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Browsing MIT Open Access Articles by Title

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  • Neve, Rachael L.; Zhou, Yu; Won, Jaejoon; Karlsson, Mikael Guzman; Zhou, Miou; Rogerson, Thomas; J., Balaji; Poirazi, Panayiota; Silva, Alcino J. (Nature Publishing Group, 2009-09)
    The mechanisms that determine how information is allocated to specific regions and cells in the brain are fundamentally important for memory capacity, storage and retrieval, but are poorly understood. Here, we manipulated ...
  • Angrist, Joshua; Pischke, Jorn-Steffen (American Economic Association, 2010)
    Just over a quarter century ago, Edward Leamer (1983) reflected on the state of empirical work in economics. He urged empirical researchers to “take the con out of econometrics” and memorably observed (p. 37): “Hardly ...
  • Benmelech, Efraim; Bergman, Nittai (American Economic Association, 2012-10)
    This paper studies the limitations of monetary policy in stimulating credit and investment. We show that, under certain circumstances, unconventional monetary policies fail in that liquidity injections into the banking ...
  • Blanchard, Olivier Jean (Ifo Institute for Economic Research, 2009-01)
    The purpose of this lecture is to look beyond the complex events that characterize the global financial and economic crisis, identify the basic mechanisms, and infer the policies needed to resolve the current crisis, as ...
  • Yaung, Stephanie J.; Esvelt, Kevin M.; Church, George M. (Public Library of Science, 2014-06)
    Bacteria rely on two known DNA-level defenses against their bacteriophage predators: restriction-modification and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-associated (Cas) systems. Certain ...
  • Zhu, Lihua J.; Holmes, Benjamin R.; Aronin, Neil; Brodsky, Michael H. (Public Library of Science, 2014-09)
    CRISPR-Cas systems are a diverse family of RNA-protein complexes in bacteria that target foreign DNA sequences for cleavage. Derivatives of these complexes have been engineered to cleave specific target sequences depending ...
  • Oehmen, Josef; Steuber, Marc (Design Society, 2012-05)
    The success framework describes performance aspects of large-scale engineering programs. It consists of 26 metrics in 5 categories. They are: 1. Enterprise strategy alignment, 2. Performance and quality, 3. Learning and ...
  • Fardin, M. A.; Ober, Thomas Joseph; Gay, C.; Gregoire, G.; McKinley, Gareth H.; Lerouge, S. (Institute of Physics Publishing, 2011-11)
    In the past twenty years, shear-banding flows have been probed by various techniques, such as rheometry, velocimetry and flow birefringence. In micellar solutions, many of the data collected exhibit unexplained spatio-temporal ...
  • Heilmann, Ralf K.; Davis, John E.; Dewey, Dan; Bautz, Mark W.; Foster, Richard F.; Bruccoleri, Alexander Robert; Mukherjee, Pran; Robinson, David; Huenemoerder, David P.; Marshall, Herman Lee; Schattenburg, Mark Lee; Schulz, Norbert S.; Guo, L. Jay; Kaplan, Alex F.; Schweikart, Russell B. (Institute of Electrical and Electronics Engineers, 2010-06)
    High-resolution spectroscopy at energies below 1 keV covers the lines of C, N, O, Ne and Fe ions, and is central to studies of the Interstellar Medium, the Warm Hot Intergalactic Medium, warm absorption and outflows in ...
  • Berggren, Karl K.; Hortensius, H. L.; Driessen, E. F. C.; Klapwijk, T. M.; Clem, J. R. (American Institute of Physics (AIP), 2012-05)
    We demonstrate experimentally that the critical current in superconducting NbTiN wires is dependent on their geometrical shape, due to current-crowding effects. Geometric patterns such as 90˚ corners and sudden expansions ...
  • Crandall, W.; Kemerer, Chris F.; MacCormack, Alan D.; Cusumano, Michael A. (Institute of Electrical and Electronics Engineers, 2009-08)
    This article focuses on how to choose the "right" software development process, how to structure global software design chains, how to manage the interaction of project structure and software design, and how to balance ...
  • Movassagh, Ramis; Shor, Peter W.; Caha, Libor; Bravyi, Sergey; Nagaj, Daniel (American Physical Society, 2012-11)
    Frustration-free (FF) spin chains have a property that their ground state minimizes all individual terms in the chain Hamiltonian. We ask how entangled the ground state of a FF quantum spin-s chain with nearest-neighbor ...
  • Berker, A. Nihat; Hinczewski, Michael; Netz, Roland R. (American Physical Society, 2009-10)
    Percolation in a scale-free hierarchical network is solved exactly by renormalization-group theory in terms of the different probabilities of short-range and long-range bonds. A phase of critical percolation, with algebraic ...
  • Kelsch, Wolfgang; Lin, Chia-Wei; Mosley, Colleen P.; Lois, Carlos (Society for Neuroscience, 2009-09)
    New neurons integrate in large numbers into the mature olfactory bulb circuit throughout life. The factors controlling the synaptic development of adult-born neurons and their connectivity remain essentially unknown. We ...
  • Malik, Rahul; Abdellahi, Aziz; Ceder, Gerbrand (Electrochemical Society, 2013-05)
    With the ever-growing public and now commercial sentiment supporting the widespread adoption of low and zero-emission vehicles, it is unsurprising that Li-ion batteries which currently assume the bulk of the cost of ...
  • Machado, Daniel; Costa, Rafael S.; Rocha, Miguel; Rocha, Isabel; Tidor, Bruce; Ferreira, Eugenio C. (Springer Berlin / Heidelberg, 2009-06)
    Integration of different kinds of biological processes is an ultimate goal for whole-cell modelling. We briefly review modelling formalisms that have been used in Systems Biology and identify the criteria that must be ...
  • El-Haibi, Christelle P.; Bell, George W.; Zhang, Jiangwen; Collmann, Anthony Y.; Wood, David; Scherber, Cally M.; Csizmadia, Eva; Mariani, Odette; Zhu, Cuihua; Campagne, Antoine; Toner, Mehmet; Bhatia, Sangeeta N.; Irimia, Daniel; Vincent-Salomon, Anne; Karnoub, Antoine E. (National Academy of Sciences (U.S.), 2012-10)
    Mesenchymal stem cells (MSCs) are multipotent progenitor cells with the ability to differentiate into multiple mesoderm lineages in the course of normal tissue homeostasis or during injury. We have previously shown that ...
  • Jones, S. R.; Deisseroth, K.; Carlen, M.; Meletis, Konstantinos; Siegle, Joshua Handman; Cardin, Jessica A.; Futai, Kensuke; Vierling-Claassen, Dorea L.; Ruhlmann, C.; Sheng, Morgan Hwa-Tze; Moore, Christopher I.; Tsai, Li-Huei (Nature Publishing Group, 2011-04)
    Synchronous recruitment of fast-spiking (FS) parvalbumin (PV) interneurons generates gamma oscillations, rhythms that emerge during performance of cognitive tasks. Administration of N-methyl-D-aspartate (NMDA) receptor ...
  • Lebrand, Cecile; Lanier, Lorene M; Krause, Matthias; Svitkina, Tatyana M; Borisy, Gary G; Dent, Erik W.; Strasser, Geraldine A.; Gertler, Frank (Elsevier, 2004-04)
    Ena/VASP proteins play important roles in axon outgrowth and guidance. Ena/VASP activity regulates the assembly and geometry of actin networks within fibroblast lamellipodia. In growth cones, Ena/VASP proteins are concentrated ...
  • Demirtas, Sefa; del Alamo, Jesus A. (Institute of Electrical and Electronics Engineers, 2009-11)
    We have evaluated the electrical reliability of GaN HEMTs on Si by carrying out V[subscript DS] = 0 V step-stress experiments. We have found that these devices show a degradation pattern that is very similar to that of ...
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