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Browsing MIT Open Access Articles by Title

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  • Rajni Swamy, V.; Gunasekaran, P.; Krishnakumar, R. V.; Srinivasan, N.; Mueller, Peter (International Union of Crystallography (IUCr), 2014-08)
    The title compound, C[subscript 26]H[subscript 18]F[subscript 3]N[subscript 3]O[subscript 2]S, a 2-meth­oxy-substituted derivative, is closely related to its 4-methyl- and 4-chloro-substituted analogues and yet displays ...
  • Rich, Alexander; de Rosa, Matteo; de Sanctis, Daniele; Rosario, Ana Lucia; Archer, Margarida; Athanasiadis, Alekos; Carrondo, Maria Armenia (National Academy of Sciences, 2010-05)
    The double helix of DNA, when composed of dinucleotide purine-pyrimidine repeats, can adopt a left-handed helical structure called Z-DNA. For reasons not entirely understood, such dinucleotide repeats in genomic sequences ...
  • Schmidt, Michael M.; Townson, Sharon A.; Andreucci, Amy J.; King, Bracken Matheny; Schirmer, Emily B.; Murillo, Alec J.; Dombrowski, Christian; Tisdale, Alison W.; Lowden, Patricia A.; Masci, Allyson L.; Kovalchin, Joseph T.; Erbe, David V.; Wittrup, Karl Dane; Furfine, Eric S.; Barnes, Thomas M. (Elsevier B.V., 2013-11)
    The long circulating half-life of serum albumin, the most abundant protein in mammalian plasma, derives from pH-dependent endosomal salvage from degradation, mediated by the neonatal Fc receptor (FcRn). Using yeast display, ...
  • Deshpande, Chandrika N.; Harrop, Stephen J.; Boucher, Yan; Hassan, Karl A.; Di Leo, Rosa; Xu, Xiaohui; Cui, Hong; Savchenko, Alexei; Chang, Changsoo; Labbate, Maurizio; Paulsen, Ian T.; Stokes, H. W.; Curmi, Paul M. G.; Mabbutt, Bridget C. (Public Library of Science, 2011-03)
    Background The direct isolation of integron gene cassettes from cultivated and environmental microbial sources allows an assessment of the impact of the integron/gene cassette system on the emergence of new phenotypes, ...
  • Schmitz, Karl R.; Carney, Daniel W.; Sello, Jason K.; Sauer, Robert T. (National Academy of Sciences (U.S.), 2014-09)
    Caseinolytic peptidase P (ClpP), a double-ring peptidase with 14 subunits, collaborates with ATPases associated with diverse activities (AAA+) partners to execute ATP-dependent protein degradation. Although many ClpP enzymes ...
  • Glynn, Steven E.; Martin, Andreas; Nager, Andrew Ross; Baker, Tania; Sauer, Robert T. (Elsevier, 2009-11)
    ClpX is a AAA+ machine that uses the energy of ATP binding and hydrolysis to unfold native proteins and translocate unfolded polypeptides into the ClpP peptidase. The crystal structures presented here reveal striking ...
  • Backer, Chelsea B.; Gutzman, Jennifer H.; Pearson, Chad G.; Cheeseman, Iain McPherson (American Society for Cell Biology, 2012-04)
    The diverse populations of microtubule polymers in cells are functionally distinguished by different posttranslational modifications, including polyglutamylation. Polyglutamylation is enriched on subsets of microtubules ...
  • Li, Yang; Wilson, Justin J.; Do, Loi Hung; Apfel, Ulf-Peter; Lippard, Stephen J. (Royal Society of Chemistry, The, 2012-06)
    A triptycene-based bis(benzoxazole) diacid ligand H[subscript 2]L2[superscript Ph4] bearing sterically encumbering groups was synthesized. Treatment of H[subscript 2]L2[superscript Ph4] with Fe(OTf)[subscript 3] afforded ...
  • Beigi, Salman; Shor, Peter W. (Rinton Press, 2010-01)
    Fault-tolerant quantum computation is a basic problem in quantum computation, andteleportation is one of the main techniques in this theory. Using teleportation on stabi-lizer codes, the most well-known quantum codes, Pauli ...
  • Luna, Rafael E.; Arthanari, Haribabu; Hiraishi, Hiroyuki; Nanda, Jagpreet; Martin-Marcos, Pilar; Markus, Michelle A.; Akabayov, Barak; Milbradt, Alexander G.; Luna, Lunet E.; Seo, Hee-Chan; Hyberts, Sven G.; Fahmy, Amr; Reibarkh, Mikhail; Miles, David; Hagner, Patrick R.; O'Day, Elizabeth M.; Yi, Tingfang; Marintchev, Assen; Hinnebusch, Alan G.; Lorsch, Jon R.; Asano, Katsura; Wagner, Gerhard (Elsevier, 2012-05)
    Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves eukaryotic initiation factors (eIFs) eIF1, eIF1A, eIF2, and eIF5. The carboxyl terminal domain (CTD) ...
  • Liu, Hui; Ong, Shao-En; Badu-Nkansah, Kwabena; Schindler, Jeffrey W.; White, Forest M.; Hynes, Richard O. (National Academy of Sciences (U.S.), 2011-01)
    We report the application of quantitative mass spectrometry to identify plasma membrane proteins differentially expressed in melanoma cells with high vs. low metastatic abilities. Using stable isotope labeling with amino ...
  • Cahoy, Kerri; Cheng, Kezi; Jamil, Sara; Marinan, Anne D.; Kerr, Caitlin E. (2012-08)
    The goal of the CubeSat Deformable Mirror Demonstration (DeMi) is to characterize the performance of a small deformable mirror over a year in low-Earth orbit. Small form factor deformable mirrors are a key technology needed ...
  • Lee, Yang; Madnick, Stuart E.; Wang, Richard Y.; Wang, Forea; Zhang, Hongyun (Management Information Systems Research Center, Carlson School of Management, University of Minnesota, 2014-03)
    A new breed of executive, the chief data officer (CDO), is emerging as a key leader in the organization. We provide a three-dimensional cubic framework that describes the role of the CDO. The three dimensions are: (1) ...
  • Maiti, Debabrata; Buchwald, Stephen Leffler (American Chemical Society, 2010-02)
    Cu-catalyzed O-arylation of phenols with aryl iodides and bromides can be performed under mild condition in DMSO/K3PO4 with use of picolinic acid as the ligand for copper. This method tolerates a variety of functional ...
  • Jones, Stephanie R.; Kerr, Catherine E.; Hamalainen, Matti S.; Wan, Qian; Pritchett, Dominique Leon; Moore, Christopher I. (Society for Neuroscience, 2010-10)
    Cued spatial attention modulates functionally relevant alpha rhythms in visual cortices in humans. Here, we present evidence for analogous phenomena in primary somatosensory neocortex (SI). Using magnetoencephalography, ...
  • Honisch, Juliane J.; Elliott, Mark T.; Jacoby, Nori; Wing, Alan M. (Nature Publishing Group, 2016-01)
    To maintain synchrony in group activities, each individual within the group must continuously correct their movements to remain in time with the temporal cues available. Cues might originate from one or more members of the ...
  • Yoon, Jennifer M. D.; Witthoft, Nathan; Winawer, Jonathan; Frank, Michael C.; Everett, Daniel L.; Gibson, Edward A. (Public Library of Science, 2014-11)
    Visual illusions and other perceptual phenomena can be used as tools to uncover the otherwise hidden constructive processes that give rise to perception. Although many perceptual processes are assumed to be universal, ...
  • Filipsson, H. L.; Bernhard, J. M.; Lincoln, Sara Ann; McCorkle, D. C. (Copernicus Publications on behalf of the European Geophysical Society, 2010-04)
    Benthic foraminifera were cultured for five months at four temperatures (4, 7, 14 and 21 °C) to establish the temperature dependence of foraminiferal calcite δ18O and Mg/Ca. Two Bulimina species (B. aculeata and B. marginata) ...
  • Lam, Raymond H. W.; Thorsen, Todd A.; Kim, Min-Cheol (American Chemical Society, 2009-07)
    In this manuscript, we report on the culture of anaerobic and aerobic species within a disposable multilayer polydimethylsiloxane (PDMS) microfluidic device with an integrated differential oxygenator. A gas-filled microchannel ...
  • Ligi, C.; Alduino, C.; Alessandria, F.; Biassoni, M.; Bucci, C.; Caminata, A.; Canonica, L.; Cappelli, L.; Chott, N. I; Copello, S.; D’Addabbo, A.; Dell’Oro, S.; Drobizhev, A.; Franceschi, M. A; Gorla, P.; Napolitano, T.; Nucciotti, A.; Orlandi, D.; Pagliarone, C.; Pattavina, L.; Rusconi, C.; Santone, D.; Singh, V.; Taffarello, L.; Terranova, F.; Uttaro, S.; Chott, N. I.; Franceschi, M. A.; Gladstone, Laura; Ouellet, Jonathan L (Springer US, 2015-12)
    The cryogenic underground observatory for rare events (CUORE) is a 1-ton scale bolometric experiment whose detector consists of an array of 988 TeO[subscript 2] crystals arranged in a cylindrical compact structure of 19 ...
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