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Browsing MIT Open Access Articles by Title

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  • Ram, Oren; Goren, Alon; Amit, Ido; Shoresh, Noam; Yosef, Nir; Ernst, Jason; Kellis, Manolis; Issner, Robbyn; Durham, Timothy; Zhang, Xiaolan; Donaghey, Julie; Epstein, Charles B.; Regev, Aviv; Bernstein, Bradley E.; Gymrek, Melissa A.; Coyne, Michael J. (Elsevier, 2011-12)
    Hundreds of chromatin regulators (CRs) control chromatin structure and function by catalyzing and binding histone modifications, yet the rules governing these key processes remain obscure. Here, we present a systematic ...
  • Avron, Haim; Chen, Doron; Shklarski, Gil; Toledo, Sivan (Society for Industrial and Applied Mathematics, 2009-06)
    We present a new preconditioner for linear systems arising from finite-element discretizations of scalar elliptic partial differential equations (PDE's). The solver splits the collection $\{K_{e}\}$ of element matrices ...
  • Siegwart, Daniel; Whitehead, Kathryn Ann; Nuhn, Lutz; Sahay, Gaurav; Cheng, Hao; Jiang, Shan; Ma, Minglin; Lytton-Jean, Abigail K. R.; Vegas, Arturo; Fenton, Patrick; Levins, Christopher G.; Love, Kevin T.; Lee, Haeshin; Cortez, Christina; Collins, Sean P.; Li, Ying Fei; Jang, Janice; Querbes, William; Zurenko, Christopher; Novobrantseva, Tatiana; Langer, Robert; Anderson, Daniel G. (National Academy of Sciences (U.S.), 2011-08)
    Analogous to an assembly line, we employed a modular design for the high-throughput study of 1,536 structurally distinct nanoparticles with cationic cores and variable shells. This enabled elucidation of complexation, ...
  • Formaggio, Joseph A.; Miller, Melanie L.; Monreal, B.; Monroe, Jocelyn; Solomon-Oblath, Noah; Ott, R. A.; Sonley, T. J. (American Physical Society, 2013-08)
    We report results from a combined analysis of solar neutrino data from all phases of the Sudbury Neutrino Observatory (SNO). By exploiting particle identification information obtained from the proportional counters installed ...
  • Kang, Jeon Woong; Lue, Niyom; Kong, Chae-Ryon; Barman, Ishan; Dingari, Narahara Chari; Dasari, Ramachandra Rao; Feld, Michael S.; Goldfless, Stephen Jacob; Niles, Jacquin (Optical Society of America, 2011-08)
    We have developed a novel multimodal microscopy system that incorporates confocal Raman, confocal reflectance, and quantitative phase microscopy (QPM) into a single imaging entity. Confocal Raman microscopy provides detailed ...
  • van Wijk, Nick; Watkins, Carol J.; Hageman, Robert J. J.; Sijben, John C. W.; Kamphuis, Patrick G. H. J.; Wurtman, Richard Jay; Broersen, Laus M. (BioMed Central Ltd, 2012-05)
    Background: Folate, vitamin B-12, and vitamin B-6 are essential nutritional components in one-carbon metabolism and are required for methylation capacity. The availability of these vitamins may therefore modify methylation ...
  • Tentner, Andrea R; Lee, Michael; Ostheimer, Gerry J.; Samson, Leona D.; Lauffenburger, Douglas A.; Yaffe, Michael B. (Nature Publishing Group, 2012-01)
    Following DNA damage, cells display complex multi-pathway signaling dynamics that connect cell-cycle arrest and DNA repair in G1, S, or G2/M phase with phenotypic fate decisions made between survival, cell-cycle re-entry ...
  • Figueroa-Feliciano, Enectali; Hertel, Scott Alexander; Leman, Steven W.; McCarthy, Kevin Ahmad; Wikus, Patrick (American Physical Society, 2011-07)
    The CDMS and EDELWEISS collaborations have combined the results of their direct searches for dark matter using cryogenic germanium detectors. The total data set represents 614  kg·days equivalent exposure. A straightforward ...
  • Melas, Ioannis N.; Mitsos, Alexander; Messinis, Dimitris E.; Weiss, Thomas S.; Alexopoulos, Leonidas G. (BioMed Central Ltd., 2011-07)
    Background Signalling pathways are the cornerstone on understanding cell function and predicting cell behavior. Recently, logical models of canonical pathways have been optimised with high-throughput phosphoproteomic ...
  • Toni, Tina; Tidor, Bruce (Public Library of Science, 2013-03)
    Biological systems are inherently variable, with their dynamics influenced by intrinsic and extrinsic sources. These systems are often only partially characterized, with large uncertainties about specific sources of extrinsic ...
  • Zhu, Rong; Buchwald, Stephen Leffler (Wiley Blackwell, 2012-01)
    An efficient protocol has been developed for the intramolecular oxidative oxyarylation using a Pd[superscript II]-catalyzed tandem oxypalladation/C-H functionalization strategy. This methodology allows rapid access to ...
  • Alver, B.; Bauer, Gerry P.; Bendavid, Joshua L.; Busza, Wit; Butz, Erik M.; Cali, Ivan Amos; Chan, M.; Dutta, V.; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Hahn, Kristian Allan; Kim, Y.; Klute, Markus; Lee, Y.-J.; Li, W.; Luckey, P. David, Jr.; Ma, Teng; Nahn, Steven; Paus, Christoph M. E.; Ralph, Duncan Kelley; Roland, Christof E.; Roland, Gunther M.; Rudolph, Matthew Scott; Stephans, George S. F.; Stockli, Fabian; Sumorok, Konstanty C.; Sung, Kevin Kai Hong; Velicanu, Dragos Alexandru; Wenger, Edward Allen; Wolf, R.; Wyslouch, Boleslaw; Xie, S.; Yang, M.; Yilmaz, Yetkin; Yoon, A. S.; Zanetti, Marco (Elsevier, 2012-02)
    Combined results are reported from searches for the standard model Higgs boson in proton–proton collisions at √s = 7 TeV in five Higgs boson decay modes: γγ, bb, ττ , WW, and ZZ. The explored Higgs boson mass range is ...
  • Apyan, Aram; Bauer, Gerry P.; Bendavid, Joshua L.; Busza, Wit; Butz, Erik M.; Cali, Ivan Amos; Chan, M.; Dutta, V.; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Hahn, Kristian Allan; Kim, Y.; Klute, Markus; Krajczar, Krisztian F.; Li, W.; Luckey, P. David Jr.; Ma, Teng; Nahn, Steven; Paus, Christoph M. E.; Ralph, Duncan Kelley; Roland, Christof E.; Roland, Gunther M.; Rudolph, M.; Stephans, George S. F.; Stockli, Fabian; Sumorok, Konstanty C.; Sung, Kevin Kai Hong; Velicanu, Dragos Alexandru; Wenger, Edward Allen; Wolf, R.; Wyslouch, Boleslaw; Yang, M.; Yilmaz, Yetkin; Yoon, A. S.; Zanetti, Marco (American Physical Society, 2012-12)
    Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5  fb[superscript -1] recorded by the CMS experiment at the LHC ...
  • Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Paus, Christoph M. E. (American Physical Society, 2012-09)
    We combine the results of searches for the standard model (SM) Higgs boson based on the full CDF Run II data set obtained from √s=1.96  TeV pp̅ collisions at the Fermilab Tevatron corresponding to an integrated luminosity ...
  • Taylor, Frank E. (American Physical Society, 2012-08)
    A combined search for the Standard Model Higgs boson with the ATLAS detector at the LHC is presented. The data sets used correspond to integrated luminosities from 4.6  fb[superscript -1] to 4.9  fb[superscript -1] of ...
  • Taylor, Frank E. (Elsevier, 2012-02)
    A combined search for the Standard Model Higgs boson with the ATLAS experiment at the LHC using datasets corresponding to integrated luminosities from 1.04 fb[superscript −1] to 4.9 fb[superscript −1] of pp collisions ...
  • Quinn, David J.; Pivkin, Igor; Wong, Sophie Y.; Chiam, Keng-Hwee; Dao, Ming; Karniadakis, George Em; Suresh, Subra (Springer-Verlag, 2010-12)
    We investigate the biophysical characteristics of healthy human red blood cells (RBCs) traversing microfluidic channels with cross-sectional areas as small as 2.7 × 3 μm. We combine single RBC optical tweezers and flow ...
  • Paus, Christoph M. E.; Bauer, Gerry P.; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Makhoul, K. (American Physical Society, 2010-07)
    We combine results from searches by the CDF and D0 collaborations for a standard model Higgs boson (H) in the process gg-->H-->W+W- in pp̅ collisions at the Fermilab Tevatron Collider at [sqrt]s=1.96  TeV. With 4.8  fb-1 ...
  • Demaine, Erik D.; Iacono, John; Langerman, Stefan; Ozkan, Ozgur (Springer-Verlag, 2013-07)
    We present a general transformation for combining a constant number of binary search tree data structures (BSTs) into a single BST whose running time is within a constant factor of the minimum of any “well-behaved” bound ...
  • Zhang, Congqiang; Chen, Xixian; Zou, Ruiyang; Zhou, Kang; Stephanopoulos, Gregory; Too, Heng-Phon (Public Library of Science, 2013-10)
    Isoprenoids are a large and diverse class of compounds that includes many high value natural products and are thus in great demand. To meet the increasing demand for isoprenoid compounds, metabolic engineering of microbes ...
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