7.88J / 5.48J / 7.24J / 10.543J Protein Folding Problem, Fall 2003
Alternative Title:
Protein Folding Problem
Author:
King, Jonathan, 1941-; Gossard, D.
Date Issued:
2003-12
Abstract:
Mechanisms by which the amino acid sequence of polypeptide chains determines their three-dimensional conformation. Topics include: sequence determinants of secondary structure; folding of newly synthesized polypeptide chains within cells; unfolding and refolding of proteins in vitro; folding intermediates aggregation and competing off-pathway reactions; role of chaperonins, isomerases, and other helper proteins; protein recovery problems in the biotechnology industry; diseases associated with protein folding defects.
Other Identifiers:
7.88J-Fall2003
Other Identifiers:
7.88J
5.48J
7.24J
10.543J
IMSCP-MD5-1bde92c2b081655dda551bd0934a7e5c
Keywords:
amino acid sequence, polypeptide chains, sequence determinants, synthesized polypeptide chains within cells, competing off-pathway reactions, chaperonins, isomerases, helper proteins, protein recovery problems, biotechnology industry, protein folding defects, 3-D conformation, globular proteins, fibrous proteins, kinetics, in vitro refolding, pathways, in vivo folding, synthesized proteins, aggregation, protein misfolding, human disease, protein folding, genome sequences, 7.88J, 5.48J, 7.24J, 10.543J, 7.88, 5.48, 7.24, 10.543, 260207, Structural Biology
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