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Browsing MIT Open Access Articles by Title

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  • Demaine, Erik D.; Demaine, Martin L.; Hart, Vi; Iacono, John; Langerman, Stefan; O’Rourke, Joseph (Springer-Verlag, 2011-05)
    We construct the first two continuous bloomings of all convex polyhedra. First, the source unfolding can be continuously bloomed. Second, any unfolding of a convex polyhedron can be refined (further cut, by a linear number ...
  • Ma, Minglin; Titievsky, Kirill; Thomas, Edwin L.; Rutledge, Gregory C. (American Chemical Society, 2009-03)
    Fibers with long-range ordered internal structures have applications in various areas such as photonic band gap fibers, optical waveguides, wearable power, sensors, and sustained drug release. Up to now, such fibers have ...
  • Hirose, Masashi; Aiello, Clarice Demarchi; Cappellaro, Paola (American Physical Society, 2012-12)
    Solid-state qubits hold the promise to achieve an unmatched combination of sensitivity and spatial resolution. To achieve their potential, the qubits need, however, to be shielded from the deleterious effects of the ...
  • Han, Jongyoon; Mao, Pan; Fu, Jianping (Nature Publishing Group, 2009-10)
    The anisotropic nanofluidic-filter (nanofilter) array (ANAANAANA) is a unique molecular-sieving structure for separating biomolecules. In this protocol we describe the fabrication of planar and vertical ANAANAANA chips and ...
  • Zhang, Yun; Jamison, Timothy F.; Patel, Sejal; Mainolfi, Nello (American Chemical Society (ACS), 2010-12)
    A convenient and efficient flow method for Ullmann condensations, Sonogashira couplings, and decarboxylation reactions using a commercially available copper tube flow reactor (CTFR) is described. The heated CTFR effects ...
  • Webb, Damien; Jamison, Timothy F. (Royal Society of Chemistry, The, 2010-09)
    Using continuous flow techniques for multi-step synthesis enables multiple reaction steps to be combined into a single continuous operation. In this mini-review we discuss the current state of the art in this field and ...
  • Leduc, Andrew B.; Jamison, Timothy F. (American Chemical Society (ACS), 2011-06)
    We report a method for the oxidation of a range of alcohols and aldehydes utilizing a simple flow system of alcohols in EtOAc with a stream of 12.5% NaOCl and catalytic Bu[subscript 4]NBr. Secondary alcohols are oxidized ...
  • Shen, Bo; Bedore, Matthew W.; Sniady, Adam; Jamison, Timothy F. (Royal Society of Chemistry, 2012-06)
    A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dide ...
  • Shen, Bo; Jamison, Timothy F. (CSIRO Publishing, 2013-11)
    A new photochemical flow reactor has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly improved both ...
  • Guzman de Villoria, R.; Steiner III, Stephen Alan; Hart, A. J.; Wardle, Brian L. (Institute of Materials, Minerals and Mining, 2011-08)
    Vertically aligned carbon nanotubes (VACNTs), sometimes called forests or carpets, are a promising material due to their unique physical and scale-dependent physical properties [1-3]. Continuous production of VACNTs is ...
  • Guzman de Villoria, Roberto; Wardle, Brian L. (Nano Science and Technology Institute/CRC Press, 2011-06)
    Vertically aligned carbon nanotubes are one of the most promising materials due their numerous applications in flexible electronic devices, biosensors and multifunctional aircraft materials, among others. However, the ...
  • Webb, Damien; Jamison, Timothy F. (American Chemical Society (ACS), 2012-04)
    A continuous protocol for the two-carbon homologation of esters to α,β-unsaturated esters is described. This multireactor homologation telescopes an ester reduction, phosphonate deprotonation, and Horner–Wadsworth–Emmons ...
  • Daskalakis, Constantinos; Papadimitriou, Christos (Society for Industrial and Applied Mathematics, 2011-01)
    We introduce CLS, for continuous local search, a class of polynomial-time checkable total functions that lies at the intersection of PPAD and PLS, and captures a particularly benign kind of local optimization in which the ...
  • Mooney, Luke M.; Herr, Hugh M. (Institute of Electrical and Electronics Engineers, 2013-06)
    Actuator efficiency is an important factor in the design of powered leg prostheses, orthoses, exoskeletons, and legged robots. A continuously-variable series-elastic actuator (CV-SEA) is presented as an efficient actuator ...
  • Poh, Ming-Zher; Loddenkemper, Tobias; Swenson, Nicholas C.; Goyal, Shubhi; Madsen, Joseph R.; Picard, Rosalind W. (Institute of Electrical and Electronics Engineers, 2010-08)
    We present a novel method for monitoring sympathetic nervous system activity during epileptic seizures using a wearable sensor measuring electrodermal activity (EDA). The wearable sensor enables long-term, continuous EDA ...
  • Cunningham, Daniel P.; Asada, Harry (Institute of Electrical and Electronics Engineers, 2010-07)
    A simple, under-actuated robotic winch, called the “Winch-Bot,” is developed for surface inspection of a large object. The Winch-Bot, placed over an object surface, has only one actuator for tracing a free geometric path ...
  • Alvarez, Alejandro J.; Myerson, Allan S. (American Chemical Society, 2010-03)
    Crystallization processes in the pharmaceutical industry are usually designed to obtain crystals with controlled size, shape, purity, and polymorphic form. Knowledge of the process conditions required to fabricate crystals ...
  • Heldt, Thomas; Kashif, Faisal Mahmood; Verghese, George C.; Sulemanji, Mustafa; O’Leary, Heather M.; Plessis, Adré J. du (Springer-Verlag, 2012-02)
    Oxidative stress during fetal development, delivery, or early postnatal life is a major cause of neuropathology, as both hypoxic and hyperoxic insults can significantly damage the developing brain. Despite the obvious need ...
  • Malviya, Nirmesh; Madden, Samuel R.; Bhattacharya, Arnab (International Conference on Data Engineering, 2011-04)
    In this paper, we address the problem of answering continuous route planning queries over a road network, in the presence of updates to the delay (cost) estimates of links. A simple approach to this problem would be to ...
  • Cheow, Lih Feng; Han, Jongyoon (American Chemical Society, 2011-09)
    We describe an electrokinetic concentration-enhanced aptamer affinity probe electrophoresis assay to achieve highly sensitive and quantitative detection of protein targets in a microfluidic device. The key weaknesses of ...
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