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Browsing MIT Open Access Articles by Title

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  • Clayton, Sophie A; Dutkiewicz, Stephanie; Jahn, Oliver; Hill, Christopher N; Heimbach, Patrick; Follows, Michael J (Copernicus GmbH, 2017-06)
    We present a systematic study of the differences generated by coupling the same ecological-biogeochemical model to a 1°, coarse-resolution, and 1â •6°, eddy-permitting, global ocean circulation model to (a) biogeochemistry ...
  • Monteiro, Fanny Meline; Dutkiewicz, Stephanie; Follows, Michael J. (American Geophysical Union (AGU), 2011-04)
    We interpret the environmental controls on the global ocean diazotroph biogeography in the context of a three-dimensional global model with a self-organizing phytoplankton community. As is observed, the model's total ...
  • O'Connor, Timothy K.; Charkoudian, Louise K.; Docherty, Kathryn M.; Jones, Evan; Kembel, Steven W.; Green, Jessica L.; Bohannan, Brendan J. M.; Bryant, Jessica A.; Morlon, Helene (Public Library of Science, 2015-06)
    Understanding patterns in the distribution and abundance of functional traits across a landscape is of fundamental importance to ecology. Mapping these distributions is particularly challenging for species-rich groups with ...
  • Li, Yin; Rehg, James M.; Hernandez Rivera, Javier (Institute of Electrical and Electronics Engineers (IEEE), 2015-01)
    This work explores the feasibility of using sensors embedded in Google Glass, a head-mounted wearable device, to measure physiological signals of the wearer. In particular, we develop new methods to use Glass’s accelerometer, ...
  • Gevers, Dirk; Pop, Mihai; Schloss, Patrick D.; Huttenhower, Curtis (Public Library of Science, 2012-11)
    Microbes inhabit virtually all sites of the human body, yet we know very little about the role they play in our health. In recent years, there has been increasing interest in studying human-associated microbial communities, ...
  • Hernandez Rivera, Javier; McDuff, Daniel Jonathan; Picard, Rosalind W. (Institute of Electrical and Electronics Engineers (IEEE), 2015-06)
    During recent years a large variety of wearable devices have become commercially available. As these devices are in close contact with the body, they have the potential to capture sensitive and unexpected personal data ...
  • Sarpeshkar, Rahul; Zhak, Serhii M.; Mandal, Soumyajit (Institute of Electrical and Electronics Engineers, 2009-06)
    Fast wideband spectrum analysis is expensive in power and hardware resources. We show that the spectrum-analysis architecture used by the biological cochlea is extremely efficient: analysis time, power and hardware usage ...
  • DeRosa, Frank; Langer, Robert; Fenton, Owen S.; Kauffman, Kevin John; McClellan, Rebecca L; Appel, Eric; Dorkin, Joseph Robert; Tibbitt, Mark W; Langer, Robert S; Anderson, Daniel Griffith (Wiley Blackwell, 2016-02)
    Thousands of human diseases could be treated by selectively controlling the expression of specific proteins in vivo. A new series of alkenyl amino alcohol (AAA) ionizable lipid nanoparticles (LNPs) capable of delivering ...
  • He, Xin; Yassine, Omar; Salama, Khaled N.; Zhang, Xi-Xiang; Savagatrup, Suchol; Schroeder, Vera; Lin, Sibo; He, Maggie; Swager, Timothy M (Wiley Blackwell, 2017-10)
    Carbon monoxide (CO) outcompetes oxygen when binding to the iron center of hemeproteins, leading to a reduction in blood oxygen level and acute poisoning. Harvesting the strong specific interaction between CO and the iron ...
  • Fu, Katherine; Moreno, Diana; Yang, Maria; Wood, Kristin L. (ASME International, 2014-10)
    Bio-inspired design and the broader field of design-by-analogy have been the basis of numerous innovative designs throughout history; yet there remains much to be understood about these practices of design, their underlying ...
  • Artemiadis, Panagiotis; Kyriakopoulos, Kostas J. (Institute of Electrical and Electronics Engineers, 2009-07)
    There is a great effort during the last decade towards building control interfaces for robots that are based on signals measured directly from the human body. In particular electromyographic (EMG) signals from skeletal ...
  • Boyce, Mary Cunningham; Li, Yaning; Ortiz, Christine (American Physical Society, 2012-03)
    Many biological systems possess hierarchical and fractal-like interfaces and joint structures that bear and transmit loads, absorb energy, and accommodate growth, respiration, and/or locomotion. In this paper, an elastic ...
  • England, Grant; Kolle, Mathias; Kim, Philseok; Khan, Mughees; Munoz, Philip; Mazur, Eric; Aizenberg, Joanna (National Academy of Sciences (U.S.), 2014-10)
    Recently, diffraction elements that reverse the color sequence normally observed in planar diffraction gratings have been found in the wing scales of the butterfly Pierella luna. Here, we describe the creation of an ...
  • Zhao, Weian; Cui, Cheryl; Bose, Suman; Guo, Dagang; Shen, Chong; Wong, Wesley P.; Halvorsen, Ken; Farokhzad, Omid C.; Teo, Grace Sock Leng; Phillips, Joseph A.; Dorfman, David M.; Karnik, Rohit; Karp, Jeffrey Michael (National Academy of Sciences (U.S.), 2012-11)
    Capture and isolation of flowing cells and particulates from body fluids has enormous implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules used for this purpose result in inefficient ...
  • Xu, Chenjie; Sebastin, Monisha; Lee, Albert; Holwell, Nathan; Xu, Calvin; Mu, Luye; Miranda-Nieves, David; Lee, Yuhan; Langer, Robert S; Lin, Charles; Karp, Jeffrey (Wiley Blackwell, 2015-11)
    Delivery of tissue glues through small-bore needles or trocars is critical for sealing holes, affixing medical devices, or attaching tissues together during minimally invasive surgeries. Inspired by the granule-packaged ...
  • Ma, Mingming; Guo, Liang; Anderson, Daniel Griffith; Langer, Robert (American Association for the Advancement of Science (AAAS), 2013-01)
    Here we describe the development of a water-responsive polymer film. Combining both a rigid matrix (polypyrrole) and a dynamic network (polyol-borate), strong and flexible polymer films were developed that can exchange ...
  • Petrocchi, Marinella; Spognardi, Angelo; Santi, Paolo (Springer US, 2016-03)
    Fraglets represent an execution model for communication protocols that resembles the chemical reactions in living organisms. The strong connection between their way of transforming and reacting and formal rewriting systems ...
  • Chan, Wan Simon; Dedon, Peter C. (Hindawi Pub. Corp., 2010-10)
    DNA and other biomolecules are subjected to damaging chemical reactions during normal physiological processes and in states of pathophysiology caused by endogenous and exogenous mechanisms. In DNA, this damage affects ...
  • Penterman, Jon; Singh, Pradeep K.; Walker, Graham C. (American Society for Microbiology, 2014-07)
    LexA and two structurally related regulators, PrtR and PA0906, coordinate the Pseudomonas aeruginosa SOS response. RecA-mediated autocleavage of LexA induces the expression of a protective set of genes that increase DNA ...
  • Schulte, Joost; Littleton, J. Troy (Research Trends, 2011-01)
    Huntington’s Disease is an adult-onset dominant heritable disorder characterized by progressive psychiatric disruption, cognitive deficits, and loss of motor coordination. It is caused by expansion of a polyglutamine tract ...
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