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Browsing MIT Open Access Articles by Title

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  • Fink, Gerald R.; Vyas, Valmik K.; Barrasa, M. Inmaculada (American Association for the Advancement of Science (AAAS), 2015-04)
    Candida albicans is a pathogenic yeast that causes mucosal and systematic infections with high mortality. The absence of facile molecular genetics has been a major impediment to analysis of pathogenesis. The lack of meiosis ...
  • Weinberg, David Eric; Bartel, David; Fink, Gerald R. (National Academy of Sciences, 2012-01)
    The generation of mature functional RNAs from nascent transcripts requires the precise and coordinated action of numerous RNAs and proteins. One such protein family, the ribonuclease III (RNase III) endonucleases, includes ...
  • Tang, Ruqi; Noh, Hyun Ji; Wang, Dongqing; Sigurdsson, Snaevar; Swofford, Ross; Perloski, Michele; Duxbury, Margaret; Patterson, Edward E.; Albright, Julie; Castelhano, Marta; Auton, Adam; Boyko, Adam R.; Feng, Guoping; Lindblad-Toh, Kerstin; Karlsson, Elinor K. (BioMed Central Ltd, 2014-03)
    Background: Obsessive-compulsive disorder (OCD), a severe mental disease manifested in time-consuming repetition of behaviors, affects 1 to 3% of the human population. While highly heritable, complex genetics has hampered ...
  • Berlijn, Tom; Volja, Dmitri; Ku, Wei (American Physical Society, 2011-02)
    We investigate from first principles the proposed destruction of the controversial eg′ pockets in the Fermi surface of Na[subscript x]CoO[subscript 2] due to Na disorder, by calculating its k-dependent configuration-averaged ...
  • Malani, Ateeque A. A. G.; Raghavanpillai, Anilkumar; Wysong, Ernest B.; Rutledge, Gregory C. (American Physical Society, 2012-10)
    A method is presented for determining the dynamic contact angle at the three-phase contact between a solid, a liquid, and a vapor under an applied force, using molecular simulation. The method is demonstrated using a ...
  • Fernandez, Jose-Maria; Fagnan, David Erik; Lo, Andrew W.; Stein, Roger Mark (American Economic Association, 2013-05)
    Traditional financing sources such as private and public equity may not be ideal for investment projects with low probabilities of success, long time horizons, and large capital requirements. Nevertheless, such projects, ...
  • Burton, Lisa Janelle; Bush, John W. M. (American Institute of Physics, 2012-10)
    We consider the role of flexibility in the weight-bearing characteristics of bodies floating at an interface. Specifically, we develop a theoretical model for a two-dimensional thin floating plate that yields the maximum ...
  • Miller, Amalia R.; Tucker, Catherine Elizabeth (University of Chicago Press, 2011-04)
    Electronic medical records (EMRs) facilitate fast and accurate access to patient records, which could improve diagnosis and patient monitoring. Using a 12-year county-level panel, we find that a 10 percent increase in ...
  • Cao, Charles; Chen, Yong; Liang, Bing; Lo, Andrew W. (Elsevier, 2013-04)
    We explore a new dimension of fund managers' timing ability by examining whether they can time market liquidity through adjusting their portfolios' market exposure as aggregate liquidity conditions change. Using a large ...
  • Frisch, P.; Heerikhuisen, Jacob; Pogorelov, Nikolai V.; DeMajistre, R.; Crew, Geoffrey B.; Funsten, H. O.; Janzen, Paul H.; McComas, David J.; Mobius, Eberhard; Mueller, Hans-Reinhard; Reisenfeld, Daniel Brett; Schwadron, Nathan A.; Slavin, Jonathan D.; Zank, Gary Paul (Institute of Physics/American Astronomical Society, 2010-08)
    The Interstellar Boundary Explorer (IBEX) spacecraft is providing the first all-sky maps of the energetic neutral atoms (ENAs) produced by charge exchange between interstellar neutral Ho atoms and heliospheric solar wind ...
  • Agler, Caryline; Nielsen, Dahlia M.; Urkasemsin, Ganokon; Singleton, Andrew; Tonomura, Noriko; Sigurdsson, Snaevar; Tang, Ruqi; Linder, Keith; Arepalli, Sampath; Hernandez, Dena; Lindblad-Toh, Kerstin; van de Leemput, Joyce; Motsinger-Reif, Alison; O'Brien, Dennis P.; Bell, Jerold; Harris, Tonya; Steinberg, Steven; Olby, Natasha J. (Public Library of Science, 2014-02)
    Old English Sheepdogs and Gordon Setters suffer from a juvenile onset, autosomal recessive form of canine hereditary ataxia primarily affecting the Purkinje neuron of the cerebellar cortex. The clinical and histological ...
  • Lashkari, Nima; Van Raamsdonk, Mark (Springer Berlin Heidelberg, 2016-04)
    In quantum information theory, Fisher Information is a natural metric on the space of perturbations to a density matrix, defined by calculating the relative entropy with the unperturbed state at quadratic order in ...
  • Li, Nan (Springer US, 2013-09)
    We study the problem of expanding the product of two Stanley symmetric functions F[subscript w]⋅F[subscript u] into Stanley symmetric functions in some natural way. Our approach is to consider a Stanley symmetric function ...
  • Naseer, Usman (Springer Berlin Heidelberg, 2015-10)
    We provide the canonical formulation of double field theory. It is shown that this dynamics is subject to primary and secondary constraints. The Poisson bracket algebra of secondary constraints is shown to close on-shell ...
  • Kleiman, Steven L.; Vidal Martins, Renato (Springer, 2009-04)
    We give re fined statements and modern proofs of Rosenlicht's re- sults about the canonical model C′ of an arbitrary complete integral curve C. Notably, we prove that C and C′ are birationally equivalent if and only if ...
  • Ehinger, Krista A.; Oliva, Aude (Cognitive Science Society, Inc., 2011-07)
    When recognizing or depicting objects, people show a preference for particular “canonical” views. Are there similar preferences for particular views of scenes? We investigated this question using panoramic images, which show ...
  • Burgess, Robin; Donaldson, David John (2010-05)
    A weakening dependence on rain-fed agriculture has been a hallmark of the economic transformation of countries throughout history. Rural citizens in developing countries today, however, remain highly exposed to ...
  • Sheshadri, Aditi; Plumb, R. Alan; Domeisen, Daniela I. V. (American Meteorological Society, 2014-02)
    The authors test the hypothesis that recent observed trends in surface westerlies in the Southern Hemisphere are directly consequent on observed trends in the timing of stratospheric final warming events. The analysis ...
  • Vanderploeg, Eric J.; Grodzinsky, Alan J. (Elsevier Ltd., 2009-05)
    It is well understood that proper joint kinematics and loading are important factors in maintaining the health of the articular cartilage of the knee. This state of normal, physiologic loading facilitates a balance between ...
  • Datar, Ram; Kim, Seonghwan; Jeon, Sangmin; Hesketh, Peter; Manalis, Scott R.; Boisen, Anja; Thundat, Thomas (Cambridge University Press, 2009-06)
    Cantilever sensors have attracted considerable attention over the last decade because of their potential as a highly sensitive sensor platform for high throughput and multiplexed detection of proteins and nucleic acids. A ...
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