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Browsing MIT Open Access Articles by Title

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  • Liu, Mingna; Lewis, Laura D.; Shi, Rebecca D.; Brown, Emery N.; Xu, Weifeng (American Physiological Society, 2013-11)
    PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using ...
  • Kruger, Juliane M.; Favaro, Plinio D.; Liu, Mingna; Kitlinska, Agata; Huang, Xiaojie; Raabe, Monika; Akad, Derya S.; Liu, Yanling; Urlaub, Henning; Dong, Yan; Xu, Weifeng; Schluter, Oliver M. (Society for Neuroscience, 2013-09)
    In the postsynaptic density of glutamatergic synapses, the discs large (DLG)-membrane-associated guanylate kinase (MAGUK) family of scaffolding proteins coordinates a multiplicity of signaling pathways to maintain and ...
  • Kitamura, Takashi; Tonegawa, Susumu; Sarinana, Joshua; Kunzler, Patrik; Sultzman, Lisa (National Academy of Sciences (U.S.), 2014-05)
    Pharmacological and global KO studies have worked to elucidate the function of dopamine 1-class receptors (D1Rs and D5Rs) in hippocampal-dependent learning and memory. Yet, these manipulations are unable to restrict D1R ...
  • Li, Carman Man Chung; Chen, Guoan; Dayton, Talya Lucia; Kim-Kiselak, Caroline; Hoersch, Sebastian; Whittaker, Charles A.; Bronson, Roderick T.; Beer, David G.; Winslow, Monte M.; Jacks, Tyler E. (Cold Spring Harbor Laboratory Press, 2013-07)
    Metastasis accounts for the vast majority of cancer-related deaths, yet the molecular mechanisms that drive metastatic spread remain poorly understood. Here we report that Tks5, which has been linked to the formation of ...
  • Taylor, Frank E. (Springer-Verlag, 2015-06)
    Various differential cross-sections are measured in top-quark pair (t[bar over t]) events produced in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the LHC with the ATLAS detector. These differential ...
  • Garcia, Alexis; Muthupalani, Sureshkumar; Swennes, Alton G.; Fox, James G.; Shringi, Smriti; Lahmers, Kevin K.; Potter, Kathleen A.; Hovde, Carolyn J.; Call, Douglas R.; Besser, Thomas E. (American Society for Microbiology, 2011-10)
    Enterohemorrhagic Escherichia coli O157:H7 (EHEC O157) is an important cause of food and waterborne illness in the developed countries. Cattle are a reservoir host of EHEC O157 and a major source of human exposure through ...
  • Hrvatin, Sinisa; O'Donnell, Charles W.; Deng, Francis; Millman, Jeffrey R.; Pagliuca, Felicia Walton; DiIorio, Philip; Rezania, Alireza; Gifford, David K.; Melton, Douglas A. (National Academy of Sciences (U.S.), 2014-02)
    Human pluripotent stem cells (hPSCs) have the potential to generate any human cell type, and one widely recognized goal is to make pancreatic β cells. To this end, comparisons between differentiated cell types produced in ...
  • Jaenisch, Rudolf; Hargus, Gunnar; Cooper, Oliver; Deleidi, Michela; Levy, Adam; Lee, Kristen N.; Marlow, Elizabeth; Yow, Alyssa; Soldner, Frank; Hockemeyer, Dirk; Hallett, Penelope J.; Osborn, Teresia; Isacson, Ole (National Academy of Sciences (U.S.), 2010-08)
    Recent advances in deriving induced pluripotent stem (iPS) cells from patients offer new possibilities for biomedical research and clinical applications, as these cells could be used for autologous transplantation. We ...
  • Wan, Chen-Rei; Chung, Seok; Kamm, Roger Dale (Biomedical Engineering Society, 2011-06)
    The differentiation process of murine embryonic stem cells into cardiomyocytes was investigated with a compliant microfluidic platform which allows for versatile cell seeding arrangements, optical observation access, ...
  • Wang, Chun-Chin; Li, Feng-Chieh; Wu, Ruei-Jhih; Hovhannisyan, Vladimir; Lin, Wei-Chou; Lin, Sung-Jan; So, Peter T. C.; Dong, Chen-Yuan (Society of Photo-Optical Instrumentation Engineers, 2009-08)
    We utilize multiphoton microscopy for the label-free diagnosis of noncancerous, lung adenocarcinoma (LAC), and lung squamous cell carcinoma (SCC) tissues from humans. Our results show that the combination of second-harmonic ...
  • Stavrou, Spyridon; Crawford, Daniel; Blouch, Kristin; Browne, Edward P.; Kohli, Rahul M.; Ross, Susan R. (Public Library of Science, 2014-05)
    The apolipoprotein B editing complex 3 (A3) cytidine deaminases are among the most highly evolutionarily selected retroviral restriction factors, both in terms of gene copy number and sequence diversity. Primate genomes ...
  • Piccolo, Francesco M.; Bagci, Hakan; Brown, Karen E.; Landeira, David; Soza-Ried, Jorge; Feytout, Amelie; Mooijman, Dylan; Hajkova, Petra; Leitch, Harry G.; Tada, Takashi; Kriaucionis, Skirmantas; Dawlaty, Meelad M.; Jaenisch, Rudolf; Merkenschlager, Matthias; Fisher, Amanda G. (Elsevier, 2013-02)
    Genomic imprinting directs the allele-specific marking and expression of loci according to their parental origin. Differential DNA methylation at imprinted control regions (ICRs) is established in gametes and, although ...
  • Turco, Catherine (University of Chicago Press, 2012-09)
    The market’s tendency to organize personal spheres of life is not always unfettered, and while past studies have identified public discomfort as a bar to market expansion, this study considers a commercialization project ...
  • Lasher-Trapp, Sonia; Bansemer, Aaron; Ulanowski, Z.; Heymsfield, Andrew J.; Johnson, Alexandria V. (American Meteorological Society, 2014-06)
    The Small Ice Detector, version 2 (SID-2), High-performance Instrumented Airborne Platform for Environmental Research (HIAPER; SID-2H) was used to detect small ice particles in the early stages of ice formation in the high ...
  • Seferoglu, Hulya; Modiano, Eytan H. (Institute of Electrical and Electronics Engineers (IEEE), 2013-04)
    Backpressure routing and scheduling, with throughput-optimal operation guarantee, is a promising technique to improve throughput in wireless multi-hop networks. Although backpressure is conceptually viewed as layered, the ...
  • Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Paus, Christoph M. E. (American Physical Society, 2012-08)
    We report on a study of diffractive dijet production in p̅p collisions at √s=1.96  TeV using the CDF II detector at the Fermilab Tevatron p̅p collider. A data sample from 310  pb[superscript -1] of integrated luminosity ...
  • Bauer, Gerry P.; Gomez-Ceballos, Guillelmo; Goncharov, Maxim; Makhoul, Khaldoun; Paus, Christoph M. E. (American Physical Society, 2010-12)
    We report on a measurement of the fraction of events with a W or Z boson which are produced diffractively in p̅ p collisions at √s=1.96  [square root of s = 1.96] TeV, using data from 0.6  fb-1 [fb superscript -1] of ...
  • Biesheuvel, P. M.; Fu, Yeqing; Bazant, Martin Z. (American Physical Society, 2011-06)
    Porous electrodes instead of flat electrodes are widely used in electrochemical systems to boost storage capacities for ions and electrons, to improve the transport of mass and charge, and to enhance reaction rates. Existing ...
  • Biesheuvel, P. M.; Franco, Alejandro A.; Bazant, Martin Z. (Electrochemical Society, 2008-12)
    It is commonly assumed that electrolyte membranes in fuel cells are electrically neutral, except in unsteady situations, when the double-layer capacitance is heuristically included in equivalent circuit calculations. Indeed, ...
  • van Soestbergen, M.; Biesheuvel, P. M.; Bazant, Martin Z. (American Physical Society, 2010-02)
    We present theoretical models for the time-dependent voltage of an electrochemical cell in response to a current step, including effects of diffuse charge (or “space charge”) near the electrodes on Faradaic reaction kinetics. ...
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