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Browsing MIT Open Access Articles by Title

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  • Byers, Jeffery A.; Jamison, Timothy F. (National Academy of Sciences (U.S.), 2013-09)
    Despite the myriad of selective enzymatic reactions that occur in water, chemists have rarely capitalized on the unique properties of this medium to govern selectivity in reactions. Here we report detailed mechanistic ...
  • Faghfoor Maghrebi, Mohammad; Kantor, Yacov; Kardar, Mehran (IOP Publishing, 2011-12)
    We consider polymers attached to the tip of a cone, and the resulting force due to entropy loss on approaching a plate (or another cone). At separations shorter than the polymer radius of gyration Rg, the only relevant ...
  • Sinatra, Roberta; Szell, Michael (MDPI AG, 2014-01)
    Using mobile phone records and information theory measures, our daily lives have been recently shown to follow strict statistical regularities, and our movement patterns are, to a large extent, predictable. Here, we apply ...
  • Mistry, Karan Hemant; McGovern, Ronan Killian; Thiel, Gregory P.; Summers, Edward K.; Zubair, Syed M.; Lienhard, John H. (MDPI Publishing, 2011-09)
    Increasing global demand for fresh water is driving the development and implementation of a wide variety of seawater desalination technologies. Entropy generation analysis, and specifically, Second Law efficiency, is an ...
  • Moon, SangJun; Gurkan, Umut Atakan; Blander, Jeffrey; Fawzi, Wafaie W.; Aboud, Said; Mugusi, Ferdinand; Kuritzkes, Daniel R.; Demirci, Utkan (Public Library of Science, 2011-04)
    Background CD4+ T-lymphocyte count (CD4 count) is a standard method used to monitor HIV-infected patients during anti-retroviral therapy (ART). The World Health Organization (WHO) has pointed out or recommended that a ...
  • Pisania, Anna; Papas, Klearchos K.; Powers, Daryl E.; Rappel, Michael J.; Omer, Abdulkadir; Bonner-Weir, Susan; Weir, Gordon C.; Colton, Clark K. (Nature Publishing Group, 2010-08)
    Islet enumeration in impure preparations by conventional dithizone staining and visual counting is inaccurate and operator dependent. We examined nuclei counting for measuring the total number of cells in islet preparations, ...
  • Chiu, C. S.; Ignarra, Christina; Bugel, Leonard G.; Chen, H.; Conrad, Janet; Jones, Benjamin James Poyner; Katori, T.; Moult, Ian James (Institute of Physics Publishing, 2012-07)
    The scintillation detection systems of liquid argon time projection chambers (LArTPCs) require wavelength shifters to detect the 128 nm scintillation light produced in liquid argon. Tetraphenyl butadiene (TPB) is a fluorescent ...
  • Acemoglu, Daron; Aghion, Philippe; Bursztyn, Leonardo; Hemous, David (American Economic Association, 2012-02)
    This paper introduces endogenous and directed technical change in a growth model with environmental constraints. A unique final good is produced by combining inputs from two sectors. One of these sectors uses “dirty” ...
  • Cappellaro, Paola; Hodges, Jonathan S.; Goldstein, Garry; Jiang, Liang; Maze, Jeronimo; Sørensen, A. S.; Lukin, Mikhail D. (American Physical Society, 2012-03)
    We investigate the sensitivity of a recently proposed method for precision measurement [ Phys. Rev. Lett. 106 140502 (2011)], focusing on an implementation based on solid-state spin systems. The scheme amplifies a quantum ...
  • Goldstein, G.; Cappellaro, Paola; Maze, J. R.; Hodges, Jonathan S.; Jiang, L.; Sorensen, A. S.; Lukin, M. D. (American Physical Society, 2011-04)
    We describe a method to enhance the sensitivity of precision measurements that takes advantage of the environment of a quantum sensor to amplify the response of the sensor to weak external perturbations. An individual qubit ...
  • Rebentrost, Patrick; Mohseni, Masoud; Kassal, Ivan; Lloyd, Seth; Aspuru-Guzik, Alan (Institute of Physics Publishing, 2009-03)
    Transport phenomena at the nanoscale are of interest due to the presence of both quantum and classical behavior. In this work, we demonstrate that quantum transport efficiency can be enhanced by a dynamical interplay of ...
  • Volkov, Mikhail; Cornejo Collado, Alex; Lynch, Nancy Ann; Rus, Daniela L. (Springer Berlin / Heidelberg, 2011-11)
    This paper addresses the problem of obtaining a concise description of a physical environment for robotic exploration. We aim to determine the number of robots required to clear an environment using non-recontaminating ...
  • Ernst, Robert; Claessen, Jasper H. L.; Mueller, Britta; Sanyal, Sumana; Spooner, Eric; van der Veen, Annemarthe G.; Kirak, Oktay; Schlieker, Christian D.; Weihofen, Wilhelm A.; Ploegh, Hidde (Public Library of Science, 2011-03)
    Ubiquitin-dependent processes control much of cellular physiology. We show that expression of a highly active, Epstein-Barr virus-derived deubiquitylating enzyme (EBV-DUB) blocks proteasomal degradation of cytosolic and ...
  • Vemula, Praveen; Cruikshank, Gregory; John, George; Karp, Jeffrey Michael (Institute of Electrical and Electronics Engineers (IEEE), 2009-05)
    Utilization of enzyme catalysis as a tool to disassemble self-assembled hydrogels to control the release encapsulated drug provides an opportunity to design a wide range of enzyme-specific low-molecular-weight hydrogelators ...
  • Chryssostomidis, Chryssostomos; Karniadakis, George E.; Yang, Xiu; Venturi, Daniele; Chen, Changsheng (American Geophysical Union (AGU), 2010-12)
    Sensor placement at the extrema of empirical orthogonal functions (EOFs) is efficient and leads to accurate reconstruction of the ocean state from a limited number of measurements. In this paper, we develop important new ...
  • Cappallo, Roger J.; Corey, Brian E.; Goeke, Robert F.; Hewitt, Jacqueline N.; Kincaid, B. B.; Kratzenberg, E.; Lonsdale, Colin John; McWhirter, Stephen R.; Morgan, Edward H.; Oberoi, D.; Remillard, Ronald Alan; Rogers, Alan E. E.; Salah, J. E.; Whitney, Alan R.; Williams, Christopher Leigh (Oxford University Press, 2012-11)
    Using the final 128 antenna locations of the Murchison Widefield Array (MWA), we calculate its sensitivity to the epoch of reionization (EoR) power spectrum of redshifted 21 cm emission for a fiducial model and provide the ...
  • Farrahi, Katayoun; Emonet, Rémi; Cebrian, Manuel (Public Library of Science, 2014-05)
    Traditional contact tracing relies on knowledge of the interpersonal network of physical interactions, where contagious outbreaks propagate. However, due to privacy constraints and noisy data assimilation, this network is ...
  • Guillebaud, Julia; Mahamadou, Aboubacar; Zamanka, Halima; Katzelma, Mariama; Arzika, Ibrahim; Ibrahim, Maman L; Duchemin, Jean-Bernard; Eltahir, Elfatih A. B.; Labbo, Rabiou; Druilhe, Pierre; Fandeur, Thierry (BioMed Central Ltd., 2013-10)
    Background: Few data are available about malaria epidemiological situation in Niger. However, implementation of new strategies such as vaccination or seasonal treatment of a target population requires the knowledge of ...
  • Hackel, Benjamin J.; Neil, Jason Robert; White, Forest M.; Wittrup, Karl Dane (Oxford University Press, 2011-12)
    No single engineered protein has been shown previously to robustly downregulate epidermal growth factor receptor (EGFR), a validated cancer target. A panel of fibronectin-based domains was engineered to bind with picomolar ...
  • Octavio, Leah M.; Gedeon, Kamil S.; Maheshri, Narendra (Public Library of Science, 2009-10)
    Epigenetic switches encode their state information either locally, often via covalent modification of DNA or histones, or globally, usually in the level of a trans-regulatory factor. Here we examine how the regulation of ...
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