nanocrystals for Upconversion Fluorescence
(2006-01)Upconversion fluorescent nanocrystals, Yb-Er, Yb-Ho and Yb-Tm co-doped LaF₃ were chemically synthesized. The average particle size was 4.4 nm with a narrow size distribution of ± 0.3 nm. Under the 980 nm NIR excitation, ... -
Reduced Temperature Production of Recombinant Proteins to Increase Productivity in Mammalian Cell Culture
(2004-01)The production of recombinant proteins from an industrial perspective has one of its main goals is to increase the product concentration whether in batch, fed-batch or continuous perfusion bioreactor systems. However, a ...