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Fabrication process for openable microfluidic devices and externally actuated microfluidic switch

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dc.contributor.advisor Daniel J. Ehrlich and Todd Thorsen. en_US
dc.contributor.author Cartas Ayala, Marco Aurelio en_US
dc.contributor.other Massachusetts Institute of Technology. Dept. of Mechanical Engineering. en_US
dc.date.accessioned 2009-06-30T17:11:48Z
dc.date.available 2009-06-30T17:11:48Z
dc.date.copyright 2008 en_US
dc.date.issued 2008 en_US
dc.identifier.uri http://hdl.handle.net/1721.1/46057
dc.description Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2008. en_US
dc.description Includes bibliographical references (leaves 140-142). en_US
dc.description.abstract In this document I discuss the fabrication of metallic, aluminum and aluminum oxide, 3D micro channels, made with standard milling technology, along with two channel closing methods for openable devices: half cured-glued PDMS and Pressure Sensitive Adhesive (PSA) Film. Using the aluminum oxide coated micro channels, along with the half cured-glued PDMS process to close the channels and external fast speed valves for actuation, a microfluidic switch for cell sorting capable of operating at 48 Hz was designed, fabricated and tested. The use of aluminum as a channel substrate provides channel strength and short heat dissipation times, and the use of aluminum oxide enhances light energy absorption, which provides the possibility of further laser actuation. Also, the combination of micro fabrication process and actuation technique makes possible the further scaling and handling of large cells as cardiocytes. en_US
dc.description.statementofresponsibility by Marco Aurelio Cartas Ayala. en_US
dc.format.extent 142 leaves en_US
dc.language.iso eng en_US
dc.publisher Massachusetts Institute of Technology en_US
dc.rights M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. en_US
dc.rights.uri http://dspace.mit.edu/handle/1721.1/7582 en_US
dc.subject Mechanical Engineering. en_US
dc.title Fabrication process for openable microfluidic devices and externally actuated microfluidic switch en_US
dc.type Thesis en_US
dc.description.degree S.M. en_US
dc.contributor.department Massachusetts Institute of Technology. Dept. of Mechanical Engineering. en_US
dc.identifier.oclc 373873805 en_US


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