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Browsing MIT Open Access Articles by Title

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  • Algorithms for Designing Pop-Up Cards 
    Abel, Zachary Ryan; Demaine, Erik D.; Demaine, Martin L.; Eisenstat, Sarah Charmian; Lubiw, Anna; Schulz, Andre; Souvaine, Diane L.; Viglietta, Giovanni; Winslow, Andrew (Schloss Dagstuhl Publishing, 2013-02)
    We prove that every simple polygon can be made as a (2D) pop-up card/book that opens to any desired angle between 0 and 360°. More precisely, given a simple polygon attached to the two walls of the open pop-up, our ...
  • Algorithms for scheduling task-based applications onto heterogeneous many-core architectures 
    Kinsy, Michel A.; Devadas, Srinivas (Institute of Electrical and Electronics Engineers (IEEE), 2014-09)
    In this paper we present an Integer Linear Programming (ILP) formulation and two non-iterative heuristics for scheduling a task-based application onto a heterogeneous many-core architecture. Our ILP formulation is able to ...
  • Algorithms for solving rubik's cubes 
    Demaine, Erik D.; Demaine, Martin L.; Eisenstat, Sarah Charmian; Lubiw, Anna; Winslow, Andrew (Springer Berlin / Heidelberg, 2011-08)
    The Rubik’s Cube is perhaps the world’s most famous and iconic puzzle, well-known to have a rich underlying mathematical structure (group theory). In this paper, we show that the Rubik’s Cube also has a rich underlying ...
  • Algorithms for Symmetric Submodular Function Minimization under Hereditary Constraints and Generalizations 
    Goemans, Michel X.; Soto, Jose A. (Society for Industrial and Applied Mathematics, 2013-06)
    We present an efficient algorithm to find nonempty minimizers of a symmetric submodular function f over any family of sets I closed under inclusion. Our algorithm makes O(n[superscript 3]) oracle calls to f and I, where n ...
  • Algorithms for the analysis of ensemble neural spiking activity using simultaneous-event multivariate point-process models 
    Ba, Demba; Temereanca, Simona; Brown, Emery N. (Frontiers Research Foundation, 2014-02)
    Understanding how ensembles of neurons represent and transmit information in the patterns of their joint spiking activity is a fundamental question in computational neuroscience. At present, analyses of spiking activity ...
  • Algorithm to determine the percolation largest component in interconnected networks 
    Herrmann, Hans J.; Schneider, Christian Michael; Araujo, Nuno (American Physical Society, 2013-04)
    Interconnected networks have been shown to be much more vulnerable to random and targeted failures than isolated ones, raising several interesting questions regarding the identification and mitigation of their risk. The ...
  • Alien Maps of an Ocean-Bearing World 
    Cowan, Nicolas B.; Agol, Eric; Meadows, Victoria S.; Robinson, Tyler; Livengood, Timothy A.; Deming, Drake; Lisse, Carey M.; A'Hearn, Michael F.; Wellnitz, Dennis D.; Seager, Sara; Charbonneau, David (IOP Publishing, 2009-07)
    When Earth-mass extrasolar planets first become detectable, one challenge will be to determine which of these worlds harbor liquid water, a widely used criterion for habitability. Some of the first observations of these ...
  • Aligned carbon nanotube array stiffness from stochastic three-dimensional morphology 
    Stein, Itai Y.; Wardle, Brian L.; Lewis, Diana Jean (Royal Society of Chemistry, 2015-11)
    The landmark theoretical properties of low dimensional materials have driven more than a decade of research on carbon nanotubes (CNTs) and related nanostructures. While studies on isolated CNTs report behavior that aligns ...
  • Aligned Carbon Nanotube Reinforcement of Aerospace Carbon Fiber Composites: Substructural Strength Evaluation for Aerostructure Applications 
    Guzman de Villoria, Roberto; Ydrefors, L.; Hallander, P.; Ishiguro, Kyoko; Nordin, P.; Wardle, Brian L. (American Institute of Aeronautics and Astronautics, 2012-04)
    Vertically aligned carbon nanotubes (VACNTs) are placed between all plies in an aerospace carbon fiber reinforced plastic laminate (unidirectional plies, [(0/90/±45)2]s) to reinforce the interlaminar region in the ...
  • Aligned Sub-10-nm Block Copolymer Patterns Templated by Post Arrays 
    Chang, Jae-Byum; Son, Jeong Gon; Hannon, Adam F.; Alexander-Katz, Alfredo; Ross, Caroline A.; Berggren, Karl K. (American Chemical Society, 2012-03)
    Self-assembly of block copolymer films can generate useful periodic nanopatterns, but the self-assembly needs to be templated to impose long-range order and to control pattern registration with other substrate features. ...
  • Aligning Perspectives and Methods for Value-Driven Design 
    Ross, Adam Michael; O'Neill, Michael Gregory; Hastings, Daniel E.; Rhodes, Donna H. (American Institute of Aeronautics and Astronautics, 2010-08)
    Recent years have seen a push to use explicit consideration of “value” in order to drive design. This paper conveys the need to explicitly align perspectives on “value” with the method used to quantify “value.” Various ...
  • Alignment-Free Phylogenetic Reconstruction 
    Daskalakis, Constantinos; Roch, Sebastien (Springer Berlin / Heidelberg, 2010-05)
    We introduce the first polynomial-time phylogenetic reconstruction algorithm under a model of sequence evolution allowing insertions and deletions (or indels). Given appropriate assumptions, our algorithm requires sequence ...
  • Alignment-free phylogenetic reconstruction: Sample complexity via a branching process analysis 
    Roch, Sebastien; Daskalakis, Konstantinos (Institute of Mathematical Statistics, 2013-04)
    We present an efficient phylogenetic reconstruction algorithm allowing insertions and deletions which provably achieves a sequence-length requirement (or sample complexity) growing polynomially in the number of taxa. Our ...
  • Alignment of the stellar spin with the orbits of a three-planet system 
    Sanchis Ojeda, Roberto; Fabrycky, Daniel C.; Winn, Joshua Nathan; Barclay, Thomas; Clarke, Bruce D.; Ford, Eric B.; Fortney, Jonathan J.; Geary, John C.; Holman, Matthew J.; Howard, Andrew W.; Jenkins, Jon M.; Koch, David; Lissauer, Jack J.; Marcy, Geoffrey W.; Mullally, Fergal; Ragozzine, Darin; Seader, Shawn E.; Still, Martin; Thompson, Susan E. (Nature Publishing Group, 2012-07)
    The Sun’s equator and the planets’ orbital planes are nearly aligned, which is presumably a consequence of their formation from a single spinning gaseous disk. For exoplanetary systems this well-aligned configuration is ...
  • The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond 
    Fedeles, Bogdan I.; Singh, Vipender; Delaney, James C.; Li, Deyu; Essigmann, John M. (American Society for Biochemistry and Molecular Biology (ASBMB), 2015-07)
    The AlkB family of Fe(II)- and α-ketoglutarate-dependent dioxygenases is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleobases by oxidative dealkylation. The prototypical and ...
  • Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage 
    Endres, Lauren; Begley, Ulrike; Clark, Ryan; Gu, Chen; Dziergowska, Agnieszka; Małkiewicz, Andrzej; Melendez, J. Andres; Dedon, Peter C.; Begley, Thomas J. (Public Library of Science, 2015-07)
    Environmental and metabolic sources of reactive oxygen species (ROS) can damage DNA, proteins and lipids to promote disease. Regulation of gene expression can prevent this damage and can include increased transcription, ...
  • Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB) 
    van Loon, Barbara; Samson, Leona D. (Elsevier, 2013-01)
    Due to a harsh environment mitochondrial genomes accumulate high levels of DNA damage, in particular oxidation, hydrolytic deamination, and alkylation adducts. While repair of alkylated bases in nuclear DNA has been explored ...
  • Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides 
    Lu, Zhe; Fu, Gregory C. (Wiley Blackwell, 2010-08)
    No such thing as a problem substrate! In a reaction designed specifically for the title substrates C-C coupling with alkyl boranes occurred in good yield at room temperature with commercially available catalyst components ...
  • Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins 
    Bugni, J. M.; Meira, Lisiane B.; Samson, Leona D. (Nature Publishing Group, 2008-11)
    O[superscript 6]-methylguanine DNA methyltransferase (MGMT) suppresses mutations and cell death that result from alkylation damage. MGMT expression is lost by epigenetic silencing in a variety of human cancers including ...
  • Alkylation of Dinitrogen in [(HIPTNCH[subscript 2]CH[subscript 2])[subscript 3]N]Mo Complexes (HIPT = 3,5-(2,4,6-i-Pr[subscript 3]C[subscript 6]H[subscript 2])[subscript 2]C[subscript 6]H[subscript 3]) 
    Kupfer, Thomas; Schrock, Richard Royce (American Chemical Society (ACS), 2009-08)
    In this paper we explore the ethylation of dinitrogen (employing [Et[subscript 3]O][BAr[f over 4]]; Ar[superscript f] = 3,5-(CF[subscript 3])[subscript 2]C[subscript 6]H[subscript 3]) in [HIPTN[subscript 3]N]Mo (Mo) complexes ...
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