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Browsing MIT Open Access Articles by Title

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  • Melas, Ioannis N.; Mitsos, Alexander; Messinis, Dimitris E.; Weiss, Thomas S.; Alexopoulos, Leonidas G. (BioMed Central Ltd., 2011-07)
    Background Signalling pathways are the cornerstone on understanding cell function and predicting cell behavior. Recently, logical models of canonical pathways have been optimised with high-throughput phosphoproteomic ...
  • Zhao, Zhigang; Chen, Li; Dawlaty, Meelad M.; Pan, Feng; Weeks, Ophelia; Zhou, Yuan; Cao, Zeng; Shi, Hui; Wang, Jiapeng; Lin, Li; Chen, Shi; Yuan, Weiping; Qin, Zhaohui; Ni, Hongyu; Nimer, Stephen D.; Yang, Feng-Chun; Jaenisch, Rudolf; Jin, Peng; Xu, Mingjiang (Elsevier, 2015-11)
    TET1/2/3 are methylcytosine dioxygenases that regulate cytosine hydroxymethylation. Tet1/2 are abundantly expressed in HSC/HPCs and are implicated in hematological malignancies. Tet2 deletion in mice causes myeloid ...
  • Taylor, Frank E.; Apyan, Aram; Barbieri, Richard Alexander; Baty, Austin Alan; Bierwagen, Katharina; Brandt, Stephanie Akemi; Busza, Wit; Cali, Ivan Amos; Di Matteo, Leonardo; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Gulhan, Doga Can; Innocenti, Gian Michele; Klute, Markus; Kovalskyi, Dmytro; Lai, Yue Shi; Lee, Yen-Jie; Levin, Andrew Michael; Luckey, P. David, Jr.; McGinn, Christopher Francis; Niu, Xinmei; Paus, Christoph M. E.; Ralph, Duncan Kelley; Roland, Christof E.; Roland, Gunther M.; Stephans, George S. F.; Sumorok, Konstanty C.; Varma, Mukund; Velicanu, Dragos Alexandru; Veverka, Jan; Wang, Juven; Wang, Ta-Wei; Wyslouch, Boleslaw; Yang, Mingming; Zhukova, Victoria (American Physical Society, 2015-05)
    A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H → γγ and H → ZZ → 4ℓ decay channels. The results are obtained from a simultaneous ...
  • Toni, Tina; Tidor, Bruce (Public Library of Science, 2013-03)
    Biological systems are inherently variable, with their dynamics influenced by intrinsic and extrinsic sources. These systems are often only partially characterized, with large uncertainties about specific sources of extrinsic ...
  • Zhu, Rong; Buchwald, Stephen Leffler (Wiley Blackwell, 2012-01)
    An efficient protocol has been developed for the intramolecular oxidative oxyarylation using a Pd[superscript II]-catalyzed tandem oxypalladation/C-H functionalization strategy. This methodology allows rapid access to ...
  • Alver, B.; Bauer, Gerry P.; Bendavid, Joshua L.; Busza, Wit; Butz, Erik M.; Cali, Ivan Amos; Chan, M.; Dutta, V.; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Hahn, Kristian Allan; Kim, Y.; Klute, Markus; Lee, Y.-J.; Li, W.; Luckey, P. David, Jr.; Ma, Teng; Nahn, Steven; Paus, Christoph M. E.; Ralph, Duncan Kelley; Roland, Christof E.; Roland, Gunther M.; Rudolph, Matthew Scott; Stephans, George S. F.; Stockli, Fabian; Sumorok, Konstanty C.; Sung, Kevin Kai Hong; Velicanu, Dragos Alexandru; Wenger, Edward Allen; Wolf, R.; Wyslouch, Boleslaw; Xie, S.; Yang, M.; Yilmaz, Yetkin; Yoon, A. S.; Zanetti, Marco (Elsevier, 2012-02)
    Combined results are reported from searches for the standard model Higgs boson in proton–proton collisions at √s = 7 TeV in five Higgs boson decay modes: γγ, bb, ττ , WW, and ZZ. The explored Higgs boson mass range is ...
  • Apyan, Aram; Bauer, Gerry P.; Bendavid, Joshua L.; Busza, Wit; Butz, Erik M.; Cali, Ivan Amos; Chan, M.; Dutta, V.; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Hahn, Kristian Allan; Kim, Y.; Klute, Markus; Krajczar, Krisztian F.; Li, W.; Luckey, P. David, Jr.; Ma, Teng; Nahn, Steven; Paus, Christoph M. E.; Ralph, Duncan Kelley; Roland, Christof E.; Roland, Gunther M.; Rudolph, M.; Stephans, George S. F.; Stockli, Fabian; Sumorok, Konstanty C.; Sung, Kevin Kai Hong; Velicanu, Dragos Alexandru; Wenger, Edward Allen; Wolf, R.; Wyslouch, Boleslaw; Yang, M.; Yilmaz, Yetkin; Yoon, A. S.; Zanetti, Marco (American Physical Society, 2012-12)
    Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5  fb[superscript -1] recorded by the CMS experiment at the LHC ...
  • Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Paus, Christoph M. E. (American Physical Society, 2012-09)
    We combine the results of searches for the standard model (SM) Higgs boson based on the full CDF Run II data set obtained from √s=1.96  TeV pp̅ collisions at the Fermilab Tevatron corresponding to an integrated luminosity ...
  • Taylor, Frank E. (American Physical Society, 2012-08)
    A combined search for the Standard Model Higgs boson with the ATLAS detector at the LHC is presented. The data sets used correspond to integrated luminosities from 4.6  fb[superscript -1] to 4.9  fb[superscript -1] of ...
  • Taylor, Frank E. (Elsevier, 2012-02)
    A combined search for the Standard Model Higgs boson with the ATLAS experiment at the LHC using datasets corresponding to integrated luminosities from 1.04 fb[superscript −1] to 4.9 fb[superscript −1] of pp collisions ...
  • Quinn, David J.; Pivkin, Igor; Wong, Sophie Y.; Chiam, Keng-Hwee; Dao, Ming; Karniadakis, George E.; Suresh, Subra (Springer-Verlag, 2010-12)
    We investigate the biophysical characteristics of healthy human red blood cells (RBCs) traversing microfluidic channels with cross-sectional areas as small as 2.7 × 3 μm. We combine single RBC optical tweezers and flow ...
  • Paus, Christoph M. E.; Bauer, Gerry P.; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Makhoul, K. (American Physical Society, 2010-07)
    We combine results from searches by the CDF and D0 collaborations for a standard model Higgs boson (H) in the process gg-->H-->W+W- in pp̅ collisions at the Fermilab Tevatron Collider at [sqrt]s=1.96  TeV. With 4.8  fb-1 ...
  • Kharraz, Jehad; Arafat, Hassan A.; Warsinger, David Elan Martin; Servi, Amelia T; Van Belleghem, Sarah M.; Gonzalez, Jocelyn V.; Swaminathan, Jaichander; Chung, Hyung Won; Gleason, Karen K; Lienhard, John H. (Elsevier, 2016-01)
    In previous studies of the desalination technology membrane distillation (MD), superhydrophobicity of the membrane has been shown to dramatically decrease fouling in adverse conditions, but the mechanism for this is not ...
  • Demaine, Erik D.; Iacono, John; Langerman, Stefan; Ozkan, Ozgur (Springer-Verlag, 2013-07)
    We present a general transformation for combining a constant number of binary search tree data structures (BSTs) into a single BST whose running time is within a constant factor of the minimum of any “well-behaved” bound ...
  • Zhang, Congqiang; Chen, Xixian; Zou, Ruiyang; Zhou, Kang; Stephanopoulos, Gregory; Too, Heng-Phon (Public Library of Science, 2013-10)
    Isoprenoids are a large and diverse class of compounds that includes many high value natural products and are thus in great demand. To meet the increasing demand for isoprenoid compounds, metabolic engineering of microbes ...
  • Parayil Kumaran, Ajikumar; Leonard, Effendi; Prather, Kristala L. Jones; Stephanopoulos, Gregory; Xiao, Wen-Hai; Tidor, Bruce; Mo, Jeffrey David; Thayer, Kelly Marie (National Academy of Sciences, 2010-07)
    A common strategy of metabolic engineering is to increase the endogenous supply of precursor metabolites to improve pathway productivity. The ability to further enhance heterologous production of a desired compound may be ...
  • Schrater, Paul R.; Legge, Gordon E.; Kalia, Amy Ashwin (Public Library of Science, 2013-09)
    This study investigated the interaction between remembered landmark and path integration strategies for estimating current location when walking in an environment without vision. We asked whether observers navigating without ...
  • Ou, Wanmei; Wells, William M.; Golland, Polina (Elsevier, 2010-03)
    In this paper, we analyze Markov Random Field (MRF) as a spatial regularizer in fMRI detection. The low signal-to-noise ratio (SNR) in fMRI images presents a serious challenge for detection algorithms, making regularization ...
  • Chao, John C.; Hausman, Jerry A.; Newey, Whitney K.; Swanson, Norman R.; Woutersen, Tiemen (Emerald (MCB UP), 2012)
    This chapter shows how a weighted average of a forward and reverse Jackknife IV estimator (JIVE) yields estimators that are robust against heteroscedasticity and many instruments. These estimators, called HFUL (Heteroscedasticity ...
  • Roberts, Richard J.; Chang, Yi-Chien; Hu, Zhenjun; Rachlin, John N.; Anton, Brian P.; Pokrzywa, Revonda M.; Choi, Han-Pil; Faller, Lina L.; Guleria, Jyotsna; Housman, Genevieve; Klitgord, Niels; Mazumdar, Varun; McGettrick, Mark G.; Osmani, Lais; Swaminathan, Rajeswari; Tao, Kevin R.; Letovsky, Stan; Vitkup, Dennis; Segrè, Daniel; Salzber, Steven L.; Delisi, Charles; Steffen, Martin; Kasif, Simon (Oxford University Press (OUP), 2010-11)
    COMBREX (http://combrex.bu.edu) is a project to increase the speed of the functional annotation of new bacterial and archaeal genomes. It consists of a database of functional predictions produced by computational biologists ...
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