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Browsing MIT Open Access Articles by Title

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  • Klattenhoff, Carla A.; Scheuermann, Johanna C.; Surface, Lauren E.; Bradley, Robert K.; Fields, Paul A.; Steinhauser, Matthew L.; Ding, Huiming; Torrey, Lillian; Haas, Simon; Abo, Ryan; Tabebordbar, Mohammadsharif; Lee, Richard T.; Burge, Christopher B.; Butty, Vincent; Boyer, Laurie; Klattenhoff, Carla A.; Scheuermann, Johanna C.; Surface, Lauren E.; Bradley, Robert K.; Fields, Paul A.; Burge, Christopher B. (Elsevier, 2013-01)
    Long noncoding RNAs (lncRNAs) are often expressed in a development-specific manner, yet little is known about their roles in lineage commitment. Here, we identified Braveheart (Bvht), a heart-associated lncRNA in mouse. ...
  • Lander, Eric Steven (Massachusetts Medical Society, 2015-07)
    Fifty years ago, microbiologists sparked the recombinant-DNA revolution with the discovery that bacteria have innate immune systems based on restriction enzymes. These enzymes bind and cut invading viral genomes at specific ...
  • Hatchi, Elodie; Skourti-Stathaki, Konstantina; Ventz, Steffen; Pinello, Luca; Yen, Angela; Kamieniarz-Gdula, Kinga; Dimitrov, Stoil; Pathania, Shailja; McKinney, Kristine M.; Kellis, Manolis; Hill, Sarah J.; Parmigiani, Giovanni; Proudfoot, Nicholas J.; Livingston, David M.; Eaton, Matthew Lucas (Elsevier, 2015-02)
    The mechanisms contributing to transcription-associated genomic instability are both complex and incompletely understood. Although R-loops are normal transcriptional intermediates, they are also associated with genomic ...
  • Merok, Joshua R.; Sherley, James L. (Hindawi Publishing Corporation, 2001)
    Here we have reviewed the conventional definitions and fundamental characteristics of the two basic types of stem cells, embryonic stem cells (ESCs) and somatic stem cells (SSCs). By taking into account the often-overlooked ...
  • Shih, Chih-Jen; Wang, Qing Hua; Lin, Shangchao; Park, Kyoo Chul; Jin, Zhong; Strano, Michael S.; Blankschtein, Daniel (American Physical Society, 2012-10)
    We develop a theory to model the van der Waals interactions between liquid and graphene, including quantifying the wetting behavior of a graphene-coated surface. Molecular dynamics simulations and contact angle measurements ...
  • Lu, Bin; Piner, Edwin L.; Palacios, Tomas (Institute of Electrical and Electronics Engineers (IEEE), 2010-08)
    AlGaN/GaN high electron mobility transistors (HEMTs) grown on Si substrates have attracted a great interest for power electronics applications. Despite the low cost of the Si substrate, the breakdown voltage (V[subscript ...
  • Dillard, Colin R.; Lin, Xi; Kastner, Marc A.; Pfeiffer, L. N.; West, K. W. (Elsevier, 2012-07)
    The integer and fractional quantum Hall states are known to breakdown at high dc bias, exhibiting deviation from the ideal incompressible behavior. We measure breakdown of the ν=2, 3, 4, 5 integer and the ν=4/3 and 5/3 ...
  • Udrea, Florin; Napoli, Ettore; Wang, Han (Institute of Electrical and Electronics Engineers, 2009-11)
    An analytical model for the electric field and the breakdown voltage (BV) of an unbalanced superjunction (SJ) device is presented in this paper. The analytical technique uses a superposition approach treating the asymmetric ...
  • Preminger, Omer (MIT Press, 2009-10)
    In this article, I propose a novel way to distinguish between agreement and clitic doubling. The innovation lies in examining what happens when the relation between the relevant agreement morphology and the full noun phrase ...
  • Lutomirski, Andrew Michael; Gosset, David Nicholas; Hassidim, Avinatan; Farhi, Edward; Shor, Peter W.; Kelner, Jonathan Adam; Aaronson, Scott (Institute for Computer Science, 2010-01)
    Public-key quantum money is a cryptographic protocol in which a bank can create quantum states which anyone can verify but no one except possibly the bank can clone or forge. There are no secure public-key quantum money ...
  • Villalon, Rachelle; Lieberman, Henry A.; Sass, Larry (Association for Computing Machinery (ACM), 2009-04)
    Architectural designs are not just collections of 3D objects. Architects have both high-level aesthetic design intent, and intent for the functionality of the building; these must eventually translate into real-world ...
  • Kaufman-Halman, Tali; Litsyn, Simon; Xie, Ning (Society for Industrial and Applied Mathematics, 2010-02)
    For Boolean functions that are $\epsilon$-far from the set of linear functions, we study the lower bound on the rejection probability (denoted by REJ(epsilon) of the linearity test suggested by Blum, Luby, and Rubinfeld ...
  • Brimhall, Nicole; Manthena, Rajakumar Varma; Menon, Rajesh; Andrew, Trisha Lionel (American Physical Society (APS), 2011-11)
    By saturating a photochromic transition with a nodal illumination (wavelength, λ), one isomeric form of a small molecule is spatially localized to a region smaller than the far-field diffraction limit. A selective oxidation ...
  • Mandl, Kenneth D.; Brownstein, John S.; Dasgupta, Nabarun (Public Library of Science, 2009-11)
    Background Historical studies of news media have suggested an association between reporting and increased drug abuse. Period effects for substance use have been documented for different classes of legal and illicit ...
  • Zuckerman Sivan, Ezra W; Sgourev, Stoyan (Sage Publications, 2011-03)
    This paper strengthens the basis for a key claim of contemporary economic sociology — that strong ties among capitalists cannot be reduced to rational considerations. Support for this claim has been limited by reliance on ...
  • Liu, Ping; Zhang, Yong-Wei; Li, Ju (The Chinese Society of Theoretical and Applied Mechanics; Institute of Mechanics, Chinese Academy of Sciences, 2012-12)
    We present our theoretical analysis and coarsegrained molecular dynamics (CGMD) simulation results to describe the mechanics of breakup of spherical vesicles driven by changes in spontaneous curvature. Systematic CGMD ...
  • Christen, Stefan; Lorendeau, Doriane; Schmieder, Roberta; Broekaert, Dorien; Metzger, Kristine; Veys, Koen; Elia, Ilaria; Buescher, Joerg Martin; Orth, Martin Franz; Grünewald, Thomas Georg Philipp; De Bock, Katrien; Fendt, Sarah-Maria; Davidson, Shawn Michael (Elsevier, 2016-10)
    Cellular proliferation depends on refilling the tricarboxylic acid (TCA) cycle to support biomass production (anaplerosis). The two major anaplerotic pathways in cells are pyruvate conversion to oxaloacetate via pyruvate ...
  • Suntharalingam, Kogularamanan; Lin, Wei; Johnstone, Timothy; Bruno, Peter Michael; Zheng, Yaorong; Hemann, Michael; Lippard, Stephen J. (American Chemical Society (ACS), 2014-09)
    The effect of a newly developed osmium(VI) nitrido complex, 1, on breast cancer stem cells (CSCs) is reported. The complex displays selective toxicity for HMLER breast cancer cells enriched with CD44-positive, CSC-like ...
  • Hasdeo, Eddwi H.; Nugraha, Ahmad R. T.; Saito, Riichiro; Dresselhaus, Mildred (American Physical Society, 2014-12)
    Excitation of electron-hole pairs in the vicinity of the Dirac cone by the Coulomb interaction gives rise to an asymmetric Breit-Wigner-Fano line shape in the phonon Raman spectra in graphene. This asymmetric line shape ...
  • Chen, C. D.; Patel, P. K.; Hey, D. S.; Mackinnon, A. J.; Key, M. H.; Akli, K. U.; Bartal, T.; Beg, F. N.; Chawla, S.; Chen, H.; Freeman, R. R.; Higginson, D. P.; Link, A.; Ma, T. Y.; MacPhee, A. G.; Stephens, R. B.; Van Woerkom, L. D.; Westover, B.; Porkolab, Miklos (American Institute of Physics, 2009-08)
    The Bremsstrahlung and K-shell emission from 1×1×1 mm[superscript 3] planar targets irradiated by a short-pulse 3×10[superscript 18]–8×10[superscript 19] W/cm[superscript 2] laser were measured. The Bremsstrahlung was ...
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