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Browsing MIT Open Access Articles by Title

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  • Amon, Angelika B.; Tyers, Mike (Elsevier Ltd., 2009-12)
    Cells must perpetually decide on three big choices in life: to grow, to divide or to die. These system-level decisions are the output of a complex and still very poorly understood molecular algorithm, which is built from ...
  • Klann, Jeffrey G.; Szolovits, Peter; Downs, Stephen M.; Schadow, Gunther (Elsevier, 2013-12)
    Objective Reducing care variability through guidelines has significantly benefited patients. Nonetheless, guideline-based Clinical Decision Support (CDS) systems are not widely implemented or used, are frequently out-of-date, ...
  • Sandberg, Melanie J.; Simaiakis, Ioannis; Balakrishnan, Hamsa; Reynolds, Thomas G.; Hansman, Robert J., Jr. (Institute of Electrical and Electronics Engineers (IEEE), 2014-05)
    Airport surface congestion control has the potential to mitigate the increase in taxi times and fuel burn at major airports. One possible class of congestion control strategies predicts the departure throughput, and ...
  • Kharait, Sourabh; Hautaniemi, Sampsa; Wu, Shan; Iwabu, Akihiro; Lauffenburger, Douglas A.; Wells, Alan (BioMed Central Ltd, 2007-01)
    Background: Computational models of cell signaling networks typically are aimed at capturing dynamics of molecular components to derive quantitative insights from prior experimental data, and to make predictions concerning ...
  • Shaevitz, M. H.; Axani, Spencer Nicholas; Collin, Gabriel Lewis; Conrad, Janet; Spitz, Joshua B.; Wongjirad, Taritree (American Physical Society, 2015-11)
    “KPipe” is a proposed experiment which will study muon neutrino disappearance for a sensitive test of the Δm[superscript 2] ~ 1  eV[superscript 2] anomalies, possibly indicative of one or more sterile neutrinos. The ...
  • Youngman, Matthew J.; Rogers, Zoe N.; Kim, Dennis H. (Public Library of Science, 2011-05)
    The decline in immune function with aging, known as immunosenescence, has been implicated in evolutionarily diverse species, but the underlying molecular mechanisms are not understood. During aging in Caenorhabditis elegans, ...
  • Tikekar, Mehul; Huang, Chao-Tsung; Sze, Vivienne; Juvekar, Chiraag Shashikant; Chandrakasan, Anantha P. (Springer-Verlag, 2014)
    This chapter provides an overview of the design challenges faced in the implementation of hardware HEVC decoders. These challenges can be attributed to the larger and diverse coding block sizes and transform sizes, the ...
  • Koster-Hale, Jorie; Saxe, Rebecca R.; Dungan, James; Young, Liane L. (National Academy of Sciences (U.S.), 2013-03)
    Intentional harms are typically judged to be morally worse than accidental harms. Distinguishing between intentional harms and accidents depends on the capacity for mental state reasoning (i.e., reasoning about beliefs and ...
  • Matthews, Gillian A.; Presbrey, Kara N.; Wichmann, Romy; Wildes, Craig P.; Nieh, Horng-An Edward; Allsop, Stephen Azariah; Leppla, Christopher Albert; Neve, Rachael L.; Tye, Kay; Matthews, Gillian A.; Presbrey, Kara N.; Wildes, Craig P. (Elsevier, 2015-01)
    The lateral hypothalamic (LH) projection to the ventral tegmental area (VTA) has been linked to reward processing, but the computations within the LH-VTA loop that give rise to specific aspects of behavior have been difficult ...
  • Pan, Wei; Altshuler, Yaniv; Pentland, Alex Paul (Institute of Electrical and Electronics Engineers (IEEE), 2012-09)
    In this paper, we study roles of social mechanisms in a financial system. Our data come from a novel on-line foreign exchange trading brokerage for individual investors, which also allows investors to form social network ...
  • Day, Mitchell L.; Delgutte, Bertrand (Society for Neuroscience, 2013-10)
    The strategies by which the central nervous system decodes the properties of sensory stimuli, such as sound source location, from the responses of a population of neurons are a matter of debate. We show, using the average ...
  • Jayaraman, Akila; Chandrasekaran, Aarthi; Viswanathan, Karthik; Raman, Rahul; Fox, James G.; Sasisekharan, Ram (Public Library of Science, 2012-02)
    Ferrets are widely used as animal models for studying influenza A viral pathogenesis and transmissibility. Human-adapted influenza A viruses primarily target the upper respiratory tract in humans (infection of the lower ...
  • Kwee, Patrick; Miller, John; Isogai, Tomoki; Barsotti, Lisa; Evans, Matthew J. (American Physical Society, 2014-09)
    Squeezed states of light have been successfully employed in interferometric gravitational-wave detectors to reduce quantum noise, thus becoming one of the most promising options for extending the astrophysical reach of the ...
  • Pushin, Dmitry; Arif, M.; Cory, David G. (American Physical Society, 2009-05)
    Perfect single-crystal neutron interferometers are adversely sensitive to environmental disturbances, particularly mechanical vibrations. The sensitivity to vibrations results from the slow velocity of thermal neutrons and ...
  • Prokopec, Tomislav; Schmidt, Michael G.; Koksma, Jurjen Ferdinand (American Physical Society, 2011-04)
    We study the decoherence of a renormalized quantum field theoretical system. We consider our novel correlator approach to decoherence where entropy is generated by neglecting observationally inaccessible correlators. Using ...
  • Todadri, Senthil; Mross, David Fabian (American Physical Society (APS), 2011-10)
    We present a theoretical approach to describing the Mott transition of electrons on a two-dimensional lattice that begins with the low-energy effective theory of the Fermi liquid. The approach to the Mott transition must ...
  • Khabbazian, Majid; Kowalski, Dariusz R.; Kuhn, Fabian; Lynch, Nancy Ann (Association for Computing Machinery, 2010-09)
    In much of the theoretical literature on wireless algorithms, issues of message dissemination are considered together with issues of contention management. This combination leads to complicated algorithms and analysis, ...
  • Wu, Di; O'Toole, Matthew; Velten, Andreas; Agrawal, Amit; Raskar, Ramesh (Institute of Electrical and Electronics Engineers, 2012-06)
    Global light transport is composed of direct and indirect components. In this paper, we take the first steps toward analyzing light transport using high temporal resolution information via time of flight (ToF) images. The ...
  • Marla, Lavanya; Barnhart, Cynthia; Biyani, Varun (Springer-Verlag, 2013-02)
    We consider a special class of large-scale, network-based, resource allocation problems under uncertainty, namely that of multi-commodity flows with time-windows under uncertainty. In this class, we focus on problems ...
  • Demaine, Erik D.; Hajiaghayi, Mohammad Taghi; Kawarabayashi, Ken-ichi (Association for Computing Machinery / Society for Industrial and Applied Mathematics, 2010-01)
    We prove two structural decomposition theorems about graphs excluding a fixed odd minor H, and show how these theorems can be used to obtain approximation algorithms for several algorithmic problems in such graphs. Our ...
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