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Browsing MIT Open Access Articles by Title

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  • Gupta, Piyush; Lander, Eric S.; Fillmore, Christine M.; Rudnick, Jenny A.; Caballero, Silvia; Keller, Patricia J.; Kuperwasser, Charlotte (National Academy of Sciences (U.S.), 2010-11)
    Many tumors contain heterogeneous populations of cells, only some of which exhibit increased tumorigenicity and resistance to anticancer therapies. Evidence suggests that these aggressive cancer cells, often termed “cancer ...
  • Baugher, Britton William Herb; Jarillo-Herrero, Pablo; Lemme, Max C.; Bell, David C.; Williams, James R.; Stern, Lewis A.; Marcus, Charles M. (American Chemical Society (ACS), 2009-09)
    We report on the etching of graphene devices with a helium ion beam, including in situ electrical measurement during lithography. The etching process can be used to nanostructure and electrically isolate different regions ...
  • Bousso, Raphael; Freivogel, Benjamin W.; Leichenauer, Stefan; Rosenhaus, Vladimir (American Physical Society, 2011-01)
    Present treatments of eternal inflation regulate infinities by imposing a geometric cutoff. We point out that some matter systems reach the cutoff in finite time. This implies a nonzero probability for a novel type of ...
  • Har-Peled, Sariel; Indyk, Piotr; Sidiropoulos, Anastasios (Society for Industrial and Applied Mathematics, 2013)
    A classical result in metric geometry asserts that any n-point metric admits a linear-size spanner of dilation O(log n) [PS89]. More generally, for any c > 1, any metric space admits a spanner of size O(n[superscript ...
  • Bhattacharya, Arpita; McIntosh, Kerri B.; Willis, Ian M.; Warner, Jonathan R. (Public Library of Science, 2011-08)
    It has recently become clear that the misassembly of ribosomes in eukaryotic cells can have deleterious effects that go far beyond a simple shortage of ribosomes. In this work we find that cells deficient in ribosomal ...
  • Heller, Ryan C.; Kang, Sukhyun; Lam, Wendy M.; Chen, Shuyan; Chan, Clara S.; Bell, Stephen P.; Bell, Stephen P. (Elsevier B.V., 2011-07)
    Proper eukaryotic DNA replication requires temporal separation of helicase loading from helicase activation and replisome assembly. Using an in vitro assay for eukaryotic origin-dependent replication initiation, we ...
  • Chaudhuri, Swarat; Solar Lezama, Armando (Springer-Verlag, 2012)
    We give a tutorial introduction to Euler, a system for solving difficult optimization problems involving programs.
  • Wu, Hao-Yu; Rubinstein, Michael; Shih, Eugene; Guttag, John V.; Durand, Fredo; Freeman, William T. (Association for Computing Machinery, 2012-07)
    Our goal is to reveal temporal variations in videos that are difficult or impossible to see with the naked eye and display them in an indicative manner. Our method, which we call Eulerian Video Magnification, takes a ...
  • Siemens, Mark; Li, Qing; Murnane, Margaret; Kapteyn, Henry; Yang, Ronggui; Anderson, Erik; Nelson, Keith Adam (Institute of Electrical and Electronics Engineers, 2009-08)
    We use coherent extreme ultraviolet radiation to probe surface acoustic wave propagation in nickel-on-sapphire nanostructures. We observe no acoustic dispersion over SAW wavelengths down to 200 nm, meaning the SAW propagation ...
  • Barnhart, Cynthia; Fearing, Douglas (Transportation Research Board, 2011-07)
    The collaborative decision-making (CDM) framework introduced into ground delay programs in the late 1990s is an integral component of FAA's traffic flow management (TFM) procedures. CDM allows FAA to act as a mediator when ...
  • Schmalensee, Richard (Oxford University Press, 2012-01)
    Building on a review of experience in the United States and the European Union, this article advances four main propositions concerning policies aimed at increasing electricity generation from renewable energy. First, who ...
  • Patnaik, Somani; Brunskill, Emma; Thies, William (Institute of Electrical and Electronics Engineers, 2009-04)
    While mobile phones have found broad application in reporting health, financial, and environmental data, there has been little study of the possible errors incurred during mobile data collection. This paper provides the ...
  • Do, Loi H.; Xue, Genqiang; Que, Lawrence; Lippard, Stephen J. (American Chemical Society (ACS), 2012-01)
    The composition of a (μ-oxo)diiron(III) complex coordinated by tris[(3,5-dimethyl-4-methoxy)pyridyl-2-methyl]amine (R[subscript 3]TPA) ligands was investigated. Characterization using a variety of spectroscopic methods and ...
  • Cook, Kaitlyn; Benitez, Alejandra; Fu, Casey L.; Tintle, Nathan (Frontiers Research Foundation, 2014-04)
    The new class of rare variant tests has usually been evaluated assuming perfect genotype information. In reality, rare variant genotypes may be incorrect, and so rare variant tests should be robust to imperfect data. Errors ...
  • Allen, Erik C.; Rutledge, Gregory C. (American Institute of Physics, 2009-01)
    Previously, we described a coarse-graining method for creating local density-dependent implicit solvent (DDIS) potentials that reproduce the radial distribution function (RDF) and solute excess chemical potential across a ...
  • Yuan, Yixing; Whittle, Andrew (American Society of Civil Engineers, 2011-01)
    Numerical limit analyses have been used to evaluate the stability of the 17th Street Canal I-wall levee during Hurricane Katrina. The potential formation of a water-filled gap along the canal-side soil-wall interface at ...
  • Pina, Patricia Elena; Cummings, M. L.; Donmez, Birsen (Association for Computing Machinery, 2008-01)
    Previous research has identified broad metric classes for human-automation performance to facilitate metric selection, as well as understanding and comparison of research results. However, there is still lack of an objective ...
  • Chatot, Olivier; Ishi, Carlos T.; Ishiguro, Hiroshi; Hagita, Norihiro (Institute of Electrical and Electronics Engineers, 2009-12)
    With the goal of improving human-robot speech communication, the localization of multiple sound sources in the 3D-space based on the MUSIC algorithm was implemented and evaluated in a humanoid robot embedded in real noisy ...
  • Andrews, Jason R.; Prajapati, Krishna G.; Eypper, Elizabeth; Shrestha, Poojan; Shakya, Mila; Pathak, Kamal R.; Joshi, Niva; Tiwari, Priyanka; Risal, Manisha; Koirala, Samir; Karkey, Abhilasha; Dongol, Sabina; Wen, Shawn; Maru, Duncan; Basnyat, Buddha; Baker, Stephen; Farrar, Jeremy; Ryan, Edward T.; Hohmann, Elizabeth; Arjyal, Amit; Smith, Amy (Public Library of Science, 2013-06)
    Background: In many rural areas at risk for enteric fever, there are few data on Salmonella enterica serotypes Typhi (S. Typhi) and Paratyphi (S. Paratyphi) incidence, due to limited laboratory capacity for microbiologic ...
  • Gilkey, Andrea L.; Galvan, Raquel Christine; Johnson, Aaron William; Kobrick, Ryan L.; Hoffman, Jeffrey A.; Melo, Paulo L.; Newman, Dava (American Institute of Aeronautics and Astronautics, 2011-07)
    SEXTANT is an extravehicular activity (EVA) mission planner tool developed in MATLAB, which computes the most efficient path between waypoints across a planetary surface. The traverse efficiency can be optimized around ...
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