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Browsing MIT Open Access Articles by Title

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  • Prinn, Ronald G. (National Academy of Sciences (U.S.), 2012-06)
    The global environment is a complex and dynamic system. Earth system modeling is needed to help understand changes in interacting subsystems, elucidate the influence of human activities, and explore possible future changes. ...
  • Fedkiw, Timothy Peter; Lozano, Paulo C. (American Vacuum Society, 2009-11)
    Emission of positive and negative ions is possible when a room temperature molten salt, or ionic liquid, is exposed to a sufficiently high electric field. Ionic liquid ion sources (ILIS) have shown potential to be used ...
  • Davidson, Matthew Allen; Hembrador, Sheena; Yanch, Jacquelyn C.; Olipitz, Werner; Engelward, Bevin P. (Health Physics Society, 2010-05)
    Radiation exposure of humans generally results in low doses delivered at low dose rate. Our limited knowledge of the biological effects of low dose radiation is mainly based on data from the atomic bomb Life Span Study ...
  • Bueno Unzeta, Bruno; Pigeon, G.; Norford, Leslie Keith; Zibouche, K.; Marchadier, C. (Copernicus GmbH, 2012-03)
    The use of air-conditioning systems is expected to increase as a consequence of global-scale and urban-scale climate warming. In order to represent future scenarios of urban climate and building energy consumption, the ...
  • Hanumara, Nevan Clancy; Walsh, Conor James; Slocum, Alexander H.; Seitel, Alexander; Shepard, Jo-Anne; Maier-Hein, Lena; Gupta, Rajiv; Meinzer, Hans-Peter (The International Society for Optical Engineering, 2009-03)
    The main challenges of Computed Tomography (CT)-guided organ puncture are the mental registration of the medical imaging data with the patient anatomy, required when planning a trajectory, and the subsequent precise insertion ...
  • Levin, Joshua; Adiconis, Xian; Yassour, Moran; Thompson, Dawn; Guttman, Mitchell; Berger, Michael; Fan, Lin; Friedman, Nir; Nusbaum, Chad; Gnirke, Andreas; Regev, Aviv (BioMed Central Ltd., 2011-10)
    RNA-seq provides insights at multiple levels into the transcription of the genome as it yields sequence, splicing and expression-level information. We have been developing and comparing a wide range of RNA-seq methods for ...
  • Verma, Rajeev; Del Vecchio, Domitilla (Institute of Electrical and Electronics Engineers, 2011-12)
    In this paper, the problem of collision avoidance between two vehicles is considered, in which one vehicle is autonomous and the other one is human-driven. This problem arises in cooperative active safety systems at traffic ...
  • Theogarajan, Luke; Wyatt, John L; Mendoza, Oscar D.; Rizzo, Joseph F.; Drohan, William A.; Cogan, Stuart F.; Gingerich, Marcus D.; Doyle, Patrick S.; Chen, Jinghua; Kelly, Shawn K.; Shire, Douglas B. (Institute of Electrical and Electronics Engineers, 2009-09)
    A wirelessly operated, minimally invasive retinal prosthesis was developed for preclinical chronic implantation studies in Yucatan minipig models. The implant conforms to the outer wall of the eye and drives a microfabricated ...
  • Langer, Robert; Farokhzad, Omid C.; Gadde, Suresh; Kamaly, Nazila; Fredman, Gabrielle; Subramanian, Manikandan; Pesic, Aleksandar; Cheung, Louis; Fayad, Zahi Adel; Tabas, Ira (National Academy of Sciences (U.S.), 2013-03)
    Excessive inflammation and failed resolution of the inflammatory response are underlying components of numerous conditions such as arthritis, cardiovascular disease, and cancer. Hence, therapeutics that dampen inflammation ...
  • Langer, Robert; Kamaly, Nazila; Fredman, Gabrielle; Subramanian, Manikandan; Gadde, Suresh; Pesic, Alexsandar; Cheung, Louis; Fayad, Zahi Adel; Tabas, Ira; Cameron Farokhzad, Omid (National Academy of Sciences (U.S.), 2013-03)
    Excessive inflammation and failed resolution of the inflammatory response are underlying components of numerous conditions such as arthritis, cardiovascular disease, and cancer. Hence, therapeutics that dampen inflammation ...
  • Stewart, Frank J.; Ottesen, Elizabeth; DeLong, Edward (Nature Publishing Group, 2010-03)
    Metatranscriptomes generated by pyrosequencing hold significant potential for describing functional processes in complex microbial communities. Meeting this potential requires protocols that maximize mRNA recovery by ...
  • Han, Hee-Sun; Devaraj, Neal K.; Lee, Jungmin; Hilderbrand, Scott A.; Weissleder, Ralph; Bawendi, Moungi G. (American Chemical Society, 2010-05)
    We present a bioorthogonal and modular conjugation method for efficient coupling of organic dyes and biomolecules to quantum dots (QDs) using a norbornene−tetrazine cycloaddition. The use of noncoordinating functional ...
  • Smith, Matthew; Schulz, Norbert S.; Schattenburg, Mark Lee; Mukherjee, Pran; Marshall, Herman Lee; Huenemoerder, David P.; Foster, Richard F.; Bautz, Marshall W.; Ahn, Minseung; Heilmann, Ralf K. (The International Society for Optical Engineering, 2009-08)
    We present a high-resolution soft x-ray grating spectrometer concept for the International X-Ray Observatory (IXO) that meets or exceeds the minimum requirements for effective area (> 1, 000 cm[superscript 2] for E < 1 ...
  • Cohen, Jason Blake; Prinn, Ronald G. (European Geosciences Union, 2011-08)
    A reduced form metamodel has been produced to simulate the effects of physical, chemical, and meteorological processing of highly reactive trace species in urban areas, which is capable of efficiently simulating the urban ...
  • Leman, Steven W.; Damayanthi, Rathnayaka Mudiyanselage Thushara; Takahashi, Hiroyuki; Ohno, Masashi; Minamikawa, Yasuhiro; Nishimura, Kentaro; Iyomoto, Naoko (Institute of Electrical and Electronics Engineers, 2009-06)
    We have recently started to develop a high-resolution gamma-ray spectrometer for material defect analysis. Our gamma-ray detector is a microcalorimeter consisting of an iridium/gold bilayer transition edge sensor (TES) ...
  • Romano, Paul Kollath; Forget, Benoit; Newton, Thomas H., Jr. (American Nuclear Society, 2009-04)
    In the present work, a graphical user interface is developed to automate in-core fuel management using MCODE, an MCNP-ORIGEN linkage code. Data abstraction is achieved by means of five object classes that define the run, ...
  • Ljubicic, Dean M.; Anthony, Brian (SPIE, 2010-08)
    Optical digital-imaging techniques offer a fast, high-resolution, and wide-range metrology capability for measuring semi-transparent and transparent polymer-based devices during manufacture. This work presents novel ...
  • Pawl, Andrew; Barrantes, Analia; Cardamone, Carolin; Rayyan, Saif; Pritchard, David E. (American Institute of Physics (AIP), 2012)
    Strategic knowledge is required to appropriately organize procedures and concepts to solve problems. We are developing a standardized instrument assessing strategic knowledge in the domain of introductory mechanics. This ...
  • Goodell, John R.; McMullen, Jonathan P.; Zaborenko, Nikolay; Maloney, Jason R.; Ho, Chuan-Xing; Jensen, Klavs F.; Porco, John A.; Beeler, Aaron B. (American Chemical Society, 2009-08)
    An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo ...
  • Korre, Hasan; Fucetola, Corey P.; Johnson, Jeremiah A.; Berggren, Karl K. (American Vacuum Society (AVS), 2010-12)
    Interference lithography (IL) has proven itself to be an enabling technology for nanofabrication. Within IL, issues of spatial phase distortion, fringe stability, and substrate development have been explored and addressed. ...
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