Now showing items 1-2 of 2

    • Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin 

      Ma, Sai; Zhang, Bing; LaFave, Lindsay M; Earl, Andrew S; Chiang, Zachary; e.a. (Elsevier BV, 2020)
      © 2020 Elsevier Inc. Cell differentiation and function are regulated across multiple layers of gene regulation, including modulation of gene expression by changes in chromatin accessibility. However, differentiation is an ...
    • In situ genome sequencing resolves DNA sequence and structure in intact biological samples 

      Payne, Andrew C; Chiang, Zachary D; Reginato, Paul L; Mangiameli, Sarah M; Murray, Evan M; e.a. (American Association for the Advancement of Science (AAAS), 2020-12)
      Understanding genome organization requires integration of DNA sequence and three-dimensional spatial context; however, existing genome-wide methods lack either base pair sequence resolution or direct spatial localization. ...