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Novel pH Responsive Amphiphilic Diblock Copolymers with Reversible Micellization Properties

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dc.contributor.author Palaniswamy, R.
dc.contributor.author Dai, S.
dc.contributor.author Tam, Michael K. C.
dc.contributor.author Gan, L.H.
dc.date.accessioned 2003-12-16T14:05:05Z
dc.date.available 2003-12-16T14:05:05Z
dc.date.issued 2004-01
dc.identifier.uri http://hdl.handle.net/1721.1/3938
dc.description.abstract Di-block copolymer of poly[methacrylic acid-block-2-(diethylamino)ethyl methacrylate] [P(MAA-b-DEA)] with narrow molecular weight distribution was synthesized using the atom transfer radical polymerization (ATRP) technique. The micellization behavior of the P(MAA-b-DEA) copolymer in aqueous solution at room temperature and different pH values were examined by potentiometric and conductivity titration, UV-Visible spectrophotometry, ¹H-NMR, static and dynamic laser light scattering. At low pH (< 4.2), core-shell micelles were formed with MAA core and protonated DEA shell. At moderate pH values, the polymer precipitated from water and formed a cloudy solution, where the polymer chains aggregated into larger particles resembling that of a hard sphere induced by electrostatic interactions. At high pH (> 9.5), core-shell like micelles consisting of hydrophobic DEA core and ionized MAA shell were re-established. en
dc.description.sponsorship Singapore-MIT Alliance (SMA) en
dc.format.extent 284986 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.relation.ispartofseries Molecular Engineering of Biological and Chemical Systems (MEBCS);
dc.subject ATRP en
dc.subject laser light scattering en
dc.subject P(MAA-b-DEA) en
dc.subject stimuli-responsive en
dc.title Novel pH Responsive Amphiphilic Diblock Copolymers with Reversible Micellization Properties en
dc.type Article en


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