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Browsing Computation for Design and Optimization - Master's degree by Title

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Browsing Computation for Design and Optimization - Master's degree by Title

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  • Relative effectiveness of inhibition strategies for control of biological signaling pathways 
    Li, Meng, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2010)
    Many therapeutically useful and critically important drugs are inhibitors of particular enzymes in a signaling pathway. The efficiency with which an inhibitor inactivates its target can be characterized by the binding ...
  • Robust fluid control of multiclass queueing networks 
    Su, Hua, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2006)
    This thesis applies recent advances in the field of robust optimization to the optimal control of multiclass queueing networks. We develop models that take into account the uncertainty of interarrival and service time in ...
  • Robust option pricing : An [epsilon]-arbitrage approach 
    Chen, Si, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2009)
    This research aims to provide tractable approaches to price options using robust optimization. The pricing problem is reduced to a problem of identifying the replicating portfolio which minimizes the worst case arbitrage ...
  • Robust scheduling in forest operations planning 
    Lim, Lui Cheng (Massachusetts Institute of Technology, 2008)
    Forest operations planning is a complex decision process which considers multiple objectives on the strategic, tactical and operational horizons. Decisions such as where to harvest and in what order over different time ...
  • Robust transportation network design under user equilibrium 
    Lu, Yun (Massachusetts Institute of Technology, 2007)
    We address the problem of designing a transportation network in the presence of demand uncertainty, multiple origin-destination pairs and a budget constraint for the overall construction cost, under the behavioral assumption ...
  • Runge-Kutta Discontinuous Galerkin method for the Boltzmann equation 
    Lui, Ho Man (Massachusetts Institute of Technology, 2006)
    In this thesis we investigate the ability of the Runge-Kutta Discontinuous Galerkin (RKDG) method to provide accurate and efficient solutions of the Boltzmann equation. Solutions of the Boltzmann equation are desirable in ...
  • Scheduling of biological samples for DNA sequencing 
    Hu, Yuwei, S.M. Massachusetts Institute of Technology; Lim, Chin Soon (Massachusetts Institute of Technology, 2009)
    In a DNA sequencing workflow, a biological sample has to pass through multiple process steps. Two consecutive steps are hydroshearing and library construction. Samples arrive randomly into the inventory and are to complete ...
  • Semidefinite relaxation based branch-and-bound method for nonconvex quadratic programming 
    Hu, Sha, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2006)
    In this thesis, we use a semidefinite relaxation based branch-and-bound method to solve nonconvex quadratic programming problems. Firstly, we show an interval branch-and-bound method to calculate the bounds for the minimum ...
  • Sensitivity analysis of oscillating hybrid systems 
    Saxena, Vibhu Prakash (Massachusetts Institute of Technology, 2010)
    Many models of physical systems oscillate periodically and exhibit both discrete-state and continuous-state dynamics. These systems are called oscillating hybrid systems and find applications in diverse areas of science ...
  • A shifting method for dynamic system Model Order Reduction 
    Xu, Song, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2007)
    Model Order Reduction (MOR) is becoming increasingly important in computational applications. At the same time, the need for more comprehensive models of systems is generating problems with increasing numbers of outputs ...
  • Simulation and design optimization for linear wave phenomena on metamaterials 
    Saà-Seoane, Joel (Massachusetts Institute of Technology, 2011)
    Periodicity can change materials properties in a very unintuitive way. Many wave propagation phenomena, such as waveguides, light bending structures or frequency filters can be modeled through finite periodic structures ...
  • Simulation and optimization of hot syngas separation processes in integrated gasification combined cycle 
    Prakash, Kshitij (Massachusetts Institute of Technology, 2009)
    IGCC with CO2 capture offers an exciting approach for cleanly using abundant coal reserves of the world to generate electricity. The present state-of-the-art synthesis gas (syngas) cleanup technologies in IGCC involve ...
  • A simulation-based resource optimization and time reduction model using design structure matrix 
    Zhang, Yifeng, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2008)
    Project scheduling is an important research and application area in engineering management. Recent research in this area addresses resource constraints as well as stochastic durations. This thesis presents a simulation-based ...
  • Solution of fluid-structure interaction problems using a discontinuous Galerkin technique 
    Mohnot, Anshul (Massachusetts Institute of Technology, 2008)
    The present work aims to address the problem of fluid-structure interaction using a discontinuous Galerkin approach. Starting from the Navier-Stokes equations on a fixed domain, an arbitrary Lagrangian Eulerian (ALE) ...
  • Stochastic methods for improving secondary production decisions under compositional uncertainty 
    Gaustad, Gabrielle G (Massachusetts Institute of Technology, 2009)
    A key element for realizing long term sustainable use of any metal will be a robust secondary recovery industry. Secondary recovery forestalls depletion of non-renewable resources and avoids the deleterious effects of ...
  • Supply chain network for hydrogen transportation in Spain 
    Liang, Li (Massachusetts Institute of Technology, 2010)
    Hydrogen fuel is considered one of the major emerging renewable substitutes for fossil fuel. A crucial factor as to whether hydrogen will be successful depends on its cost as a substitute. Recently, there has been a growing ...
  • Surrogate-based optimization of a BioMEMs microfluidic weir 
    Ooi, Boon Hooi (Massachusetts Institute of Technology, 2008)
    BioMEM microfluidic weirs enable biologists to study biological processes at the cell level. A novel substrate-affixed microfluidic array of weirs allows active sorting of cells via control electrodes. The ability of the ...
  • Surrogate modeling for large-scale black-box systems 
    Liem, Rhea Patricia (Massachusetts Institute of Technology, 2007)
    This research introduces a systematic method to reduce the complexity of large-scale blackbox systems for which the governing equations are unavailable. For such systems, surrogate models are critical for many applications, ...
  • A tactical planning model for a serial flow manufacturing system 
    Huang, Bin, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2010)
    This project aims to improve the operation and planning of a specific type of manufacturing system, a serial flow line that entails a sequence of process stages. The objective is to investigate inventory policy, raw material ...
  • Testing for jumps and cojumps in financial markets 
    Ju, Cheng, S.M. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2010)
    In this thesis, we introduce a new testing methodology to detect cojumps in multi-asset returns. We define a cojump as a jump in at least one dimension of the return processes. For a multivariate process that follows a ...
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