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Browsing MIT Open Access Articles by Title

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  • Hou, Jennifer Y.; Grant, Robert A.; Sauer, Robert T.; Roman-Hernandez, Giselle; Baker, Tania; Sauer, Robert T. (Elsevier, 2011-07)
    The ClpS adaptor delivers N-end rule substrates to ClpAP, an energy-dependent AAA+ protease, for degradation. How ClpS binds specific N-end residues is known in atomic detail and clarified here, but the delivery mechanism ...
  • Sauer, Robert T.; Baker, Tania (Elsevier, 2011-06)
    ClpXP is a AAA+ protease that uses the energy of ATP binding and hydrolysis to perform mechanical work during targeted protein degradation within cells. ClpXP consists of hexamers of a AAA+ ATPase (ClpX) and a tetradecameric ...
  • Borodin, Alexei (Independent University of Moscow, 2014-03)
    We prove a CLT for spectra of submatrices of real symmetric and Hermitian Wigner matrices. We show that if in the standard normalization the fourth moment of the off-diagonal entries is GOE/GUE-like then the limiting ...
  • Bufetov, Alexey; Borodin, Alexei (Springer-Verlag, 2013-04)
    We study the asymptotics of traces of (noncommutative) monomials formed by the images of certain elements of the universal enveloping algebra of the infinite-dimensional unitary group in its Plancherel representations. We ...
  • Pham, Hubert; Paluska, Justin Mazzola; Miller, Robert C.; Ward, Stephen A. (Association for Computing Machinery (ACM), 2012-10)
    On the desktop, users are accustomed to having visible handles to objects that they want to organize, share, or manipulate. Web applications today feature many classes of such objects, like flight itineraries, products ...
  • Daloz, Anne S.; Camargo, S. J.; Kossin, James P.; Horn, M.; Jonas, J. A.; Kim, D.; LaRow, T.; Lim, Y.-K.; Patricola, C. M.; Roberts, M.; Scoccimarro, E.; Shaevitz, D.; Vidale, P. L.; Wang, H.; Wehner, M.; Zhao, M.; Emanuel, Kerry Andrew (American Meteorological Society, 2015-02)
    A realistic representation of the North Atlantic tropical cyclone tracks is crucial as it allows, for example, explaining potential changes in U.S. landfalling systems. Here, the authors present a tentative study that ...
  • Martini, Paul; Miller, Eric D.; Brodwin, M.; Stanford, S. A.; Gonzalez, Anthony H.; Bautz, Marshall W.; Hickox, R. C.; Stern, D.; Eisenhardt, P. R.; Galametz, A.; Norman, D.; Jannuzi, Buell T.; Dey, A.; Murray, S.; Jones, C.; Brown, M. J. I. (Institute of Physics/American Astronomical Society, 2013-05)
    The fraction of cluster galaxies that host luminous active galactic nuclei (AGNs) is an important probe of AGN fueling processes, the cold interstellar medium at the centers of galaxies, and how tightly black holes and ...
  • Chen, Jerry L.; Villa, Katherine Leigh; Cha, Jae Won; So, Peter T. C.; Kubota, Yoshiyuki; Nedivi, Elly (Elsevier B.V., 2012-04)
    A key feature of the mammalian brain is its capacity to adapt in response to experience, in part by remodeling of synaptic connections between neurons. Excitatory synapse rearrangements have been monitored in vivo by ...
  • Chan, Maria K.; Reed, J.; Donadio, D.; Mueller, Timothy K.; Meng, Ying Shirley; Galli, G.; Ceder, Gerbrand (American Physical Society, 2010-05)
    We investigate the parametrization and optimization of thermal conductivity in silicon-germanium alloy nanowires by the cluster-expansion technique. Si1−xGex nanowires are of interest for thermoelectric applications and ...
  • Syed, Zeeshan; Guttag, John V.; Stultz, Collin M. (Springer, 2007-03)
    This paper describes novel fully automated techniques for analyzing large amounts of cardiovascular data. In contrast to traditional medical expert systems our techniques incorporate no a priori knowledge about disease ...
  • Jiang, Shan; Ferreira, Joseph, Jr.; Gonzalez, Marta C. (Springer-Verlag, 2012-04)
    Data mining and statistical learning techniques are powerful analysis tools yet to be incorporated in the domain of urban studies and transportation research. In this work, we analyze an activity-based travel survey conducted ...
  • Egedal-Pedersen, Jan; Le, A.; Katz, Noam Karasov; Chen, L.-J.; Lefebvre, B.; Daughton, W.; Fazakerley, A. (American Geophysical Union (AGU), 2010-03)
    [1] So-called bidirectional electron beams have been observed by a number of spacecraft missions mainly in the inflow of reconnection regions. Here we show that these beam-like features in the electron distribution function ...
  • Xue, Wen; Kitzing, Thomas; Roessler, Stephanie; Zuber, Johannes; Krasnitz, Alexander; Schultz, Nikolaus; Revill, Kate; Weissmueller, Susann; Rappaport, Amy R.; Simon, Janelle; Zhang, Jack; Luo, Weijun; Hicks, James; Zender, Lars; Wang, Xin Wei; Powers, Scott; Wigler, Michael; Lowe, Scott W. (National Academy of Sciences (U.S.), 2012-05)
    The large chromosomal deletions frequently observed in cancer genomes are often thought to arise as a “two-hit” mechanism in the process of tumor-suppressor gene (TSG) inactivation. Using a murine model system of hepatocellular ...
  • Wechsung, Achim; Schaber, Spencer D.; Barton, Paul I. (Springer US, 2013-03)
    In continuous branch-and-bound algorithms, a very large number of boxes near global minima may be visited prior to termination. This so-called cluster problem (J Glob Optim 5(3):253–265, 1994) is revisited and a new analysis ...
  • Delgado, Mercedes; Porter, Michael E.; Stern, Scott (Oxford University Press, 2010-05)
    This article examines the role of regional clusters in regional entrepreneurship. We focus on the distinct influences of convergence and agglomeration on growth in the number of start-up firms as well as in employment in ...
  • Rouse, Elliott Jay; Mooney, Luke M.; Martinez-Villalpando, Ernesto C.; Herr, Hugh M. (2013-06)
    The cyclic and often linear torque-angle relationship of locomotion presents the opportunity to innovate on the design of traditional series-elastic actuators (SEAs). In this paper, a novel modification to the SEA ...
  • Mak, Terrence; Lum, Kai-Pui; Ng, H. S.; Rachmuth, Guy; Poon, Chi-Sang (Institute of Electrical and Electronics Engineers, 2010-07)
    Dynamic programming (DP) is a fundamental algorithm for complex optimization and decision-making in many engineering and biomedical systems. However, conventional DP computation based on digital implementation of the ...
  • Yamashita, Hirofumi; Sodini, Charles G. (Institute of Electrical and Electronics Engineers (IEEE), 2009-10)
    An imager with an integrated fully programmable bit-serial column-parallel processor is proposed to meet the demand for a compact and versatile system-on-imager chip for consumer applications. The on-imager processor is ...
  • Stojanovic, Vladimir Marko; Joshi, Ajay J.; Batten, Christopher; Kwon, Yong-Jin; Beamer, Scott; Chen, Sun; Asanovic, Krste (Institute of Electrical and Electronics Engineers, 2010-02)
    This paper presents a monolithically integrated dense WDM photonic network for manycore processors, optimized for loss and power footprint of optical components, which can achieve up to 10x better energy-efficiency and ...
  • Gomez-Ceballos, Guillelmo; Klute, Markus; Levin, Andrew Michael; Paus, Christoph M. E.; Ralph, Duncan Kelley; Yang, Mingming (IOP Publishing, 2014-06)
    During the first run, CMS collected and processed more than 10B data events and simulated more than 15B events. Up to 100k processor cores were used simultaneously and 100PB of storage was managed. Each month petabytes of ...
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