| dc.contributor.author | King, Jonathan, 1941- | en_US |
| dc.contributor.author | Gossard, D. | en_US |
| dc.coverage.temporal | Fall 2003 | en_US |
| dc.date.issued | 2003-12 | |
| dc.identifier | 7.88J-Fall2003 | |
| dc.identifier | local: 7.88J | |
| dc.identifier | local: 5.48J | |
| dc.identifier | local: 7.24J | |
| dc.identifier | local: 10.543J | |
| dc.identifier | local: IMSCP-MD5-1bde92c2b081655dda551bd0934a7e5c | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/45544 | |
| dc.description.abstract | Mechanisms by which the amino acid sequence of polypeptide chains determines their three-dimensional conformation. Topics include: sequence determinants of secondary structure; folding of newly synthesized polypeptide chains within cells; unfolding and refolding of proteins in vitro; folding intermediates aggregation and competing off-pathway reactions; role of chaperonins, isomerases, and other helper proteins; protein recovery problems in the biotechnology industry; diseases associated with protein folding defects. | en_US |
| dc.language | en-US | en_US |
| dc.relation | | en_US |
| dc.rights.uri | Usage Restrictions: This site (c) Massachusetts Institute of Technology 2003. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license"). The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. | en_US |
| dc.subject | amino acid sequence | en_US |
| dc.subject | polypeptide chains | en_US |
| dc.subject | sequence determinants | en_US |
| dc.subject | synthesized polypeptide chains within cells | en_US |
| dc.subject | competing off-pathway reactions | en_US |
| dc.subject | chaperonins | en_US |
| dc.subject | isomerases | en_US |
| dc.subject | helper proteins | en_US |
| dc.subject | protein recovery problems | en_US |
| dc.subject | biotechnology industry | en_US |
| dc.subject | protein folding defects | en_US |
| dc.subject | 3-D conformation | en_US |
| dc.subject | globular proteins | en_US |
| dc.subject | fibrous proteins | en_US |
| dc.subject | kinetics | en_US |
| dc.subject | in vitro refolding | en_US |
| dc.subject | pathways | en_US |
| dc.subject | in vivo folding | en_US |
| dc.subject | synthesized proteins | en_US |
| dc.subject | aggregation | en_US |
| dc.subject | protein misfolding | en_US |
| dc.subject | human disease | en_US |
| dc.subject | protein folding | en_US |
| dc.subject | genome sequences | en_US |
| dc.subject | 7.88J | en_US |
| dc.subject | 5.48J | en_US |
| dc.subject | 7.24J | en_US |
| dc.subject | 10.543J | en_US |
| dc.subject | 7.88 | en_US |
| dc.subject | 5.48 | en_US |
| dc.subject | 7.24 | en_US |
| dc.subject | 10.543 | en_US |
| dc.title | 7.88J / 5.48J / 7.24J / 10.543J Protein Folding Problem, Fall 2003 | en_US |
| dc.title.alternative | Protein Folding Problem | en_US |
