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Cancer and the clock : chronotherapy's struggle for legitimacy

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dc.contributor.advisor Thomas Levenson. en_US Kagan, Emily M en_US
dc.contributor.other MIT Program in Writing & Humanistic Studies. en_US 2007-11-15T18:08:07Z 2007-11-15T18:08:07Z 2005 en_US 2005 en_US
dc.description Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Humanities, Program in Writing and Humanistic Studies, 2005. en_US
dc.description Includes bibliographical references (leaves 41-44). en_US
dc.description.abstract Circadian rhythms govern almost every process in our bodies. Chronotherapy is the practice of giving medications in synchrony with these rhythms. For cancer chemotherapy, study after study has shown that paying attention timing makes a big difference. Patients receiving chemotherapy at the specified times had their tumors shrink faster and suffered from fewer side effects. In a few studies, patients receiving chemotherapy linked to circadian rhythms survived longer than those who received their drugs at any random time of day. Yet some 25 years after the first human trials, most oncologists still have never heard of chronotherapy. This is the story of why. From money to attitude problems, logistics to dogma, the tale of chronotherapy's dance around the fringes of oncology has almost nothing to do with the science. Instead it is a story of a promising new therapeutic concept and how it must contend with the interests of drug companies, insurance providers and an overburdened medical system steeped in a culture famously resistant to change. en_US
dc.description.statementofresponsibility by Emily M. Kagan. en_US
dc.format.extent 44 leaves en_US
dc.language.iso eng en_US
dc.publisher Massachusetts Institute of Technology en_US
dc.rights M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. en_US
dc.subject Program in Writing and Humanistic Studies. en_US
dc.title Cancer and the clock : chronotherapy's struggle for legitimacy en_US
dc.type Thesis en_US S.M. en_US
dc.contributor.department MIT Program in Writing & Humanistic Studies. en_US
dc.identifier.oclc 64637483 en_US

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