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Browsing MIT Open Access Articles by Title

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  • Yorukoglu, Deniz; Hac, Faraz; Swanson, Lucas; Collins, Colin C.; Birol, Inanc; Sahinalp, S. Cenk (Oxford University Press, 2012)
    Motivation: Computational identification of genomic structural variants via high-throughput sequencing is an important problem for which a number of highly sophisticated solutions have been recently developed. With the ...
  • Lage, Kasper; Møllgård, Kjeld; Greenway, Steven; Wakimoto, Hiroko; Gorham, Joshua M.; Workman, Christopher T.; Bendsen, Eske; Hansen, Niclas T.; Rigina, Olga; Roque, Francisco S.; Wiese, Cornelia; Christoffels, Vincent M.; Roberts, Amy E.; Smoot, Leslie B.; Pu, William T.; Donahoe, Patricia; Tommerup, Niels; Brunak, Søren; Seidman, Christine E.; Seidman, Jonathan G.; Larsen, Lars A. (Nature Publishing Group / European Molecular Biology Organization (EMBO), 2010-06)
    Aberrant organ development is associated with a wide spectrum of disorders, from schizophrenia to congenital heart disease, but systems-level insight into the underlying processes is very limited. Using heart morphogenesis ...
  • Dalla Torre, Emanuele G.; Otterbach, Johannes; Demler, Eugene; Vuletic, Vladan; Lukin, Mikhail D. (American Physical Society, 2013-03)
    We present and analyze a new approach for the generation of atomic spin-squeezed states. Our method involves the collective coupling of an atomic ensemble to a decaying mode of an open optical cavity. We demonstrate the ...
  • Ahveninen, Jyrki; Jaaskelainen, Iiro P.; Belliveau, John W.; Hamalainen, Matti S.; Lin, Fa-Hsuan; Raij, Tommi (Public Library of Science, 2012-06)
    Given that both auditory and visual systems have anatomically separate object identification (“what”) and spatial (“where”) pathways, it is of interest whether attention-driven cross-sensory modulations occur separately ...
  • Cloutier, Jasmin; Powell, Lindsey J.; Macrae, C. Neil; Metcalfe, Janet; Mitchell, Jason P. (MIT Press, 2010-10)
    Although humans generally experience a coherent sense of selfhood, we can nevertheless articulate different aspects of self. Recent research has demonstrated that one such aspect of self—conceptual knowledge of one's own ...
  • Gabrieli, John D. E.; Moran, Joseph M.; Lee, Su Mei (MIT Press, 2010-10)
    Functional neuroimaging has identified a neural system comprised of posterior cingulate (pCC) and medial prefrontal (mPFC) cortices that appears to mediate self-referential thought. It is unclear whether the two components ...
  • Braida, Louis D; Dykstra, Andrew Richard; Koh, Christine K.; Tramo, Mark Jude (Public Library of Science, 2012-09)
    It is well known that damage to the peripheral auditory system causes deficits in tone detection as well as pitch and loudness perception across a wide range of frequencies. However, the extent to which to which the auditory ...
  • Thorsen, Todd A.; Beretta, Gian Paolo; Poesio, Pietro (American Physical Society, 2009-08)
    A droplet placed in a liquid-liquid solution is expected to grow, or shrink, in time as ∼t[superscript 1/2]. In this Letter, we report experimental evidence that when the composition in the interface is far from thermodynamic ...
  • Jansen, An; van der Zande, Elisa; Meert, Wim; Fink, Gerald R.; Verstrepen, Kevin J. (Oxford University Press (OUP), 2012-01)
    The positions of nucleosomes across the genome influence several cellular processes, including gene transcription. However, our understanding of the factors dictating where nucleosomes are located and how this affects gene ...
  • Wang, Danhua; Turitsyn, Konstantin; Chertkov, Michael (Institute of Electrical and Electronics Engineers, 2012-12)
    We consider a linear feeder connecting multiple distributed loads and generators to the sub-station. Voltage is controlled directly at the sub-station, however, voltage down the line shifts up or down, in particular depending ...
  • Haslam, Bryan Todd; Gordhandas, Ankit; Ricciardi, Catherine; Verghese, George C.; Heldt, Thomas (2011-08)
    Medical electronic systems are generating ever larger data sets from a variety of sensors and devices. Such systems are also being packaged in wearable designs for easy and broad use. The large volume of data and the ...
  • Shabalina, Svetlana A.; Ogurtsov, Aleksey Y.; Spiridonov, Alexey Nikolaevich; Novichkov, Pavel S.; Spiridonov, Nikolay A.; Koonin, Eugene V. (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2010-04)
    Comparison of expression levels and breadth and evolutionary rates of intronless and intron-containing mammalian genes shows that intronless genes are expressed at lower levels, tend to be tissue specific, and evolve ...
  • Dragoi, George; Tonegawa, Susumu (National Academy of Sciences (U.S.), 2013-05)
    The activity of ensembles of hippocampal place cells represents a hallmark of an animal’s spatial experience. The neuronal mechanisms that enable the rapid expression of novel place cell sequences are not entirely understood. ...
  • Vieux (Kloss), Ellen; Wohlever, Matthew Lee; Chen, James Z.; Sauer, Robert T.; Baker, Tania (National Academy of Sciences (U.S.), 2013-05)
    Lon is an ATPase associated with cellular activities (AAA+) protease that controls cell division in response to stress and also degrades misfolded and damaged proteins. Subunits of Lon are known to assemble into ring-shaped ...
  • Triantafyllou, Christina; Brown, Emery N.; Whitfield-Gabrieli, Susan; Scholz, Jonathan; Saxe, Rebecca R. (Public Library of Science, 2009-03)
    In functional magnetic resonance imaging (fMRI) studies, a cortical region in the right temporo-parietal junction (RTPJ) is recruited when participants read stories about people's thoughts (‘Theory of Mind’). Both fMRI and ...
  • McLaughlin, Nathan; Foster, Kelly A.; Edbauer, Dieter; Phillips, Marnie A.; Bolton, Andrew Donald; Constantine-Paton, Martha; Sheng, Morgan Hwa-Tze (Society for Neuroscience, 2010-02)
    NMDA receptors (NMDARs) are critical mediators of activity-dependent synaptic plasticity, but the differential roles of NR2A- versus NR2B-containing NMDARs have been controversial. Here, we investigate the roles of NR2A ...
  • Gordan, Raluca; Hartemink, Alexander J.; Bulyk, Martha L. (Cold Spring Harbor Laboratory Press, 2009-08)
    Transcriptional regulation is largely enacted by transcription factors (TFs) binding DNA. Large numbers of TF binding motifs have been revealed by ChIP-chip experiments followed by computational DNA motif discovery. However, ...
  • Aral, Sinan; Sundararajan, Arun; Muchnik, Lev (National Academy of Sciences, 2009-12)
    Node characteristics and behaviors are often correlated with the structure of social networks over time. While evidence of this type of assortative mixing and temporal clustering of behaviors among linked nodes is used to ...
  • Gallagher, Gillian; Coon Burgess, Jessica Louise (Springer Science + Business Media B.V., 2009-08)
    This paper argues that long-distance assimilations between consonants come in two varieties: Total identity, which arises via a non-local relation between the interacting segments; and partial identity, which results from ...
  • Pavone, Marco; Arsie, Alessandro; Frazzoli, Emilio; Bullo, Francesco (Institute of Electrical and Electronics Engineers (IEEE), 2011-08)
    A widely applied strategy for workload sharing is to equalize the workload assigned to each resource. In mobile multiagent systems, this principle directly leads to equitable partitioning policies whereby: 1) the environment ...
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