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Vertical hydrodynamic focusing in an isotropically etched glass microfluidic device

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dc.contributor.advisor Daniel E. Ehrlich and Anette Hosoi. en_US
dc.contributor.author Lin, Tony An-tong en_US
dc.contributor.other Massachusetts Institute of Technology. Dept. of Mechanical Engineering. en_US
dc.date.accessioned 2008-01-10T15:51:42Z
dc.date.available 2008-01-10T15:51:42Z
dc.date.copyright 2007 en_US
dc.date.issued 2007 en_US
dc.identifier.uri http://hdl.handle.net/1721.1/39886
dc.description Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007. en_US
dc.description Includes bibliographical references (p. 107-109). en_US
dc.description.abstract The development of microfluidic devices has enabled precision control of nanoliter-scale environments and reactions. Vertical hydrodynamic focusing is one possible way to improve the optical performance of these devices while maintaining precision control. Vertical hydrodynamic focusing was studied through the use of computation fluid dynamics (ADINA) and experimental testing. It was found that the nonlinear effects of flow rate and geometry on the layering profile could be used to tune and correct the flow. A syringe pump-driven microfluidic device was fabricated out of isotropically etched and bonded glass plates and fluorescent confocal microscopy was used to verify computational models. en_US
dc.description.statementofresponsibility by Tony An-tong Lin. en_US
dc.format.extent 109 p. en_US
dc.language.iso eng en_US
dc.publisher Massachusetts Institute of Technology en_US
dc.rights M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. en_US
dc.rights.uri http://dspace.mit.edu/handle/1721.1/7582
dc.subject Mechanical Engineering. en_US
dc.title Vertical hydrodynamic focusing in an isotropically etched glass microfluidic device en_US
dc.type Thesis en_US
dc.description.degree S.M. en_US
dc.contributor.department Massachusetts Institute of Technology. Dept. of Mechanical Engineering. en_US
dc.identifier.oclc 182540246 en_US


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