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Browsing MIT Open Access Articles by Title

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  • Gary, G.; Roth, C. C.; Mohr, Dirk (Springer US, 2015-08)
    A new set-up is proposed to perform high strain rate tension experiments on sheet metal using a compression Hopkinson bar system on the input side. With the help of a custom-made load inversion device, the compression ...
  • Byun, Hyunil; Sander, Michelle Yen-Ling; Motamedi, Ali R.; Shen, Hanfei M.; Petrich, Gale S.; Kolodziejski, Leslie A.; Ippen, Erich P.; Kaertner, Franz X. (Optical Society of America, 2010-10)
    We demonstrate a high-repetition-rate soliton fiber laser that is based on highly-doped anomalously-dispersive erbium-doped fiber. By splicing an 11-mm single mode fiber to the erbium-doped fiber, thermal damage of the ...
  • Tyurikov, Dmitry; Shewmon, Ruth; Benedick, Andrew J.; Kaertner, Franz X.; Gubin, Mikhail; Chuang, Isaac L. (Optical Society of America, 2009-07)
    A compact optical clock and frequency comb system is presented, based on a 1 GHz octave spanning Ti:sapphire laser referenced to the F2[superscript(2)](P(7),v[subscript 3]) optical transition in methane at 3.39 μm. The ...
  • Bessuille, J.; Brown, P.; Carbajo, S.; Dolgashev, Valery A.; Lin, H.; Murari, K.; Resta, G.; Tantawi, S.; Zapata, L. E.; Graves, William S.; Hong, Kyung-Han; Ihloff, Ernest E.; Khaykovich, Boris; Nanni, Emilio Alessandro; Kaertner, Franz X.; Moncton, David E. (American Physical Society, 2014-12)
    A design for a compact x-ray light source (CXLS) with flux and brilliance orders of magnitude beyond existing laboratory scale sources is presented. The source is based on inverse Compton scattering of a high brightness ...
  • Wei, He; Insin, Numpon; Lee, Jungmin; Han, Hee-Sun; Liu, Wenhao; Bawendi, Moungi G.; Cordero Hernandez, Jose M. (American Institute of Physics (AIP), 2011-12)
    The potential of superparamagnetic iron oxide nanoparticles (SPIONs) in various biomedical applications, including magnetic resonance imaging (MRI), sensing, and drug delivery, requires that their surface be derivatized ...
  • Wei, He; Chen, Ou; Bawendi, Moungi G.; Bruns, Oliver Thomas (Royal Society of Chemistry, The, 2012-10)
    We have recently developed compact and water-soluble zwitterionic dopamine sulfonate (ZDS) ligand coated superparamagnetic iron oxide nanoparticles (SPIONs) for use in various biomedical applications. The defining ...
  • Pit-Claudel, Clement F.; Courtieu, Pierre (2016-01)
    Company-Coq is a new Emacs package that extends Proof General with a contextual auto-completion engine for Coq proofs and many additional facilities to make writing proofs easier and more efficient. Beyond fuzzy auto-completion ...
  • Costinot, Arnaud; Donaldson, David John; Vogel, Jonathan; Werning, Ivan (Oxford University Press, 2015-02)
    The theory of comparative advantage is at the core of neoclassical trade theory. Yet we know little about its implications for how nations should conduct their trade policy. For example, should import sectors with weaker ...
  • Wernerfelt, Birger (Wiley Blackwell, 2014-10)
    The most efficient labour market mechanism depends on the advantages of specialization, workers’ costs of switching between entrepreneurs, and the frequency with which needs change. Multilateral mechanisms are more efficient ...
  • Cui, Liang; Ye, Wenjie; Wishnok, John S.; Taghizadeh, Koli; Dedon, Peter C.; Prestwich, Erin; Tannenbaum, Steven Robert (American Chemical Society (ACS), 2012-11)
    Oxidative damage to DNA has many origins, including irradiation, inflammation, and oxidative stress, but the chemistries are not the same. The most oxidizable base in DNA is 2-deoxyguanosine (dG), and the primary oxidation ...
  • Kundaje, Anshul; Kumar, Nischay; Kellis, Manolis; Day, Daniel S. (American Association for the Advancement of Science (AAAS), 2014-08)
    Genome function is dynamically regulated in part by chromatin, which consists of the histones, non-histone proteins and RNA molecules that package DNA. Studies in Caenorhabditis elegans and Drosophila melanogaster have ...
  • Kheradpour, Pouya; Kundaje, Anshul; Wu, Yi-Chieh; Kellis, Manolis (American Association for the Advancement of Science (AAAS), 2014-08)
    Despite the large evolutionary distances between metazoan species, they can show remarkable commonalities in their biology, and this has helped to establish fly and worm as model organisms for human biology. Although studies ...
  • Adiconis, Xian; Borges-Rivera, Diego; Satija, Rahul; DeLuca, David S.; Busby, Michele A.; Berlin, Aaron M.; Sivachenko, Andrey; Thompson, Dawn Anne; Wysoker, Alec; Fennell, Timothy; Gnirke, Andreas; Pochet, Nathalie; Regev, Aviv; Levin, Joshua Z. (Nature Publishing Group, 2013-05)
    RNA-seq is an effective method for studying the transcriptome, but it can be difficult to apply to scarce or degraded RNA from fixed clinical samples, rare cell populations or cadavers. Recent studies have proposed several ...
  • Adiconis, Xian; Borges-Rivera, Diego; Satija, Rahul; DeLuca, David S.; Busby, Michele A.; Berlin, Aaron M.; Sivachenko, Andrey; Thompson, Dawn Anne; Wysoker, Alec; Fennell, Timothy; Gnirke, Andreas; Pochet, Nathalie; Regev, Aviv; Levin, Joshua Z. (Nature Publishing Group, 2013-05)
    RNA-seq is an effective method for studying the transcriptome, but it can be difficult to apply to scarce or degraded RNA from fixed clinical samples, rare cell populations or cadavers. Recent studies have proposed several ...
  • Vaisman, Lev; Krebs, Hermano Igo; Michmizos, Konstantinos (Frontiers Research Foundation, 2014-11)
    Little is known about whether our knowledge of how the central nervous system controls the upper extremities (UE), can generalize, and to what extent to the lower limbs. Our continuous efforts to design the ideal adaptive ...
  • Ghiviriga, Ion; Dancel, Christine; Kodira, Chinnappa D.; Desany, Brian; Affourtit, Jason P.; Abeel, Thomas; Gevers, Dirk; Birren, Bruce W.; Godfrey, Paul; Desjardins, Christopher A.; Holder, Jason W.; DeBono, Tony; Ulrich, Jil; Zucker, Jeremy; Zeng, Qiandong; Leach, Alex L. B.; Sinskey, Anthony J. (Public Library of Science, 2011-09)
    The Actinomycetales bacteria Rhodococcus opacus PD630 and Rhodococcus jostii RHA1 bioconvert a diverse range of organic substrates through lipid biosynthesis into large quantities of energy-rich triacylglycerols (TAGs). ...
  • Landry, Markita P.; Vuković, Lela; Kruss, Sebastian; Bisker Raviv, Gili Hana; Landry, Alexandra M.; Islam, Shahrin; Jain, Rishabh Mahendra; Schulten, Klaus; Strano, Michael S. (American Chemical Society (ACS), 2015-03)
    Noncovalent polymer-single walled carbon nanotube (SWCNT) conjugates have gained recent interest due to their prevalent use as electrochemical and optical sensors, SWCNT-based therapeutics, and for SWCNT separation. However, ...
  • Bourgeois, Florence T.; Murthy, Srinivas; Mandl, Kenneth D. (Public Library of Science, 2012-01)
    Background The $1.1 billion investment in comparative effectiveness research will reshape the evidence-base supporting decisions about treatment effectiveness, safety, and cost. Defining the current prevalence and ...
  • Wu, Yi-Chieh; Rasmussen, Matthew D.; Bansal, Mukul S.; Kellis, Manolis (Nature Publishing Group, 2014-11)
    The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To gain greater insights into ...
  • Agarwal, Abhinav; Ng, Man Cheuk; Mithal, Arvind (Institute of Electrical and Electronics Engineers (IEEE), 2010-07)
    Using the example of a Reed-Solomon decoder, we provide insights into what type of hardware structures are needed to be generated to achieve specific performance targets. Due to the presence of run-time dependencies, ...
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