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Browsing MIT Open Access Articles by Title

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  • Khadilkar, Harshad Dilip; Balakrishnan, Hamsa (American Institute of Aeronautics and Astronautics, 2012-08)
    This paper describes a dynamic programming formulation of the airport surface traffic management problem. Movement of aircraft is modeled as the flow of traffic on a network, with stochastic link travel times. This is ...
  • Geyer, Hartmut; Eilenberg, Michael Frederick; Herr, Hugh M. (Institute of Electrical and Electronics Engineers (IEEE), 2010-04)
    Control schemes for powered ankle-foot prostheses rely upon fixed torque-ankle state relationships obtained from measurements of intact humans walking at target speeds and across known terrains. Although effective at their ...
  • Iwase, Eiji; Hui, Pui-Chuen; Woolf, David; Rodriguez, Alejandro W; Johnson, Steven G.; Capasso, Federico; Lončar, Marko; Rodriguez, Alejandro W.; Johnson, Steven G. (IOP Publishing, 2012-06)
    In this paper we describe a general method to avoid stress-induced buckling of thin and large freestanding membranes. We show that using properly designed supports, in the form of microbeams, we can reduce the out-of-plane ...
  • Torborg, Christine L.; Nakashiba, Toshiaki; Tonegawa, Susumu; McBain, Chris J. (Society for Neuroscience, 2010-11)
    In somatosensory cortex, the relative balance of excitation and inhibition determines how effectively feedforward inhibition enforces the temporal fidelity of action potentials. Within the CA3 region of the hippocampus, ...
  • Lin, Daniel Chi-Hong; Quisel, John D.; Grossman, Alan D. (Elsevier, 1999-11)
    In B. subtilis, the chromosome partitioning proteins Soj (ParA) and Spo0J (ParB) regulate the initiation of sporulation. Soj is a negative regulator of sporulation gene expression, and Spo0J antagonizes Soj function. Using ...
  • Rubio-Texeira, Marta; Varnum, James M; Bieganowski, Pawel; Brenner, Charles (BioMed Central Ltd, 2002-05)
    Background: The FHIT gene is lost early in the development of many tumors. Fhit possesses intrinsic ApppA hydrolase activity though ApppA cleavage is not required for tumor suppression. Because a mutant form of Fhit that ...
  • Verma, Rajeev; Del Vecchi, Domitilla (Institute of Electrical and Electronics Engineers, 2011-10)
    We consider the problem of safety control in Hidden Mode Hybrid Systems (HMHS) that arises in the development of a semi-autonomous cooperative active safety system for collision avoidance at an intersection. We utilize the ...
  • Verma, Rajeev; Del Vecchio, Domitilla (Institute of Electrical and Electronics Engineers (IEEE), 2010-12)
    In this paper, we consider the safety control problem for hybrid systems with hidden modes. In particular, we propose an approach to translate the control problem with imperfect mode information into an equivalent problem ...
  • Wilson, J. R.; Parker, Ronald R.; Bonoli, Paul T.; Hubbard, Amanda E.; Hughes, Jerry W.; Ince-Cushman, Alexander; Kessel, C.; Ko, J. S.; Meneghini, Orso-Maria Corneli; Porkolab, Miklos; Reinke, Matthew Logan; Rice, John E.; Schmidt, Andrea Elizabeth; Shiraiwa, Shunichi; Scott, S.; Wallace, Gregory Marriner; Wright, John C. (American Institute of Physics, 2009-11)
    LHCD on Alcator C-Mod is being used in plasmas with parameters similar to those expected on ITER for the purpose of tailoring the plasma current profile. LHCD experiments have also produced intriguing results related to ...
  • Wongpiromsarn, Tichakorn; Frazzoli, Emilio (Institute of Electrical and Electronics Engineers (IEEE), 2012-12)
    We consider the synthesis of control policies for probabilistic systems, modeled by Markov decision processes, operating in partially known environments with temporal logic specifications. The environment is modeled by a ...
  • Yuan, Haidong (Institute of Electrical and Electronics Engineers, 2010-01)
    In this article we study the control of single spin in Markovian environment. Given an initial state, we compute all the possible states to which the spin can be driven at arbitrary time, under the assumption that fast ...
  • Lee, Seung Jae; McCormick, Michael S.; Lippard, Stephen J.; Cho, Uhn-Soo (Nature Publishing Group, 2013-02)
    Methanotrophs consume methane as their major carbon source and have an essential role in the global carbon cycle by limiting escape of this greenhouse gas to the atmosphere. These bacteria oxidize methane to methanol by ...
  • Lee, Mary E.; Baker, Tania; Sauer, Robert T. (Elsevier, 2010-04)
    ClpP is a self-compartmentalized protease, which has very limited degradation activity unless it associates with ClpX to form ClpXP or with ClpA to form ClpAP. Here, we show that ClpX binding stimulates ClpP cleavage of ...
  • Young, Richard A.; Young, Richard A. (Elsevier B.V., 2011-03)
    Embryonic stem cells and induced pluripotent stem cells hold great promise for regenerative medicine. These cells can be propagated in culture in an undifferentiated state but can be induced to differentiate into specialized ...
  • Maldonado, Roberto A.; Soriano, Michelle A.; Perdomo, L. Carolina; Sigrist, Kirsten; Irvine, Darrell J.; Decker, Thomas; Glimcher, Laurie H. (Rockefeller University Press, 2009)
    The antigen recognition interface formed by T helper precursors (Thps) and antigen-presenting cells (APCs), called the immunological synapse (IS), includes receptors and signaling molecules necessary for Thp activation and ...
  • Attner, Michelle Andrea; Amon, Angelika B. (American Society for Cell Biology, 2012-06)
    The mitotic exit network (MEN) is an essential GTPase signaling pathway that triggers exit from mitosis in budding yeast. We show here that during meiosis, the MEN is dispensable for exit from meiosis I but contributes to ...
  • Merrikh, Houra (John Wiley & Sons, Inc., 2011-09)
    Proper coordination of DNA replication with cell growth and division is critical for production of viable progeny. In bacteria, coordination of DNA replication with cell growth is generally achieved by controlling activity ...
  • Wu, Chia-Yung; Rolfe, Philip Alexander; Gifford, David K.; Fink, Gerald R. (Public Library of Science, 2010-11)
    Cell size increases significantly with increasing ploidy. Differences in cell size and ploidy are associated with alterations in gene expression, although no direct connection has been made between cell size and transcription. ...
  • Landsman, Alexandra S.; Slotine, Jean-Jacques E. (American Physical Society, 2012-10)
    Understanding synchronous and traveling-wave oscillations, particularly as they relate to transitions between different types of behavior, is a central problem in modeling biological systems. Here, we address this problem ...
  • Andalman, Aaron S.; Foerster, Jakob N.; Fee, Michale S. (Public Library of Science, 2011-09)
    Learned motor behaviors require descending forebrain control to be coordinated with midbrain and brainstem motor systems. In songbirds, such as the zebra finch, regular breathing is controlled by brainstem centers, but ...
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