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Browsing MIT Open Access Articles by Title

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  • Bhubalan, Kesaven; Chuah, Jo-Ann; Shozui, Fumi; Taguchi, Seiichi; Sudesh, Kumar; Brigham, Christopher J.; Sinskey, Anthony J.; Rha, ChoKyun (American Society for Microbiology, 2011-03)
    The synthesis of bacterial polyhydroxyalkanoates (PHA) is very much dependent on the expression and activity of a key enzyme, PHA synthase (PhaC). Many efforts are being pursued to enhance the activity and broaden the ...
  • Lau, Denvid; Buyukozturk, Oral; Buehler, Markus J. (Cambridge University Press (Materials Research Society), 2012-04)
    Organic–inorganic interfaces exist in many natural or synthetic materials, such as mineral–protein interfaces found in bone and epoxy–silica interfaces found in concrete construction. Here, we report a model to predict the ...
  • Narita, Norio; Hirano, Teruyuki; Fukui, Akihiko; Hori, Yasunori; Sanchis-Ojeda, Roberto; Ryu, Tsuguru; Kusakabe, Nobuhiko; Kudo, Tomoyuki; Onitsuka, Masahiro; Delrez, Laetitia; Gillon, Michael; Jehin, Emmanuel; McCormac, James; Holman, Matthew; Izumiura, Hideyuki; Takeda, Yoichi; Tamura, Motohide; Yanagisawa, Kenshi; Winn, Joshua Nathan (IOP Publishing, 2015-12)
    K2-19 (EPIC201505350) is an interesting planetary system in which two transiting planets with radii ~7 R[subscript ⊕] (inner planet b) and ~4 R[subscript ⊕] (outer planet c) have orbits that are nearly in a 3:2 mean-motion ...
  • Talpe, Matthieu J.; Yang, Di; Neumann, Gregory A.; Solomon, Sean C.; Vilas, Faith; Zuber, Maria; Mazarico, Erwan Matias (American Geophysical Union (AGU), 2012-12)
    Earth-based radar images of Mercury show radar-bright material inside impact craters near the planet's poles. A previous study indicated that the polar-deposit-hosting craters (PDCs) at Mercury's north pole are shallower ...
  • Boche, Holger; Monich, Ullrich (Pleiades Publishing, 2013-10)
    The peak value of a signal is a characteristic that has to be controlled in many applications. In this paper we analyze the peak value of the Hilbert transform for the space B[∞ over π] of bounded bandlimited signals. It ...
  • Torres, Pedro J.; Fletcher, Erin M.; Gibbons, Sean M.; Bouvet, Michael; Doran, Kelly S.; Kelley, Scott T.; Gibbons, Sean (PeerJ Inc., 2015-11)
    Clinical manifestations of pancreatic cancer often do not occur until the cancer has undergone metastasis, resulting in a very low survival rate. In this study, we investigated whether salivary bacterial profiles might ...
  • Bautz, Marshall W.; Busacker, David E.; Prigozhin, Gregory; Suntharalingam, Vyshnavi; Foster, Richard F.; Kissel, Steve E.; La Marr, Beverly J.; Soares, Antonio M.; Villasenor, Joel (IEEE transactions on electron devicesInstitute of Electrical and Electronics Engineers, 2009-11)
    We have developed a back-illuminated active pixel sensor (APS) which includes an SOI readout circuit and a silicon diode detector array implemented in a separate high-resistivity wafer. Both are connected together using a ...
  • Sabatini, David M.; Liu, Qingsong; Xu, Chunxiao; Kirubakaran, Sivapriya; Zhang, Xin; Hur, Wooyoung; Liu, Yan; Kwiatkowski, Nicholas P.; Wang, Jinhua; Westover, Kenneth D.; Gao, Peng; Ercan, Dalia; Niepel, Mario; Thoreen, Carson C.; Kang, Seong A.; Patricelli, Matthew P.; Wang, Yuchuan; Tupper, Tanya; Altabef, Abigail; Kawamura, Hidemasa; Held, Kathryn D.; Chou, Danny M.; Elledge, Stephen J.; Janne, Pasi A.; Wong, Kwok-Kin; Gray, Nathanael S. (American Association for Cancer Research, 2013-02)
    mTOR is a highly conserved serine/threonine protein kinase that serves as a central regulator of cell growth, survival, and autophagy. Deregulation of the PI3K/Akt/mTOR signaling pathway occurs commonly in cancer and ...
  • Macdonald, Mara L.; Rodriguez, Natalia M.; Shah, Nisarg J.; Hammond, Paula T. (American Chemical Society, 2010-07)
    Fibroblast growth factor 2 (FGF-2) is a potent mediator of stem cell differentiation and proliferation. Although FGF-2 has a well-established role in promoting bone tissue formation, flaws in its delivery have limited its ...
  • Rigby, M.; Zammit-Mangion, A.; Manning, Alistair J.; Fraser, P. J.; Harth, C. M.; Kim, K.-R.; Krummel, P. B.; Li, S.; O'Doherty, Simon; Park, S.; Salameh, P. K.; Steele, L. P.; Weiss, R. F.; Ganesan, Anita Lakshmi; Prinn, Ronald G.; Muhle, Jens (Copernicus GmbH, 2014-04)
    We present a hierarchical Bayesian method for atmospheric trace gas inversions. This method is used to estimate emissions of trace gases as well as "hyper-parameters" that characterize the probability density functions ...
  • Gunturu, Udaya Bhaskar; Schlosser, C. A. (Copernicus GmbH, 2012-10)
    Wind resource in the continental and offshore United States has been reconstructed and characterized using metrics that describe, apart from abundance, its availability, persistence and intermittency. The Modern Era ...
  • Miller Singley, Alison T.; Wendelken, Carter; Bunge, Silvia A.; Mackey, Allyson (Public Library of Science, 2015-09)
    We have reported previously that intensive preparation for a standardized test that taxes reasoning leads to changes in structural and functional connectivity within the frontoparietal network. Here, we investigated whether ...
  • Byun, Sangwon; Hecht, Vivian Chaya; Manalis, Scott R (Elsevier, 2015-10)
    Cellular physical properties are important indicators of specific cell states. Although changes in individual biophysical parameters, such as cell size, density, and deformability, during cellular processes have been ...
  • Byun, Sangwon; Son, Sungmin; Amodei, Dario; Cermak, Nathan; Shaw, Josephine; Kang, Joon Ho; Hecht, Vivian Chaya; Winslow, Monte M.; Jacks, Tyler E.; Mallick, Parag; Manalis, Scott R. (National Academy of Sciences (U.S.), 2013-04)
    Metastasis requires the penetration of cancer cells through tight spaces, which is mediated by the physical properties of the cells as well as their interactions with the confined environment. Various microfluidic approaches ...
  • Holmes, David W.; Williams, John R.; Tilke, Peter G. (American Institute of Physics, 2010-05)
    In this paper, a 3D Smooth Particle Hydrodynamics (SPH) simulator for modeling grain scale fluid flow in porous rock is presented. The versatility of the SPH method has driven its use in increasingly complex areas of flow ...
  • Baratchart, L; Hardin, D P; Andrade Lima, Eduardo; Saff, E. B.; Weiss, Benjamin P. (Institute of Physics Publishing, 2013-01)
    Recently developed scanning magnetic microscopes measure the magnetic field in a plane above a thin-plate magnetization distribution. These instruments have broad applications in geoscience and materials science, but are ...
  • Bowens-Rubin, Rachel (IOP Publishing, 2012-05)
    We present the analysis of the light curves of nine high-magnification single-lens gravitational microlensing events with lenses passing over source stars, including OGLE-2004-BLG-254, MOA-2007-BLG-176, MOA-2007-BLG-233/ ...
  • Trusheim, Mark; Aitken, Murray L.; Berndt, Ernst R. (National Bureau of Economic Research, 2010-01)
    While much has been written about the distinctions between biologics and small molecules in terms of their scientific, manufacturing and regulatory experiences, relatively little has been published comparing their clinical ...
  • Chen, Zhe; Brown, Emery N.; Barbieri, Riccardo (Institute of Electrical and Electronics Engineers, 2010-06)
    Human heartbeat intervals are known to have nonlinear and nonstationary dynamics. In this paper, we propose a model of R-R interval dynamics based on a nonlinear Volterra-Wiener expansion within a point process framework. ...
  • Muirhead, Philip S.; Johnson, John Asher; Apps, Kevin; Carter, Joshua Adam; Morton, Timothy D.; Fabrycky, Daniel C.; Pineda, John Sebastian; Bottom, Michael; Schlawin, Everett; Hamren, Katherine; Covey, Kevin R.; Crepp, Justin R.; Pepper, Joshua; Hebb, Leslie; Kirby, Evan N.; Howard, Andrew W.; Isaacson, Howard; Marcy, Geoffrey W.; Levitan, David; Diaz-Santos, Tanio; Armus, Lee; Lloyd, James P.; Stassun, Keivan; Rojas-Ayala, Barbara (IOP Publishing, 2012-02)
    We characterize the star KOI 961, an M dwarf with transit signals indicative of three short-period exoplanets discovered by the Kepler mission. We proceed by comparing KOI 961 to Barnard's Star, a nearby, well-characterized ...
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