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Browsing MIT Open Access Articles by Title

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  • Brereton, Justin; Farid, Amelia; Karnib, Maryam; Marple, Gary; Quenon, Alex; Tefera, Akula (Electronic Journal of Combinatorics, 2011-06)
    This paper focuses on two binomial identities. The proofs illustrate the power and elegance in enumerative/algebraic combinatorial arguments, modern machine-assisted techniques of Wilf-Zeilberger and the classical tools ...
  • Bains, William; Seager, Sara (Mary Ann Liebert, Inc., 2012-03)
    Redox chemistry is central to life on Earth. It is well known that life uses redox chemistry to capture energy from environmental chemical energy gradients. Here, we propose that a second use of redox chemistry, related ...
  • Shen, Wenqing; Tian, Tao; Liao, Bolin; Zebarjadi, Mona (American Physical Society, 2014-08)
    The possibility of designing core-shell nanoparticles that are “invisible” to the conduction electrons has been demonstrated recently. A total scattering cross section smaller than 0.01% of the physical cross section was ...
  • Bayati, Mohsen; Gamarnik, David; Tetali, Prasad (Association for Computing Machinery, 2010-06)
    We establish the existence of free energy limits for several sparse random hypergraph models corresponding to certain combinatorial models on Erd¨os-R´enyi graph G(N, c/N) and random r-regular graph G(N, r). For a variety ...
  • Dolatshahi-Pirouz, Alireza; Nikkhah, Mehdi; Gaharwar, Akhilesh K.; Hashmi, Basma; Guermani, Enrico; Aliabadi, Hamed; Camci-Unal, Gulden; Ferrante, Thomas; Foss, Morten; Ingber, Donald E.; Khademhosseini, Ali (Nature Publishing Group, 2014-01)
    Development of three dimensional (3D) microenvironments that direct stem cell differentiation into functional cell types remains a major challenge in the field of regenerative medicine. Here, we describe a new platform to ...
  • Mei, Ying; Saha, Krishanu; Bogatyrev, Said R.; Yang, Jing; Hook, Andrew L.; Kalcioglu, Zeynep Ilke; Cho, Seung-Woo; Mitalipova, Maisam; Pyzocha, Neena; Rojas, Fredrick P.; Van Vliet, Krystyn J.; Davies, Martyn C.; Alexander, Morgan R.; Langer, Robert; Jaenisch, Rudolf; Anderson, Daniel G. (Nature Publishing Group, 2010-08)
    Both human embryonic stem cells and induced pluripotent stem cells can self-renew indefinitely in culture; however, present methods to clonally grow them are inefficient and poorly defined for genetic manipulation and ...
  • Hook, Andrew L; Chang, Chien-Yi; Yang, Jing; Luckett, Jeni; Cockayne, Alan; Atkinson, Steve; Mei, Ying; Bayston, Roger; Irvine, Derek J; Langer, Robert; Williams, Paul; Davies, Martyn C; Alexander, Morgan R; Anderson, Daniel Griffith (Nature Publishing Group, 2012-08)
    Bacterial attachment and subsequent biofilm formation pose key challenges to the optimal performance of medical devices. In this study, we determined the attachment of selected bacterial species to hundreds of polymeric ...
  • Zou, Ruiyang; Zhou, Kang; Stephanopoulos, Gregory; Too, Heng Phon (Public Library of Science, 2013-11)
    The ability to assemble multiple fragments of DNA into a plasmid in a single step is invaluable to studies in metabolic engineering and synthetic biology. Using phosphorothioate chemistry for high efficiency and site ...
  • Reticker-Flynn, Nathan E.; Malta, David F. Braga; Winslow, Monte M.; Underhill, Gregory H.; Hynes, Richard O.; Jacks, Tyler E.; Bhatia, Sangeeta N.; Lamar, John Michael; Xu, Mary Jue (Nature Publishing Group, 2012-10)
    Extracellular matrix interactions have essential roles in normal physiology and many pathological processes. Although the importance of extracellular matrix interactions in metastasis is well documented, systematic approaches ...
  • Sun, Shuo; Wang, Ming; Knupp, Sarah A.; Soto-Feliciano, Yadira; Hu, Xiao; Kaplan, David L.; Langer, Robert; Anderson, Daniel G.; Xu, Qiaobing (American Chemical Society, 2012-01)
    A combinatorial library of lipidoids was constructed and studied for in vitro gene delivery. The library of lipidoids was synthesized by reacting commercially available amines with lipophilic acrylates, acrylamides, or ...
  • Abdolhosseini Qomi, Mohammad; Krakowiak, Konrad J.; Bauchy, M.; Stewart, K. L.; Shahsavari, Setareh; Jagannathan, D.; Brommer, Dieter Bresnan; Baronnet, A.; Buehler, Markus J.; Yip, S.; Ulm, Franz-Josef; Van Vliet, Krystyn J.; Pellenq, Roland Jm (Nature Publishing Group, 2014-09)
    Despite its ubiquitous presence in the built environment, concrete’s molecular-level properties are only recently being explored using experimental and simulation studies. Increasing societal concerns about concrete’s ...
  • Ram, Oren; Goren, Alon; Amit, Ido; Shoresh, Noam; Yosef, Nir; Ernst, Jason; Kellis, Manolis; Issner, Robbyn; Durham, Timothy; Zhang, Xiaolan; Donaghey, Julie; Epstein, Charles B.; Regev, Aviv; Bernstein, Bradley E.; Gymrek, Melissa A.; Coyne, Michael J. (Elsevier, 2011-12)
    Hundreds of chromatin regulators (CRs) control chromatin structure and function by catalyzing and binding histone modifications, yet the rules governing these key processes remain obscure. Here, we present a systematic ...
  • Avron, Haim; Chen, Doron; Shklarski, Gil; Toledo, Sivan (Society for Industrial and Applied Mathematics, 2009-06)
    We present a new preconditioner for linear systems arising from finite-element discretizations of scalar elliptic partial differential equations (PDE's). The solver splits the collection $\{K_{e}\}$ of element matrices ...
  • Siegwart, Daniel; Whitehead, Kathryn Ann; Nuhn, Lutz; Sahay, Gaurav; Cheng, Hao; Jiang, Shan; Ma, Minglin; Lytton-Jean, Abigail K. R.; Vegas, Arturo; Fenton, Patrick; Levins, Christopher G.; Love, Kevin T.; Lee, Haeshin; Cortez, Christina; Collins, Sean P.; Li, Ying Fei; Jang, Janice; Querbes, William; Zurenko, Christopher; Novobrantseva, Tatiana; Langer, Robert; Anderson, Daniel G. (National Academy of Sciences (U.S.), 2011-08)
    Analogous to an assembly line, we employed a modular design for the high-throughput study of 1,536 structurally distinct nanoparticles with cationic cores and variable shells. This enabled elucidation of complexation, ...
  • Formaggio, Joseph A.; Miller, Melanie L.; Monreal, B.; Monroe, Jocelyn; Solomon-Oblath, Noah; Ott, R. A.; Sonley, T. J. (American Physical Society, 2013-08)
    We report results from a combined analysis of solar neutrino data from all phases of the Sudbury Neutrino Observatory (SNO). By exploiting particle identification information obtained from the proportional counters installed ...
  • Kang, Jeon Woong; Lue, Niyom; Kong, Chae-Ryon; Barman, Ishan; Dingari, Narahara Chari; Dasari, Ramachandra Rao; Feld, Michael S.; Goldfless, Stephen Jacob; Niles, Jacquin (Optical Society of America, 2011-08)
    We have developed a novel multimodal microscopy system that incorporates confocal Raman, confocal reflectance, and quantitative phase microscopy (QPM) into a single imaging entity. Confocal Raman microscopy provides detailed ...
  • van Wijk, Nick; Watkins, Carol J.; Hageman, Robert J. J.; Sijben, John C. W.; Kamphuis, Patrick G. H. J.; Wurtman, Richard Jay; Broersen, Laus M. (BioMed Central Ltd, 2012-05)
    Background: Folate, vitamin B-12, and vitamin B-6 are essential nutritional components in one-carbon metabolism and are required for methylation capacity. The availability of these vitamins may therefore modify methylation ...
  • Tentner, Andrea R; Lee, Michael; Ostheimer, Gerry J.; Samson, Leona D.; Lauffenburger, Douglas A.; Yaffe, Michael B. (Nature Publishing Group, 2012-01)
    Following DNA damage, cells display complex multi-pathway signaling dynamics that connect cell-cycle arrest and DNA repair in G1, S, or G2/M phase with phenotypic fate decisions made between survival, cell-cycle re-entry ...
  • Figueroa-Feliciano, Enectali; Hertel, Scott Alexander; Leman, Steven W.; McCarthy, Kevin Ahmad; Wikus, Patrick (American Physical Society, 2011-07)
    The CDMS and EDELWEISS collaborations have combined the results of their direct searches for dark matter using cryogenic germanium detectors. The total data set represents 614  kg·days equivalent exposure. A straightforward ...
  • Melas, Ioannis N.; Mitsos, Alexander; Messinis, Dimitris E.; Weiss, Thomas S.; Alexopoulos, Leonidas G. (BioMed Central Ltd., 2011-07)
    Background Signalling pathways are the cornerstone on understanding cell function and predicting cell behavior. Recently, logical models of canonical pathways have been optimised with high-throughput phosphoproteomic ...
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