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Browsing MIT Open Access Articles by Title

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  • Ma, Dengke; Zheng, Shu; Bhatla, Nikhil; Pender, Corinne Lenore; Horvitz, H. Robert; Rothe, Michael; Menzel, Ralph (American Association for the Advancement of Science (AAAS), 2013-06)
    Oxygen deprivation followed by reoxygenation causes pathological responses in many disorders, including ischemic stroke, heart attacks, and reperfusion injury. Key aspects of ischemia-reperfusion can be modeled by a ...
  • Hendriks, Bart S.; Cosgrove, Benjamin D.; Alexopoulos, Leonidas G.; Hang, Ta-Chun; Sorger, Peter K.; Griffith, Linda G.; Lauffenburger, Douglas A. (Royal Society of Chemistry, 2010-04)
    Idiosyncratic drug hepatotoxicity is a major problem in pharmaceutical development due to poor prediction capability of standard preclinical toxicity assessments and limited knowledge of its underlying mechanisms. Findings ...
  • Chang, Fred; Bathe, Mark (Elsevier B.V., 2010-01)
    Cytokinesis, the final stage of the cell division cycle, requires the proper placement, assembly and contraction of an actomyosin-based contractile ring. Conserved sets of cytokinesis proteins and pathways have now been ...
  • Janes, Peter W.; Wimmer-Kleikamp, Sabine H.; Frangakis, Achilleas S.; Treble, Kane; Griensshaber, Bettina; Sabet, Ola; Grabenbauer, Markus; Ting, Alice Y.; Saftig, Paul; Bastiaens, Philippe I.; Lackmann, Martin (Public Library of Science, 2009-10)
    Release of cell surface-bound ligands by A-Disintegrin-And-Metalloprotease (ADAM) transmembrane metalloproteases is essential for signalling by cytokine, cell adhesion, and tyrosine kinase receptors. For Eph receptor ...
  • Dent, Erik W.; Gertler, Frank (Elsevier, 2003-10)
    Recent studies indicate the actin and microtubule cytoskeletons are a final common target of many signaling cascades that influence the developing neuron. Regulation of polymer dynamics and transport are crucial for the ...
  • Dewey, C. Forbes; Ayyadurai, VA Shiva (Springer-Verlag, 2010-10)
    A grand challenge of computational systems biology is to create a molecular pathway model of the whole cell. Current approaches involve merging smaller molecular pathway models’ source codes to create a large monolithic ...
  • Darby, Alison; Lertpiriyapong, Kvin; Sarkar, Ujjal; Seneviratne, Uthpala I.; Park, Danny S.; Gamazon, Eric R.; Batchelder, Chara; Cheung, Cheryl; Buckley, Ellen Marie; Taylor, Nancy S.; Shen, Zeli; Tannenbaum, Steven Robert; Wishnok, John S.; Fox, James G. (Public Library of Science, 2014-07)
    Klebsiella oxytoca is an opportunistic pathogen implicated in various clinical diseases in animals and humans. Studies suggest that in humans K. oxytoca exerts its pathogenicity in part through a cytotoxin. However, cytotoxin ...
  • Zhao, M.; Yamamoto, R. K.; Taylor, Frank E.; Spitznagel, M.; Sciolla, Gabriella; Henderson, Shawn Wesley; Dujmic, Denis; Cowan, Ray Franklin; Fisher, Peter H. (American Physical Society, 2009-06)
    We report on a Dalitz plot analysis of B-→D+π-π- decays, based on a sample of about 383×106 Υ(4S)→BB̅ decays collected with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. We find the total branching ...
  • Zhao, M.; Yamamoto, R. K.; Spitznagel, M.; Sciolla, Gabriella; Henderson, Shawn Wesley; Dujmic, Denis; Cowan, Ray Franklin; Fisher, Peter H. (American Physical Society, 2009-04)
    We present a Dalitz plot analysis of charmless B[superscript ±] decays to the final state pi[superscript plus or minus]pi[superscript plus or minus]pi[superscript minus over plus] using a sample of (465±5)×10[superscript ...
  • Cowan, Ray Franklin; Dujmic, Denis; Sciolla, Gabriella; Zhao, Min Liang (American Physical Society, 2011-03)
    We perform a Dalitz plot analysis of about 100 000 Ds+ [D subscript s superscript +] decays to K+K-π+ [K superscript + K superscript - pi superscript +] and measure the complex amplitudes of the intermediate resonances ...
  • Zhao, M.; Yamamoto, R. K.; Taylor, Frank E.; Spitznagel, M.; Sciolla, Gabriella; Henderson, Shawn Wesley; Dujmic, Denis; Cowan, Ray Franklin; Fisher, Peter H. (American Physical Society, 2009-02)
    A Dalitz plot analysis of approximately 13 000 D[subscript s] + decays to pi + pi - pi + has been performed. The analysis uses a 384   fb-1 data sample recorded by the BABAR detector at the PEP-II asymmetric-energy e+e- ...
  • Cowan, Ray Franklin; Koeneke, Karsten; Sciolla, Gabriella; Sekula, S.J.; Spitznagel, Michael; Yamamoto, Richard K.; Taylor, Frank E. (American Physical Society, 2006-08)
    We analyze the three-body charmless decay B[superscript ±]→K[superscript ±]K[superscript ±]K[superscript ∓] using a sample of 226.0±2.5 million BB̅ pairs collected by the BABAR detector. We measure the total branching ...
  • Cowan, Ray Franklin; Sciolla, Gabriella (American Physical Society, 2014-06)
    We study the processes γγ → K[superscript +]K[superscript −]η and γγ → K[superscript +]K[superscript −]π[superscript 0] using a data sample of 519  fb[superscript −1] recorded with the BABAR detector operating at the SLAC ...
  • Haupt, Robert W.; Yu, Tzu-Yang (SPIE, 2010-04)
    In this paper, a distant acoustic-laser NDE technique is proposed, utilizing a high powered standoff parametric acoustic array (PAA) and laser Doppler vibrometry (LDV), for the detection of debonding and delamination in ...
  • Padhye, Nikhil; Torres, James; Thomas, Levon; Ljubicic, Dean M.; Kassner, Mortiz P.; Slocum, Alexander H.; Hopkins, Brandon James; Greenlee, Alison S. (ASME International, 2014-04)
    Wave-driven reverse osmosis desalination systems can be a cost-effective option for providing a safe and reliable source of drinking water for large coastal communities. Such systems usually require the stabilization of ...
  • D'Eramo, Francesco; Fei, Lin; Thaler, Jesse (IOP Publishing, 2012-03)
    Pure singlets are typically disfavored as dark matter candidates, since they generically have a thermal relic abundance larger than the observed value. In this paper, we propose a new dark matter mechanism called "assimilation", ...
  • Pooley, D.; Blackburne, Jeffrey A.; Rappaport, Saul A.; Schechter, Paul L.; Schwab, Josiah; Wambsganss, J. (American Astronomical Society, 2009-05)
    We determine the most likely dark-matter fraction in the elliptical galaxy quadruply lensing the quasar PG 1115+080 based on analyses of the X-ray fluxes of the individual images in 2000 and 2008. Between the two epochs, ...
  • Fan, JiJi; Thaler, Jesse; Wang, Lian-Tao (Springer Berlin / Heidelberg, 2010-06)
    We consider explicit models of dynamical supersymmetry breaking where dark matter is a 10 – 100 TeV strongly-interacting composite state carrying no standard model quantum numbers. These constructions are simple variants ...
  • Battat, J.B.R.; Ahlen, S.; Chernicoff, M.; Dujmic, D.; Dushkin, A.; Fisher, P.; Henderson, S.; Inglis, A.; Kaboth, A.; Kirsch, L.; Lopez, J.P.; Monroe, J.; Ouyang, H.; Sciolla, G.; Tomita, H.; Wellenstein, H.; Deaconu, Cosmin Stefan (EDP Sciences, 2012-02)
    The Dark Matter Time Projection Chamber collaboration recently reported a dark matter limit obtained with a 10 liter time projection chamber filled with CF[subscript 4] gas. The 10 liter detector was capable of 2D tracking ...
  • Devadas, Srinivas; Lis, Mieszko; Shim, Keun Sup; Cho, Myong Hyon; Khan, Omer; Ren, Pengju (2010)
    We present DARSIM, a parallel, highly configurable, cycle-level network-on-chip simulator based on an ingress-queued wormhole router architecture. The parallel simulation engine offers cycle-accurate as well as periodic ...
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