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Browsing MIT Open Access Articles by Title

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  • Wongpiromsarn, Tichakorn; Frazzoli, Emilio (Institute of Electrical and Electronics Engineers (IEEE), 2012-12)
    We consider the synthesis of control policies for probabilistic systems, modeled by Markov decision processes, operating in partially known environments with temporal logic specifications. The environment is modeled by a ...
  • Yuan, Haidong (Institute of Electrical and Electronics Engineers, 2010-01)
    In this article we study the control of single spin in Markovian environment. Given an initial state, we compute all the possible states to which the spin can be driven at arbitrary time, under the assumption that fast ...
  • Lee, Seung Jae; McCormick, Michael S.; Lippard, Stephen J.; Cho, Uhn-Soo (Nature Publishing Group, 2013-02)
    Methanotrophs consume methane as their major carbon source and have an essential role in the global carbon cycle by limiting escape of this greenhouse gas to the atmosphere. These bacteria oxidize methane to methanol by ...
  • Lee, Mary E.; Baker, Tania; Sauer, Robert T. (Elsevier, 2010-04)
    ClpP is a self-compartmentalized protease, which has very limited degradation activity unless it associates with ClpX to form ClpXP or with ClpA to form ClpAP. Here, we show that ClpX binding stimulates ClpP cleavage of ...
  • Young, Richard A.; Young, Richard A. (Elsevier B.V., 2011-03)
    Embryonic stem cells and induced pluripotent stem cells hold great promise for regenerative medicine. These cells can be propagated in culture in an undifferentiated state but can be induced to differentiate into specialized ...
  • Maldonado, Roberto A.; Soriano, Michelle A.; Perdomo, L. Carolina; Sigrist, Kirsten; Irvine, Darrell J.; Decker, Thomas; Glimcher, Laurie H. (Rockefeller University Press, 2009)
    The antigen recognition interface formed by T helper precursors (Thps) and antigen-presenting cells (APCs), called the immunological synapse (IS), includes receptors and signaling molecules necessary for Thp activation and ...
  • Attner, Michelle Andrea; Amon, Angelika B. (American Society for Cell Biology, 2012-06)
    The mitotic exit network (MEN) is an essential GTPase signaling pathway that triggers exit from mitosis in budding yeast. We show here that during meiosis, the MEN is dispensable for exit from meiosis I but contributes to ...
  • Merrikh, Houra (John Wiley & Sons, Inc., 2011-09)
    Proper coordination of DNA replication with cell growth and division is critical for production of viable progeny. In bacteria, coordination of DNA replication with cell growth is generally achieved by controlling activity ...
  • Wu, Chia-Yung; Rolfe, Philip Alexander; Gifford, David K.; Fink, Gerald R. (Public Library of Science, 2010-11)
    Cell size increases significantly with increasing ploidy. Differences in cell size and ploidy are associated with alterations in gene expression, although no direct connection has been made between cell size and transcription. ...
  • Landsman, Alexandra S.; Slotine, Jean-Jacques E. (American Physical Society, 2012-10)
    Understanding synchronous and traveling-wave oscillations, particularly as they relate to transitions between different types of behavior, is a central problem in modeling biological systems. Here, we address this problem ...
  • Andalman, Aaron S.; Foerster, Jakob N.; Fee, Michale S. (Public Library of Science, 2011-09)
    Learned motor behaviors require descending forebrain control to be coordinated with midbrain and brainstem motor systems. In songbirds, such as the zebra finch, regular breathing is controlled by brainstem centers, but ...
  • McIver, J. W.; Hsieh, David; Steinberg, Hadar; Jarillo-Herrero, Pablo; Gedik, Nuh (Nature Publishing Group, 2011-12)
    Three-dimensional topological insulators (1-3) represent a new quantum phase of matter with spin-polarized surface states (4,5) that are protected from backscattering. The static electronic properties of these surface ...
  • Prabhat, Naveen; Buongiorno, Jacopo; Hu, Lin-Wen (American Scientific Publishers, 2012-06)
    The nanofluid literature contains many claims of anomalous convective heat transfer enhancement in both turbulent and laminar flow. To put such claims to the test, we have performed a critical detailed analysis of the ...
  • Lobel, Ilan; Ozdaglar, Asuman E. (Institute of Electrical and Electronics Engineers, 2009-03)
    We consider the problem of cooperatively minimizing the sum of convex functions, where the functions represent local objective functions of the agents. We assume that each agent has information about his local function, ...
  • Marzouk, Youssef M.; Schlegel, Fabrice; Ghoniem, Ahmed F. (Society for Industrial and Applied Mathematics, 2009-06)
    We study the convergence characteristics of two algebraic kernels used in vortex calculations: the Rosenhead–Moore kernel, which is a low-order kernel, and the Winckelmans–Leonard kernel, which is a high-order kernel. To ...
  • Poonen, Bjorn; Lagarias, Jeffrey C.; Wright, Margaret H. (Society for Industrial and Applied Mathematics, 2012-05)
    The Nelder--Mead algorithm, a longstanding direct search method for unconstrained optimization published in 1965, is designed to minimize a scalar-valued function $f$ of $n$ real variables using only function values, without ...
  • Kluberg, Lionel J.; McEneaney, William M. (Society for Industrial and Applied Mathematics, 2009-12)
    In previous work of the first author and others, max-plus methods have been explored for solution of first-order, nonlinear Hamilton–Jacobi–Bellman partial differential equations (HJB PDEs) and corresponding nonlinear ...
  • Yu, Huizhen; Bertsekas, Dimitri P. (Institute of Electrical and Electronics Engineers, 2009-07)
    We consider finite-state Markov decision processes, and prove convergence and rate of convergence results for certain least squares policy evaluation algorithms of the type known as LSPE(lambda ). These are temporal ...
  • Olshevsky, Alexander; Tsitsiklis, John N. (Society for Industrial and Applied Mathematics, 2009-02)
    We study the convergence speed of distributed iterative algorithms for the consensus and averaging problems, with emphasis on the latter. We first consider the case of a fixed communication topology. We show that a simple ...
  • Regev, Aviv; Chen, Ying-Lien; Konieczka, Jay H.; Springer, Deborah J.; Bowen, Samantha E.; Zhang, Jing; Silao, Fitz Gerald S.; Bungay, Alice Alma C.; Bigol, Ursela G.; Nicolas, Marilou G.; Abraham, Soman N.; Thompson, Dawn A.; Heitman, Joseph (Genetics Society of America, The, 2012-06)
    Candida glabrata is an emerging human fungal pathogen that is frequently drug tolerant, resulting in difficulties in treatment and a higher mortality in immunocompromised patients. The calcium-activated protein phosphatase ...
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