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Browsing MIT Open Access Articles by Title

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  • Samson, Leona D.; Begley, Thomas J.; Lahue, Robert S.; Daee, Danielle L.; Fry, Rebecca C.; Erlich, Rachel L. (Public Library of Science, 2008-11)
  • Pickrell, Joseph K.; Patterson, Nick; Loh, Po-Ru; Lipson, Mark; Berger, Bonnie; Stoneking, Mark; Pakendorf, Brigitte; Reich, David (National Academy of Sciences (U.S.), 2014-02)
    The history of southern Africa involved interactions between indigenous hunter–gatherers and a range of populations that moved into the region. Here we use genome-wide genetic data to show that there are at least two ...
  • Williams, Bret R.; Amon, Angelika B. (American Association for Cancer Research, 2009-07)
    Aneuploidy is a characteristic of cancer, with greater than 90% of all solid tumors in humans carrying an aberrant karyotype. Yet, whether or how this condition contributes to tumorigenesis is not understood. Here we ...
  • Sheltzer, Jason Meyer; Blank, Heidi Marie; Pfau, Sarah Jeanne; Tange, Yoshie; George, Benson M.; Humpton, Timothy J.; Brito, Ilana L.; Hiraoka, Yasushi; Niwa, Osami; Amon, Angelika B. (American Association for the Advancement of Science, 2011-08)
    Aneuploidy decreases cellular fitness, yet it is also associated with cancer, a disease of enhanced proliferative capacity. To investigate one mechanism by which aneuploidy could contribute to tumorigenesis, we examined ...
  • Thorburn, Rebecca Ruth; Gonzalez, Christian; Brar, Gloria A.; Christen, Stefan; Carlile, Thomas M.; Ingolia, Nicholas T.; Sauer, Uwe; Weissman, Jonathan S.; Amon, Angelika B. (American Society for Cell Biology, 2013-03)
    Aneuploidy, a chromosome content that is not a multiple of the haploid karyotype, is associated with reduced fitness in all organisms analyzed to date. In budding yeast aneuploidy causes cell proliferation defects, with ...
  • Oromendia, Ana Belen; Amon, Angelika B. (Company of Biologists, 2014-01)
    It has long been appreciated that aneuploidy – in which cells possess a karyotype that is not a multiple of the haploid complement – has a substantial impact on human health, but its effects at the subcellular level have ...
  • Ploegh, Hidde; Maehr, Rene; Greer, Paul L.; Hanayama, Rikinari; Bloodgood, Brenda L.; Mardinly, Alan R.; Lipton, David M.; Flavell, Steven W.; Kim, Tae-Kyung; Griffith, Eric C.; Waldon, Zachary; Chowdhury, Shoaib; Worley, Paul F.; Steen, Judith; Greenberg, Michael E. (Elsevier, 2010-03)
    Angelman Syndrome is a debilitating neurological disorder caused by mutation of the E3 ubiquitin ligase Ube3A, a gene whose mutation has also recently been associated with autism spectrum disorders (ASDs). The function of ...
  • Chauhan, Vikash P.; Liu, Hao; Lacorre, Delphine A.; Jain, Saloni R.; Kozin, Sergey V.; Stylianopoulos, Triantafyllos; Mousa, Ahmed S.; Han, Xiaoxing; Adstamongkonkul, Pichet; Huang, Peigen; Bawendi, Moungi G.; Boucher, Yves; Jain, Rakesh K.; Martin, John Daniel; Popovic, Zoran (Nature Publishing Group, 2013-10)
    Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan ...
  • Chan, M. K.; Li, Y.; Xia, D. D.; Yu, G.; Zhao, X.; Lee, W. S.; Meevasana, W.; Devereaux, T. P.; Greven, M.; Shen, Z.-X.; Vishik, Inna; Barisic, N. (American Physical Society, 2014-05)
    HgBa[subscript 2]CuO[subscript 4+δ]. (Hg1201) has been shown to be a model cuprate for scattering, optical, and transport experiments, but angle-resolved photoemission spectroscopy (ARPES) data are still lacking owing to ...
  • Counts, Ian Thomas Hunt; Ilten, Philip James; Williams, Michael (Springer-Verlag, 2014-05)
    The angular distributions of the rare decays B [superscript +] → K [superscript +] μ [superscript +] μ [superscript −] and B[superscript 0] → K[0 over S]μ[superscript +]μ[superscript −] are studied with data corresponding ...
  • Dooley, Katherine L.; Barsotti, Lisa; Adhikari, Rana X.; Fricke, Tobin T.; Frolov, Valera; Kawabe, Keita; Evans, Matthew J.; Fritschel, Peter K.; Smith-Lefebvre, Nicolas (Optical Society of America, 2013-11)
    We describe the angular sensing and control (ASC) of 4 km detectors of the Laser Interferometer Gravitational-Wave Observatory (LIGO). Enhanced LIGO, the culmination of the first generation LIGO detectors, operated between ...
  • Simo, I. Ruiz; Albertus, C.; Amaro, J. E.; Barbaro, M. B.; Caballero, J. A.; Donnelly, T. William (American Physical Society, 2014-09)
    The angular distribution of the phase space arising in two-particle emission reactions induced by electrons and neutrinos is computed in the laboratory (Lab) system by boosting the isotropic distribution in the center of ...
  • Zhao, M.; Yamamoto, R. K.; Taylor, Frank E.; Spitznagel, M.; Sciolla, Gabriella; Koeneke, K.; Cowan, Ray Franklin; Dujmic, Denis; Fisher, Peter H. (American Physical Society, 2009-02)
    We use a sample of 384×10[superscript 6] BB[over-bar] events collected with the BABAR detector at the PEP-II e+e- collider to study angular distributions in the rare decays B-->K*ℓ+ℓ-, where ℓ+ℓ- is either e+e- or μ+μ-. ...
  • Liu, Hong; Ooguri, Hirosi; Stoica, Bogdan (American Physical Society, 2014-05)
    We generalize our holographic derivation of spontaneous angular momentum generation in 2 + 1 dimensions in several directions. We consider cases when a parity-violating perturbation responsible for the angular momentum ...
  • Hamam, Rafif E.; Celanovic, Ivan; Soljacic, Marin (American Physical Society, 2011-03)
    We present detailed numerical simulations of a class of material systems that strongly discriminate light based primarily on the angle of incidence, over a broad range of frequencies, and independent of the polarization. ...
  • Peng, Chunte; Jones, Kevin C.; Tokmakoff, Andrei (American Chemical Society (ACS), 2011-08)
    Polarization-dependent two-dimensional infrared (2D IR) spectra of the purine and pyrimadine base vibrations of five nucleotide monophosphates (NMPs) were acquired in D[subscript 2]O at neutral pH in the frequency range ...
  • Fox, James G. (Springer Science+Business Media/Humana Press, 2012)
    Animal models of microbial diseases in humans are an essential component for determining fulfillment of Koch’s postulates and determining how the organism causes disease, host response(s), disease prevention, and treatment. ...
  • Condry, Ian (Sage Publications, 2009-03)
    This article examines ethnographically the production of anime (Japanese animated films and TV shows) by focusing on how professional animators use characters and dramatic premises to organize their collaborative creativity. ...
  • Shen, Chen; Xu, Jun; Jing, Yun; Fang, Nicholas Xuanlai (American Physical Society, 2014-11)
    In this paper, we investigate a type of anisotropic, acoustic complementary metamaterial (CMM) and its application in restoring acoustic fields distorted by aberrating layers. The proposed quasi two-dimensional (2D), ...
  • Wang, Lifeng; Song, Juha; Ortiz, Christine; Boyce, Mary Cunningham (Cambridge University Press/Materials Research Society, 2009-12)
    Biological materials have developed hierarchical and heterogeneous material microstructures and nanostructures to provide protection against environmental threats that, in turn, provide bioinspired clues to improve human ...
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