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Browsing MIT Open Access Articles by Title

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  • Stojanovic, Vladimir Marko; Joshi, Ajay J.; Batten, Christopher; Kwon, Yong-Jin; Beamer, Scott; Chen, Sun; Asanovic, Krste (Institute of Electrical and Electronics Engineers (IEEE), 2010-05)
    Monolithically integrated dense WDM photonic network topologies optimized for loss and power footprint of optical components can achieve up to 4x better energy-efficiency and throughput than electrical interconnects in ...
  • Shim, Keun Sup; Lis, Mieszko; Cho, Myong Hyon; Devadas, Srinivas; Lebedev, Ilia A. (Institute of Electrical and Electronics Engineers (IEEE), 2013-10)
    As transistor technology continues to scale, the architecture community has experienced exponential growth in design complexity and significantly increasing implementation and verification costs. Moreover, Moore's law has ...
  • Maiti, Panchanan; Lomakin, Aleksey; Benedek, George B.; Bitan, Gal (Wiley Blackwell, 2010-06)
    An important component of the pathologic process underlying Alzheimer’s disease is oxidative stress. Met[superscript 35] in amyloid β-protein (Aβ) is prone to participating in redox reactions promoting oxidative stress, ...
  • Limaye, Ajay B. S.; Aharonson, Oded; Perron, J. Taylor (American Geophysical Union (AGU), 2012-06)
    The Mars polar layered deposits (PLD) likely hold an extensive record of recent climate during a period of high-amplitude orbit and obliquity cycles. Previous work has detected limited evidence for orbital signatures within ...
  • Mitschang, Arik W.; Schulz, Norbert S.; Huenemoerder, David P.; Nichols, Joy S.; Testa, Paola; Huenemoerder, David P. (Institute of Physics/American Astronomical Society, 2011-06)
    We investigate X-ray emission properties of the peculiar X-ray source θ[superscript 2] Ori A in the Orion Trapezium region using more than 500 ks of HETGS spectral data in the quiescent state. The amount of exposure provides ...
  • Sharp, Phillip A.; Boutz, Paul; Bhutkar, Arjun (AJ) (Cold Spring Harbor Laboratory Press, 2015-01)
    Deep sequencing of embryonic stem cell RNA revealed many specific internal introns that are significantly more abundant than the other introns within polyadenylated transcripts; we classified these as “detained” introns ...
  • Carter, Joshua Adam; Winn, Joshua Nathan (Institute of Physics, 2010-05)
    Knowledge of an exoplanet's oblateness and obliquity would give clues about its formation and internal structure. In principle, a light curve of a transiting planet bears information about the planet's shape, but previous ...
  • Carbin, Michael James; Misailovic, Sasa; Kling, Michael W.; Rinard, Martin C. (Springer Berlin / Heidelberg, 2011-07)
    Infinite loops can make applications unresponsive. Potential problems include lost work or output, denied access to application functionality, and a lack of responses to urgent events. We present Jolt, a novel system for ...
  • Tonzetich, Zachary J.; McQuade, Lindsey E.; Lippard, Stephen J. (American Chemical Society (ACS), 2010-07)
    We are pursuing a dual strategy for investigating the chemistry of nitric oxide as a biological signaling agent. In one approach, metal-based fluorescent sensors for the detection of NO in living cells are evaluated, and ...
  • Fish, Vincent L.; Doeleman, Sheperd Samuel; Broderick, Avery E.; Loeb, Abraham; Rogers, Alan E. E. (IOP Publishing, 2009-11)
    Sagittarius A* is the source of near infrared, X-ray, radio, and (sub)millimeter emission associated with the supermassive black hole at the Galactic Center. In the submillimeter regime, Sgr A* exhibits time-variable linear ...
  • Qi, Yang; Fu, Liang (American Physical Society, 2015-03)
    In quantum spin liquid states, the fractionalized spinon excitations can carry fractional crystal symmetry quantum numbers, and this symmetry fractionalization distinguishes different symmetry-enriched spin liquid states ...
  • Sweet, Andrew; Venkataraman, Archana; Stufflebeam, Steven M.; Liu, Hesheng; Tanaka, Naoro; Madsen, Joseph R.; Golland, Polina (Springer-Verlag Berlin Heidelberg, 2013)
    We present a method to detect epileptic regions based on functional connectivity differences between individual epilepsy patients and a healthy population. Our model assumes that the global functional characteristics of ...
  • Doeleman, Sheperd Samuel; Fish, Vincent L.; Broderick, Avery E.; Loeb, Abraham; Rogers, Alan E. E. (Institute of Physics/American Astronomical Society, 2009-04)
    The super-massive black hole candidate, Sagittarius A*, exhibits variability from radio to X-ray wavelengths on timescales that correspond to <10 Schwarzschild radii. We survey the potential of millimeter wavelength very ...
  • Bansal, Mukul S.; Banay, Guy; Gogarten, J. Peter; Shamir, Ron (Mary Ann Liebert, Inc., 2011-09)
    In a horizontal gene transfer (HGT) event, a gene is transferred between two species that do not have an ancestor-descendant relationship. Typically, no more than a few genes are horizontally transferred between any two ...
  • Cheow, Lih Feng; Sarkar, Aniruddh; Kolitz, Sarah; Han, Jongyoon; Lauffenburger, Douglas A. (American Chemical Society (ACS), 2014-07)
    Electrokinetic preconcentration coupled with mobility shift assays can give rise to very high detection sensitivities. We describe a microfluidic device that utilizes this principle to detect cellular kinase activities by ...
  • Savoie, Troy B.; Frey, Daniel (Springer-Verlag, 2011-11)
    This paper presents the results of an experiment with human subjects investigating their ability to discover a mistake in a model used for engineering design. For the purpose of this study, a known mistake was intentionally ...
  • Reshef, David N.; Reshef, Yakir; Grossman, Sharon Rachel; Lander, Eric S.; Finucane, Hilary Kiyo; McVean, Gilean; Turnbaugh, Peter J.; Mitzenmacher, Michael; Sabeti, Pardis C. (American Association for the Advancement of Science (AAAS), 2011-12)
    Identifying interesting relationships between pairs of variables in large data sets is increasingly important. Here, we present a measure of dependence for two-variable relationships: the maximal information coefficient ...
  • Chaturvedi, Iti; Rajapakse, Jagath (BioMed Central Ltd, 2009-12)
    Background: Time delays are often found in gene regulation though most techniques of building gene regulatory networks are not capable of capturing such phenomena. Here we look at the delays in the DNA repair system of ...
  • Shah, Devavrat; Zaman, Tauhid R. (Association for Computing Machinery, 2010-06)
    We provide a systematic study of the problem of finding the source of a computer virus in a network. We model virus spreading in a network with a variant of the popular SIR model and then construct an estimator for the ...
  • Langs, Georg; Menze, Bjoern H.; Lashkari, Danial; Golland, Polina (Elsevier, 2010-08)
    The relationship between spatially distributed fMRI patterns and experimental stimuli or tasks offers insights into cognitive processes beyond those traceable from individual local activations. The multivariate properties ...
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