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Browsing MIT Open Access Articles by Title

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  • Bond, Bradley N.; Mahmood, Zohaib; Li, Yan; Sredojevic, Ranko; Megretski, Alexandre; Stojanovic, Vladimir Marko; Avniel, Yehuda B.; Daniel, Luca (Institute of Electrical and Electronics Engineers (IEEE), 2009-12)
    This paper presents a system identification technique for generating stable compact models of typical analog circuit blocks in radio frequency systems. The identification procedure is based on minimizing the model error ...
  • Bond, Bradley N.; Mahmood, Zohaib; Li, Yan; Sredojevic, Ranko; Megretski, Alexandre; Stojanovic, Vladimir Marko; Avniel, Yehuda B.; Daniel, Luca (Institute of Electrical and Electronics Engineers, 2010-08)
    This paper presents a system identification technique for generating stable compact models of typical analog circuit blocks in radio frequency systems. The identification procedure is based on minimizing the model error ...
  • Shields, Michael W. (Institute of Electrical and Electronics Engineers, 2009-06)
    A new compact range with a state-of-the-art instrumentation system was installed at Lincoln Laboratory and is currently in use. This paper describes the chamber with varied-height absorber, the rolled-edge reflector and ...
  • Byun, Hyunil; Sander, Michelle Yen-Ling; Motamedi, Ali R.; Shen, Hanfei M.; Petrich, Gale S.; Kolodziejski, Leslie A.; Ippen, Erich P.; Kaertner, Franz X. (Optical Society of America, 2010-10)
    We demonstrate a high-repetition-rate soliton fiber laser that is based on highly-doped anomalously-dispersive erbium-doped fiber. By splicing an 11-mm single mode fiber to the erbium-doped fiber, thermal damage of the ...
  • Tyurikov, Dmitry; Shewmon, Ruth; Benedick, Andrew J.; Kaertner, Franz X.; Gubin, Mikhail; Chuang, Issac L. (Optical Society of America, 2009-07)
    A compact optical clock and frequency comb system is presented, based on a 1 GHz octave spanning Ti:sapphire laser referenced to the F2[superscript(2)](P(7),v[subscript 3]) optical transition in methane at 3.39 μm. The ...
  • Bessuille, J.; Brown, P.; Carbajo, S.; Dolgashev, V.; Lin, H.; Murari, K.; Resta, G.; Tantawi, S.; Zapata, L. E.; Graves, William S.; Hong, Kyung-Han; Ihloff, Ernest E.; Khaykovich, Boris; Nanni, Emilio Alessandro; Kaertner, Franz X.; Moncton, David E. (American Physical Society, 2014-12)
    A design for a compact x-ray light source (CXLS) with flux and brilliance orders of magnitude beyond existing laboratory scale sources is presented. The source is based on inverse Compton scattering of a high brightness ...
  • Wei, He; Insin, Numpon; Lee, Jungmin; Han, Hee-Sun; Liu, Wenhao; Bawendi, Moungi G.; Cordero Hernandez, Jose M. (American Institute of Physics (AIP), 2011-12)
    The potential of superparamagnetic iron oxide nanoparticles (SPIONs) in various biomedical applications, including magnetic resonance imaging (MRI), sensing, and drug delivery, requires that their surface be derivatized ...
  • Wei, He; Chen, Ou; Bawendi, Moungi G.; Bruns, Oliver Thomas (Royal Society of Chemistry, The, 2012-10)
    We have recently developed compact and water-soluble zwitterionic dopamine sulfonate (ZDS) ligand coated superparamagnetic iron oxide nanoparticles (SPIONs) for use in various biomedical applications. The defining ...
  • Cui, Liang; Ye, Wenjie; Wishnok, John S.; Taghizadeh, Koli; Dedon, Peter C.; Prestwich, Erin; Tannenbaum, Steven Robert (American Chemical Society (ACS), 2012-11)
    Oxidative damage to DNA has many origins, including irradiation, inflammation, and oxidative stress, but the chemistries are not the same. The most oxidizable base in DNA is 2-deoxyguanosine (dG), and the primary oxidation ...
  • Adiconis, Xian; Borges-Rivera, Diego; Satija, Rahul; DeLuca, David S; Busby, Michele A; Berlin, Aaron M; Sivachenko, Andrey; Thompson, Dawn Anne; Wysoker, Alec; Fennell, Timothy; Gnirke, Andreas; Pochet, Nathalie; Regev, Aviv; Levin, Joshua Z (Nature Publishing Group, 2013-05)
    RNA-seq is an effective method for studying the transcriptome, but it can be difficult to apply to scarce or degraded RNA from fixed clinical samples, rare cell populations or cadavers. Recent studies have proposed several ...
  • Adiconis, Xian; Borges-Rivera, Diego; Satija, Rahul; DeLuca, David S; Busby, Michele A; Berlin, Aaron M; Sivachenko, Andrey; Thompson, Dawn Anne; Wysoker, Alec; Fennell, Timothy; Gnirke, Andreas; Pochet, Nathalie; Regev, Aviv; Levin, Joshua Z (Nature Publishing Group, 2013-05)
    RNA-seq is an effective method for studying the transcriptome, but it can be difficult to apply to scarce or degraded RNA from fixed clinical samples, rare cell populations or cadavers. Recent studies have proposed several ...
  • Ghiviriga, Ion; Dancel, Christine; Kodira, Chinnappa D.; Desany, Brian; Affourtit, Jason P.; Abeel, Thomas; Gevers, Dirk; Birren, Bruce W.; Godfrey, Paul A.; Desjardins, Christopher A.; Holder, Jason W.; DeBono, Tony; Ulrich, Jil; Zucker, Jeremy; Zeng, Qiandong; Leach, Alex L. B.; Sinskey, Anthony J. (Public Library of Science, 2011-09)
    The Actinomycetales bacteria Rhodococcus opacus PD630 and Rhodococcus jostii RHA1 bioconvert a diverse range of organic substrates through lipid biosynthesis into large quantities of energy-rich triacylglycerols (TAGs). ...
  • Bourgeois, Florence T.; Murthy, Srinivas; Mandl, Kenneth D. (Public Library of Science, 2012-01)
    Background The $1.1 billion investment in comparative effectiveness research will reshape the evidence-base supporting decisions about treatment effectiveness, safety, and cost. Defining the current prevalence and ...
  • Agarwal, Abhinav; Ng, Man Cheuk; Mithal, Arvind (Institute of Electrical and Electronics Engineers (IEEE), 2010-07)
    Using the example of a Reed-Solomon decoder, we provide insights into what type of hardware structures are needed to be generated to achieve specific performance targets. Due to the presence of run-time dependencies, ...
  • Regev, Aviv; Kellis, Manolis; Lin, Michael F. (American Association for the Advancement of Science (AAAS), 2011-04)
    The fission yeast clade—comprising Schizosaccharomyces pombe, S. octosporus, S. cryophilus, and S. japonicus—occupies the basal branch of Ascomycete fungi and is an important model of eukaryote biology. A comparative ...
  • Holder, Jason W. (Public Library of Science, 2011-10)
    Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, ...
  • Lutfalla, Georges; Roest Crollius, Hugues; Stange-Thomann, Nicole; Jaillon, Olivier; Mogensen, Knud; Monneron, Daniele (BioMed Central Ltd, 2003-07)
    Background: The high degree of sequence conservation between coding regions in fish and mammals can be exploited to identify genes in mammalian genomes by comparison with the sequence of similar genes in fish. Conversely, ...
  • Palmer, Kelli L.; Godfrey, Paul; Griggs, Allison; Kos, Veronica N.; Zucker, Jeremy; Desjardins, Christopher; Cerqueira, Gustavo; Gevers, Dirk; Walker, Suzanne; Wortman, Jennifer; Feldgarden, Michael; Haas, Brian; Birren, Bruce W.; Gilmore, Michael S. (American Society for Microbiology, 2012-02)
    The enterococci are Gram-positive lactic acid bacteria that inhabit the gastrointestinal tracts of diverse hosts. However, Enterococcus faecium and E. faecalis have emerged as leading causes of multidrug-resistant ...
  • Rajapakse, Jagath; Pooja; Chen, Chunxi; Ho, Sy-Loi (Institute of Electrical and Electronics Engineers, 2009-07)
    his article describes a workflow for identifying conserved patterns in noncoding regions of vertebrate genomes, with an intention of investigating possible functions of the conserved regions. The annotations of genomes are ...
  • Zhang, GuangJun; Hoersch, Sebastian; Amsterdam, Adam; Whittaker, Charles A.; Beert, Eline; Catchen, Julian M.; Postlethwait, John H.; Legius, Eric; Farrington, Sarah M.; Hopkins, Nancy H.; Lees, Jacqueline (Public Library of Science, 2013-08)
    The identification of cancer drivers is a major goal of current cancer research. Finding driver genes within large chromosomal events is especially challenging because such alterations encompass many genes. Previously, we ...
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