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Browsing MIT Open Access Articles by Title

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  • Huang, Sha, Ph. D. Massachusetts Institute of Technology; Undisz, Andreas; Diez-Silva, Monica; Bow, Hansen; Dao, Ming; Han, Jongyoon (Royal Society of Chemistry, 2012-11)
    Artesunate (ART) is widely used for the treatment of malaria, but the mechanisms of its effects on parasitized red blood cells (RBCs) are not fully understood. We investigated ART's influence on the dynamic deformability ...
  • Shwartz, A.; Prabhu, B.J.; Miller, G.; Avrachenkov, K.; Altman, E.; Menache, Ishai (Institute of Electrical and Electronics Engineers, 2009-10)
    We consider an uplink power control problem where each mobile wishes to maximize its throughput (which depends on the transmission powers of all mobiles) but has a constraint on the average power consumption. A finite ...
  • Hullin, Matthias B.; Lensch, Hendrik P. A.; Raskar, Ramesh; Seidel, Hans-Peter; Ihrke, Ivo (Wiley Blackwell, 2011-04)
    This paper deals with the challenge of physically displaying reflectance, i.e., the appearance of a surface and its variation with the observer position and the illuminating environment. This is commonly described by the ...
  • Gordon, Michael I.; Grimm, Robert; Hirzel, Martin; Soule, Robert; Amarasinghe, Saman P. (Association for Computing Machinery (ACM), 2013-06)
    Developers increasingly use streaming languages to write applications that process large volumes of data with high throughput. Unfortunately, when picking which streaming language to use, they face a difficult choice. On ...
  • Karaivanov, Alexander; Townsend, Robert (John Wiley & Sons, Inc/Econometric Society, 2014-05)
    We formulate and solve a range of dynamic models of constrained credit/insurance that allow for moral hazard and limited commitment. We compare them to full insurance and exogenously incomplete financial regimes (autarky, ...
  • Trout, Bernhardt L.; Kayser, Veysel; Chennamsetty, Naresh; Voynov, Vladimir; Helk, Bernhard; Forrer, Kurt; Zhang, Heidi; Fritsch, Cornelius; Heine, Holger (Public Library of Science, 2009-12)
    Protein-carbohydrate interactions are important for glycoprotein structure and function. Antibodies of the IgG class, with increasing significance as therapeutics, are glycosylated at a conserved site in the constant Fc ...
  • Heine, Holger; Fritsch, Cornelius; Zhang, Heidi; Forrer, Kurt; Helk, Bernhard; Voynov, Vladimir; Chennamsetty, Naresh; Kayser, Veysel; Trout, Bernhardt L. (Public Library of Science, 2009-12)
    Protein-carbohydrate interactions are important for glycoprotein structure and function. Antibodies of the IgG class, with increasing significance as therapeutics, are glycosylated at a conserved site in the constant Fc ...
  • Levy, S.; Molinari, J. F.; Radovitzky, Raul (Springer Science+Business Media, 2012-03)
    The fragmentation of a brittle plate subjected to dynamic biaxial loading is investigated via numerical simulations. The aim is to extend our understanding of the dynamic processes affecting fragment size distributions. A ...
  • McCarthy, Matthew; Waits, C. Mike; Ghodssi, Reza (Institute of Electrical and Electronics Engineers, 2009-04)
    The demonstration and characterization of a novel planar-contact encapsulated microball bearing using a radial in-flow microturbine are presented. Stable operation of the air-driven silicon microturbine is shown for over ...
  • Tian, Kehan; Arora, William J.; Takahashi, Satoshi; Hong, John; Barbastathis, George (American Physical Society, 2009-10)
    We describe a tunable slow light device based on a photonic-crystal with a mechanically adjustable coupled-resonator optical waveguide structure. The lateral energy confinement is implemented along a lattice shear defect ...
  • Day, Daniel Sindt; Park, Peter J.; Zhang, Bing; Ho, Joshua W.; Song, Lingyun; Cao, Jingjing; Christdoulou, Danos; Seidman, Jonathan G.; Crawford, Gregory E.; Pu, William T. (Cold Spring Harbor Laboratory Press, 2013-04)
    Histone modifications are now well-established mediators of transcriptional programs that distinguish cell states. However, the kinetics of histone modification and their role in mediating rapid, signal-responsive gene ...
  • Abbott, Timothy G.; Burr, Michael A.; Chan, Timothy M.; Demaine, Erik D.; Demaine, Martin L.; Hugg, John; Kane, Daniel; Langerman, Stefan; Nelson, Jelani; Rafalin, Eynat; Seyboth, Kathryn; Yeung, Vincent (Elsevier, 2009-01)
    We design efficient data structures for dynamically maintaining a ham-sandwich cut of two point sets in the plane subject to insertions and deletions of points in either set. A ham-sandwich cut is a line that simultaneously ...
  • Waite, Janelle C.; Leiner, Ingrid; Lauer, Peter; Rae, Chris S.; Barbet, Gaetan; Zheng, Huan; Portnoy, Daniel A.; Pamer, Eric G.; Dustin, Michael L. (Public Library of Science, 2011-03)
    Host defense against the intracellular pathogen Listeria monocytogenes (Lm) requires innate and adaptive immunity. Here, we directly imaged immune cell dynamics at Lm foci established by dendritic cells in the subcapsular ...
  • Hassan, Musa A.; Good, Barbara; Hanrahan, James P.; Campion, Deirdre; Sayers, Gearoid; Mulcahy, Grace; Sweeney, Torres (BioMed Central Ltd, 2011-03)
    Suffolk sheep carrying the DRB1*1101 (previously referred to as-DRB1*0203 or G2) allele have been reported to show increased resistance to natural Teladorsagia circumcincta infection compared to non-carriers. The objective ...
  • Hoffmann, Henry Christian; Sidiroglou, Stelios; Carbin, Michael James; Misailovic, Sasa; Agarwal, Anant (Association for Computing Machinery (ACM), 2011-03)
    We present PowerDial, a system for dynamically adapting application behavior to execute successfully in the face of load and power fluctuations. PowerDial transforms static configuration parameters into dynamic knobs that ...
  • Choudhury, Charisma F.; Abou-Zeid, Maya; Ben-Akiva, Moshe E. (Elsevier, 2010-01)
    Planning is an integral part of many behavioural aspects related to transportation: residential relocation, activity and travel scheduling, route choice, etc. People make plans and then select actions to execute those ...
  • Grodzinsky, Alan J.; Lee, BoBae; Han, Lin; Frank, Eliot H.; Ortiz, Christine; Grodzinsky, Alan J. (Elsevier Ltd., 2010-02)
    The success of cell-based tissue engineering approaches in restoring biological function will be facilitated by a comprehensive fundamental knowledge of the temporal evolution of the structure and properties of the newly ...
  • Toikka, Juuso; Pavan, Alessandro; Segal, Ilya (The Econometric Society, 2014-03)
    We study mechanism design in dynamic quasilinear environments where private information arrives over time and decisions are made over multiple periods. We make three contributions. First, we provide a necessary condition ...
  • Borau, Carlos; Kamm, Roger Dale (Public Library of Science, 2012-11)
    Cells modulate themselves in response to the surrounding environment like substrate elasticity, exhibiting structural reorganization driven by the contractility of cytoskeleton. The cytoskeleton is the scaffolding structure ...
  • Kim, Min-Cheol; Neal, Devin Michael; Kamm, Roger Dale; Asada, Harry (Public Library of Science, 2013-02)
    An integrative cell migration model incorporating focal adhesion (FA) dynamics, cytoskeleton and nucleus remodeling, actin motor activity, and lamellipodia protrusion is developed for predicting cell spreading and migration ...
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