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Browsing MIT Open Access Articles by Title

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  • Bileschi, Stanley M. (Institute of Electrical and Electronics Engineers, 2010-05)
    This work describes a fully automatic technique to calibrate a geometric mapping between lidar and video feeds on a mobile ground-based platform. This data association is a crucial first step for any multi-modal scene ...
  • Mosk-Aoyama, Damon; Roughgarden, Tim; Shah, Devavrat (Society for Industrial and Applied Mathematics (SIAM), 2010-10)
    We design and analyze a fully distributed algorithm for convex constrained optimization in networks without any consistent naming infrastructure. The algorithm produces an approximately feasible and near-optimal solution ...
  • Chen, Jing; Wang, Jiaping; Yu, Hui; Gumaste, Ashwin; Zheng, S. Q. (Institute of Electrical and Electronics Engineers, 2009-12)
    Light-trail is proposed as a candidate to carry IP traffic over wavelength division multiplexing (WDM) optical networks given its capability of accommodating multi-granularity traffic by time-division multiplexing (TDM). ...
  • Bernstein, Aaron (2009-10)
    For any fixed 1 > [epsilon] > 0 we present a fully dynamic algorithm for maintaining (2 + [epsilon])-approximate all-pairs shortest paths in undirected graphs with positive edge weights. We use a randomized (Las Vegas) ...
  • Chen, Xiangyu; Akinwande, Deji; Lee, Kyeong-Jae; Close, Gael F.; Yasuda, Shinichi; Paul, Bipul C.; Fujita, Shinobu; Kong, Jing; Wong, H. -S. Philip (Institute of Electrical and Electronics Engineers (IEEE), 2010-09)
    Carbon-based nanomaterials such as metallic single-walled carbon nanotubes, multiwalled carbon nanotubes (MWCNTs), and graphene have been considered as some of the most promising candidates for future interconnect technology ...
  • Ramadass, Yogesh Kumar; Fayed, Ayman A.; Chandrakasan, Anantha P. (Institute of Electrical and Electronics Engineers, 2010-12)
    Implementing efficient and cost-effective power regulation schemes for battery-powered mixed-signal SoCs is a key focus in integrated circuit design. This paper presents a fully-integrated switched-capacitor DC-DC converter ...
  • Sun, Jian; Giuliano, David Michael; Devarajan, Siddharth; Lu, Jian-Qiang; Chow, T. Paul; Gutmann, Ronald J. (Institute of Electrical and Electronics Engineers, 2009-02)
    A fully monolithic interleaved buck dc-dc point-of-load (PoL) converter has been designed and fabricated in a 0.18-mm SiGe BiCMOS process. Target application of the design is 3-D power delivery for future microprocessors, ...
  • Hutchinson, Ian H.; Patacchini, Leonardo (Institute of Electrical and Electronics Engineers, 2009-08)
    We carry out 3D particle-in-cell simulations accounting for the full ion distribution function, Boltzmann electrons, and the self-consistent potential profiles in the neighborhood of a sphere in a flowing magnetized plasma. ...
  • Sheng, Morgan Hwa-Tze; Knapska, Ewelina; Macias, Matylda; Mikosz, Marta; Nowak, Aleksandra; Owczarek, Dorota; Wawrzyniak, Marcin; Pieprzyk, Marcelina; Cymerman, Iwona A.; Werka, Tomasz; Maren, Stephen; Jaworski, Jacek; Kaczmarek, Leszek (National Academy of Sciences (U.S.), 2012-10)
    The memory of fear extinction is context dependent: fear that is suppressed in one context readily renews in another. Understanding of the underlying neuronal circuits is, therefore, of considerable clinical relevance for ...
  • Bajaj, Vikram S.; Mak-Jurkauskas, Melody L.; Belenky, Marina; Herzfeld, Judith; Griffin, Robert Guy (National Academy of Sciences, 2009-06)
    Observation and structural studies of reaction intermediates of proteins are challenging because of the mixtures of states usually present at low concentrations. Here, we use a 250 GHz gyrotron (cyclotron resonance maser) ...
  • Walker, Graham C.; Modia, Sheetal R.; Camachoa, Diogo M.; Kohanski, Michael A.; Collins, James J. (Proceedings of the National Academy of Sciences (PNAS), 2011-08)
    Small RNAs (sRNAs) are important components of posttranscriptional regulation. These molecules are prevalent in bacterial and eukaryotic organisms, and involved in a variety of responses to environmental stresses. The ...
  • Dunfield, Derek; Podgorski, Kaspar; Haas, Kurt (Public Library of Science, 2012-01)
    Sensory experience drives dramatic structural and functional plasticity in developing neurons. However, for single-neuron plasticity to optimally improve whole-network encoding of sensory information, changes must be ...
  • Doshi, Vishal; Shah, Devavrat; Medard, Muriel; Effros, Michelle (Institute of Electrical and Electronics Engineers, 2010-08)
    Motivated by applications to sensor networks and privacy preserving databases, we consider the problem of functional compression. The objective is to separately compress possibly correlated discrete sources such that an ...
  • Ang, Wee Han; Lippard, Stephen J. (Royal Society of Chemistry, 2009-09)
    Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.
  • Agrawal, Amit; Min, Dal-Hee; Singh, Neetu; Zhu, Haihao; Birjiniuk, Alona; Von Maltzahn, Geoffrey; Harris, Todd J.; Xing, Deyin; Woolfenden, Stephen D.; Sharp, Phillip A.; Charest, Alain; Bhatia, Sangeeta N. (American Chemical Society, 2009-09)
    Small interfering RNAs (siRNAs) mediate cleavage of specific, complementary mRNA sequences and thus regulate gene expression. Not surprisingly, their use for treatment of diseases that are rooted in aberrant gene expression, ...
  • DeKelver, Russell C.; Choi, Vivian M.; Moehle, Erica A.; Paschon, David E.; Hockemeyer, Dirk; Meijsing, Sebastiaan H.; Sancak, Yasemin; Cui, Xiaoxia; Steine, Eveline J.; Miller, Jeffrey C.; Tam, Phillip; Bartsevich, Victor V.; Meng, Xiangdong; Rupniewski, Igor; Gopalan, Sunita M.; Sun, Helena C.; Pitz, Kathleen J.; Rock, Jeremy M.; Zhang, Lei; Davis, Gregory D.; Rebar, Edward J.; Cheeseman, Iain McPherson; Yamamoto, Keith R.; Sabatini, David M.; Jaenisch, Rudolf; Gregory, Philip D.; Urnov, Fyodor D. (Cold Spring Harbor Laboratory Press, 2010-05)
    Isogenic settings are routine in model organisms, yet remain elusive for genetic experiments on human cells. We describe the use of designed zinc finger nucleases (ZFNs) for efficient transgenesis without drug selection ...
  • Possemato, Richard; Marks, Kevin M.; Shaul, Yoav D.; Pacold, Michael E.; Kim, Dohoon; Birsoy, Kivanc; Sethumadhavan, Shalini; Woo, Hin-Koon; Jang, Hyun G.; Jha, Abhishek K.; Chen, Walter W.; Barrett, Francesca G.; Stransky, Nicolas; Tsun, Zhi-Yang; Cowley, Glenn S.; Barretina, Jordi; Kalaany, Nada Y.; Hsu, Peggy P.; Ottina, Kathleen; Chan, Albert M.; Yuan, Bingbing B.; Garraway, Levi A.; Root, David E.; Mino-Kenudson, Mari; Brachtel, Elena F.; Driggers, Edward M.; Sabatini, David M. (Nature Publishing Group, 2011-08)
    Cancer cells adapt their metabolic processes to drive macromolecular biosynthesis for rapid cell growth and proliferation[superscript 1, 2]. RNA interference (RNAi)-based loss-of-function screening has proven powerful for ...
  • Langs, Georg; Golland, Polina; Tie, Yanmei; Rigolo, Laura; Golby, Alexandra J. (2010-12)
    Matching functional brain regions across individuals is a challenging task, largely due to the variability in their location and extent. It is particularly difficult, but highly relevant, for patients with pathologies such ...
  • Swager, Timothy M.; Sydlik, Stefanie Arlene (Wiley Blackwell, 2012-11)
    Current research in materials has devoted much attention to graphene, with a considerable amount of the chemical manipulation going through the oxidized state of the material, known as graphene oxide (GO). In this report, ...
  • Gupta, Piyush; Rudnick, Jenny A.; Arendt, Lisa M.; Klebba, Ina; Hinds, John W.; Iyer, Vandana; Naber, Stephen P.; Kuperwasser, Charlotte (Public Library of Science, 2011-09)
    Fibroblasts are important in orchestrating various functions necessary for maintaining normal tissue homeostasis as well as promoting malignant tumor growth. Significant evidence indicates that fibroblasts are functionally ...
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