Browsing MIT Open Access Articles by Title
Now showing items 1649-1668 of 55746
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Amygdala Inputs to the Ventral Hippocampus Bidirectionally Modulate Social Behavior
(Society for Neuroscience, 2014-01)Impairments in social interaction represent a core symptom of a number of psychiatric disease states, including autism, schizophrenia, depression, and anxiety. Although the amygdala has long been linked to social interaction, ... -
Amygdala lesions do not compromise the cortical network for false-belief reasoning
(National Academy of Sciences (U.S.), 2015-04)The amygdala plays an integral role in human social cognition and behavior, with clear links to emotion recognition, trust judgments, anthropomorphization, and psychiatric disorders ranging from social phobia to autism. A ... -
Amygdala Reward Neurons Form and Store Fear Extinction Memory
(Elsevier BV, 2020-03)The ability to extinguish conditioned fear memory is critical for adaptive control of fear response, and its impairment is a hallmark of emotional disorders like post-traumatic stress disorder (PTSD). Fear extinction is ... -
Amygdala-ventral striatum circuit activation decreases long-term fear
(eLife Sciences Publications, Ltd., 2016-09)In humans, activation of the ventral striatum, a region associated with reward processing, is associated with the extinction of fear, a goal in the treatment of fear-related disorders. This evidence suggests that extinction ... -
Amygdala–medial prefrontal cortex connectivity relates to stress and mental health in early childhood
(Oxford University Press (OUP), 2018-03)Early life stress has been associated with disrupted functional connectivity between the amygdala and medial prefrontal cortex (mPFC), but it is unknown how early in development stress-related differences in amygdala-mPFC ... -
Amyloid Deposits: Protection Against Toxic Protein Species?
(Landes Bioscience, 2009-06)Neurodegenerative diseases ranging from Alzheimer’s disease and polyglutamine diseases to transmissible spongiform encephalopathies are associated with the aggregation and accumulation of misfolded proteins. In several ... -
An Amyloid Organelle: Solid State NMR Evidence for Cross-Beta Assembly of Gas Vesicles
(American Society for Biochemistry and Molecular Biology, 2012-01)Functional amyloids have been identified in a wide range of organisms, taking on a variety of biological roles and being controlled by remarkable mechanisms of directed assembly. Here, we report that amyloid fibrils ... -
Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis
(Society for Neuroscience, 2010-11)Despite the progress of the past two decades, the cause of Alzheimer's disease (AD) and effective treatments against it remain elusive. The hypothesis that amyloid-β (Aβ) peptides are the primary causative agents of AD ... -
An a priori analytical method for the determination of operating reserve requirements
(Elsevier BV, 2017)© 2016 Elsevier Ltd Power balance is one of the key requirements for reliable power system operation. However, factors, such as net load variability and forecast errors, impose practical limitations on matching the scheduled ... -
An absorbance method for analysis of enzymatic degradation kinetics of poly(ethylene terephthalate) films
(Springer Science and Business Media LLC, 2021)Increased interest in poly(ethylene terephthalate) (PET)-degrading enzymes (PETases) have generated efforts to find mutants with improved catalytic activity and thermostability. Here, we present a simple and fast method ... -
An accelerator facility for intermediate energy proton irradiation and testing of nuclear materials
(Elsevier BV, 2021)© 2020 The bulk irradiation of materials with 10–30 MeV protons promises to advance the study of radiation damage for fission and fusion power plants. Intermediate energy proton beams can now be dedicated to materials ... -
An analysis of condensation errors in multi-group cross section generation for fine-mesh neutron transport calculations
(Elsevier BV, 2018)© 2017 When collapsing multi-group cross sections, a flux separability approximation is often used. This assumes the angular variation of the flux is independent of the energy dependence, which avoids angular dependence ... -
An Analytic Model for Skin Modulus Measurement Via Conformal Piezoelectric Systems
(ASME International, 2015)Copyright © 2015 by ASME. The Young's modulus of human skin is of great interests to dermatology, cutaneous pathology, and cosmetic industry. A wearable, ultrathin, and stretchable device provides a noninvasive approach ... -
An Ankle-Foot Prosthesis for Rock Climbing Augmentation
(Institute of Electrical and Electronics Engineers (IEEE), 2021)This research presents the design and preliminary evaluation of an electromyographically (EMG) controlled 2-degree-of-freedom (DOF) ankle-foot prosthesis designed to enhance rock climbing ability in persons with transtibial ... -
An Application of Collapsing Levels to the Representation Theory of Affine Vertex Algebras
(Oxford University Press (OUP), 2018)© 2018 The Author(s). Published by Oxford University Press. All rights reserved. We discover a large class of simple affine vertex algebras Vk (g), associated to basic Lie superalgebras g at non-admissible collapsing levels ... -
An avian cortical circuit for chunking tutor song syllables into simple vocal-motor units
(Springer Science and Business Media LLC, 2020)© 2020, The Author(s). How are brain circuits constructed to achieve complex goals? The brains of young songbirds develop motor circuits that achieve the goal of imitating a specific tutor song to which they are exposed. ... -
An Economist’s Guide to Epidemiology Models of Infectious Disease
(American Economic Association, 2020)© 2020 American Economic Association. All rights reserved. Around mid-March 2020, as the United States and much of the rest of the world was facing an unprecedented health threat in the form of COVID-19, an abrupt shift ... -
An Efficient 1-D Thermal Stratification Model for Pool-Type Sodium-Cooled Fast Reactors
(Informa UK Limited, 2020)© 2020 American Nuclear Society. Investigating thermal stratification in the upper plenum of a sodium fast reactor (SFR) is currently a technology gap in SFR safety analysis. Understanding thermal stratification will promote ... -
An Efficient Algorithm for Dynamic Pricing Using a Graphical Representation
(Wiley, 2020)© 2020 Production and Operations Management Society We study a multi-period, multi-item dynamic pricing problem faced by a retailer. The objective is to maximize the total profit by choosing prices, while satisfying several ... -
An Electronic Force Sensor for Medical Jet Injection
(ASME International, 2019)© 2019 by ASME. In medical jet injection, a narrow fluid drug stream is propelled at high velocity into skin without a needle. Previous studies have shown that the volume delivered is highly dependent on a number of factors. ...
