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Browsing MIT Open Access Articles by Title

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  • Kim, Min-Cheol; Neal, Devin Michael; Kamm, Roger Dale; Asada, Harry (Public Library of Science, 2013-02)
    An integrative cell migration model incorporating focal adhesion (FA) dynamics, cytoskeleton and nucleus remodeling, actin motor activity, and lamellipodia protrusion is developed for predicting cell spreading and migration ...
  • Smith, Stephen L.; Bullo, Francesco; Pavone, Marco; Frazzoli, Emilio (Institute of Electrical and Electronics Engineers, 2009-07)
    In this paper we study a dynamic vehicle routing problem in which there are multiple vehicles and multiple classes of demands. Demands of each class arrive in the environment randomly over time and require a random amount ...
  • Vasquez, Claudia G.; Tworoger, Michael B.; Martin, Adam C. (Rockefeller University Press, 2014-08)
    Apical constriction is a cell shape change that promotes epithelial bending. Activation of nonmuscle myosin II (Myo-II) by kinases such as Rho-associated kinase (Rok) is important to generate contractile force during apical ...
  • Bierlaire, Michel; Osorio Pizano, Carolina; Flotterod, Gunnar (Elsevier, 2011-05)
    We present a dynamic network loading model that yields queue length distributions, accounts for spillbacks, and maintains a differentiable mapping from the dynamic demand on the dynamic queue lengths. The model also captures ...
  • Debelouchina, Galia Tzvetanova; Bayro, Marvin J.; van der Wel, Patrick C. A.; Caporini, Marc A.; Barnes, Alexander; Rosay, Melanie; Maas, Werner E.; Griffin, Robert Guy (Royal Society of Chemistry, The, 2010-05)
    Dynamic nuclear polarization (DNP) utilizes the inherently larger polarization of electrons to enhance the sensitivity of conventional solid-state NMR experiments at low temperature. Recent advances in instrumentation ...
  • Gunther, William R.; Michaelis, Vladimir K.; Caporini, Marc A.; Griffin, Robert Guy; Roman, Yuriy; Gunther, William R (American Chemical Society (ACS), 2014-04)
    The catalytic activity of tin-containing zeolites, such as Sn-Beta, is critically dependent on the successful incorporation of the tin metal center into the zeolite framework. However, synchrotron-based techniques or ...
  • Akbey, Umit; Franks, W. Trent; Linden, Arne; Lange, Sascha; Griffin, Robert Guy; van Rossum, Barth-Jan; Oschkinat, Harmut (Wiley-Blackwell Pubishers, 2010-08)
    For D's a jolly good fellow: Deuteration of proteins significantly increases the signal enhancements observed in dynamic nuclear polarization (DNP) magic-angle spinning (MAS) NMR experiments. In 13C CP-MAS spectra an ...
  • Michaelis, Vladimir K.; Markhasin, Evgeny; Daviso, Eugenio; Herzfeld, Judith; Griffin, Robert Guy (American Chemical Society (ACS), 2012-07)
    Oxygen-17-detected DNP NMR of a water/glycerol glass enabled an 80-fold enhancement of signal intensity at 82 K, using the biradical TOTAPOL. The >6000-fold savings in acquisition time enable [superscript 17]O–[superscript ...
  • Ravera, Enrico; Michaelis, Vladimir K.; Rosa, Camilla; Luchinat, Claudio; Bertini, Ivano; Griffin, Robert Guy; Corzilius, Bjorn (American Chemical Society (ACS), 2013-01)
    Using the 480 kDa iron-storage protein complex, apoferritin (ApoF), as an example, we demonstrate that sizable dynamic nuclear polarization (DNP) enhancements can be obtained on sedimented protein samples. In sedimented ...
  • Michaelis, Vladimir K.; Smith, Albert A.; Corzilius, Bjorn; Griffin, Robert Guy (American Chemical Society (ACS), 2013-11)
    Dynamic nuclear polarization of [superscript 17]O was studied using four different polarizing agents: the biradical TOTAPOL and the monoradicals trityl and SA-BDPA, as well as a mixture of the latter two. Field profiles, ...
  • Andreas, Loren B.; Barnes, Alexander B.; Chou, James J.; Caporini, Marc; Rosay, Melanie; Corzilius, Bjorn; Miller, Eric Alexander; Griffin, Robert Guy (American Chemical Society (ACS), 2013-03)
    We demonstrate the use of dynamic nuclear polarization (DNP) to elucidate ligand binding to a membrane protein using dipolar recoupling magic angle spinning (MAS) NMR. In particular, we detect drug binding in the proton ...
  • Matsuki, Yoh; Maly, Thorsten; Ouari, Olivier; Karoui, Hakim; Le Moigne, Francois; Rizzato, Egon; Lyubenova, Sevdalina; Herzfeld, Judith; Prisner, Thomas; Tordo, Paul; Griffin, Robert Guy (John Wiley & Sons, Inc., 2009-06)
    A new polarizing agent with superior performance in dynamic nuclear polarization experiments is introduced, and utilizes two TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) moieties connected through a rigid spiro tether (see ...
  • Kiesewetter, Matthew K.; Smith, Albert A.; Corzilius, Bjorn; Griffin, Robert Guy; Swager, Timothy Manning (American Chemical Society (ACS), 2012-02)
    A new biradical polarizing agent, bTbtk-py, for dynamic nuclear polarization (DNP) experiments in aqueous media is reported. The synthesis is discussed in light of the requirements of the optimum, theoretical, biradical ...
  • Menache, Ishai; Ozdaglar, Asuman E.; Srikant, R.; Acemoglu, Daron (2009-07)
    We study dynamic models of online-advertising auctions in the Internet: advertisers compete for space on a web page over multiple time periods, and the web page displays ads in differentiated slots based on their bids and ...
  • Pham, Hubert; Paluska, Justin Mazzola; Saif, Umar; Stawarz, Christopher; Terman, Christopher J.; Ward, Stephen A. (Institute of Electrical and Electronics Engineers, 2009-05)
    We present a middleware platform for assembling pervasive applications that demand fault-tolerance and adaptivity in distributed, dynamic environments. Unlike typical adaptive middleware approaches, in which sophisticated ...
  • Walcott-Bryant, Aisha; Kaess, Michael; Johannsson, Hordur; Leonard, John Joseph (Institute of Electrical and Electronics Engineers (IEEE), 2013-05-16)
    Maintaining a map of an environment that changes over time is a critical challenge in the development of persistently autonomous mobile robots. Many previous approaches to mapping assume a static world. In this work we ...
  • Bahr, Alexander; Leonard, John Joseph; Martinoli, Alcherio (Institute of Electrical and Electronics Engineers (IEEE), 2012-10)
    Autonomous Underwater Vehicles (AUVs) are used for an ever increasing range of applications due to the maturing of the technology. Due to the absence of the GPS signal underwater, the correct estimation of its position is ...
  • Menache, Ishai; Orda, Ariel; Naor, Joseph (Seffi); Lewin-Eytan, Liane; Buchbinder, Niv (Institute of Electrical and Electronics Engineers, 2009-06)
    A major problem in wireless networks is coping with limited resources, such as bandwidth and energy. These issues become a major algorithmic challenge in view of the dynamic nature of the wireless domain. We consider in ...
  • Roozbehani, Mardavij; Dahleh, Munther A.; Mitter, Sanjoy K. (Institute of Electrical and Electronics Engineers, 2010-10)
    The paper proposes a mechanism for real-time pricing of electricity in smart power grids, with price stability as the primary concern. In previous publications the authors argued that relaying the real-time wholesale market ...
  • Lobel, Ruben; Perakis, Georgia (Airline Group of the International Federation of Operational Research Societies, 2011-10)
    In this paper we develop an approach to dynamic pricing that combines ideas from data-driven and robust optimization to address the uncertain and dynamic aspects of the problem. In our setting, a firm off ers multiple ...
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