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Browsing MIT Open Access Articles by Title

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  • Anatomy-Based Algorithms for Detecting Oral Cancer Using Reflectance and Fluorescence Spectroscopy 
    McGee, Sasha; Mardirossian, Vartan; Elackattu, Alphi; Mirkovic, Jelena; Pistey, Robert; Gallagher, George; Kabani, Sadru; Yu, Chung-Chieh; Wang, Zimmern; Badizadegan, Kamran; Grillone, Gregory; Feld, Michael S. (Annals Publishing Company, 2009-11)
    OBJECTIVES: We used reflectance and fluorescence spectroscopy to noninvasively and quantitatively distinguish benign from dysplastic/malignant oral lesions. We designed diagnostic algorithms to account for differences in ...
  • Anc1, a Protein Associated with Multiple Transcription Complexes, Is Involved in Postreplication Repair Pathway in S-cerevisiae 
    Samson, Leona D.; Begley, Thomas J.; Lahue, Robert S.; Daee, Danielle L.; Fry, Rebecca C.; Erlich, Rachel L. (Public Library of Science, 2008-11)
  • Ancient west Eurasian ancestry in southern and eastern Africa 
    Pickrell, Joseph K.; Patterson, Nick; Loh, Po-Ru; Lipson, Mark; Berger, Bonnie; Stoneking, Mark; Pakendorf, Brigitte; Reich, David (National Academy of Sciences (U.S.), 2014-02)
    The history of southern Africa involved interactions between indigenous hunter–gatherers and a range of populations that moved into the region. Here we use genome-wide genetic data to show that there are at least two ...
  • ANDROMEDA (M31) OPTICAL AND INFRARED DISK SURVEY. I. INSIGHTS IN WIDE-FIELD NEAR-IR SURFACE PHOTOMETRY 
    Sick, Jonathan; Cuillandre, Jean-Charles; de Jong, Roelof; Tully, R. Brent; McDonald, Michael A.; Courteau, Stephane (IOP Publishing, 2014-04)
    We present wide-field near-infrared J and K[subscript s] images of the Andromeda Galaxy (M31) taken with WIRCam at the Canada-France-Hawaii Telescope as part of the Andromeda Optical and Infrared Disk Survey. This data set ...
  • Aneuploidy: Cancer's Fatal Flaw? 
    Williams, Bret R.; Amon, Angelika B. (American Association for Cancer Research, 2009-07)
    Aneuploidy is a characteristic of cancer, with greater than 90% of all solid tumors in humans carrying an aberrant karyotype. Yet, whether or how this condition contributes to tumorigenesis is not understood. Here we ...
  • Aneuploidy Drives Genomic Instability in Yeast 
    Sheltzer, Jason Meyer; Blank, Heidi Marie; Pfau, Sarah Jeanne; Tange, Yoshie; George, Benson M.; Humpton, Timothy J.; Brito, Ilana L.; Hiraoka, Yasushi; Niwa, Osami; Amon, Angelika B. (American Association for the Advancement of Science, 2011-08)
    Aneuploidy decreases cellular fitness, yet it is also associated with cancer, a disease of enhanced proliferative capacity. To investigate one mechanism by which aneuploidy could contribute to tumorigenesis, we examined ...
  • Aneuploid yeast strains exhibit defects in cell growth and passage through START 
    Thorburn, Rebecca Ruth; Gonzalez, Christian; Brar, Gloria A.; Christen, Stefan; Carlile, Thomas M.; Ingolia, Nicholas T.; Sauer, Uwe; Weissman, Jonathan S.; Amon, Angelika B. (American Society for Cell Biology, 2013-03)
    Aneuploidy, a chromosome content that is not a multiple of the haploid karyotype, is associated with reduced fitness in all organisms analyzed to date. In budding yeast aneuploidy causes cell proliferation defects, with ...
  • Aneuploidy: implications for protein homeostasis and disease 
    Oromendia, Ana Belen; Amon, Angelika B. (Company of Biologists, 2014-01)
    It has long been appreciated that aneuploidy – in which cells possess a karyotype that is not a multiple of the haploid complement – has a substantial impact on human health, but its effects at the subcellular level have ...
  • The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc 
    Ploegh, Hidde; Maehr, Rene; Greer, Paul L.; Hanayama, Rikinari; Bloodgood, Brenda L.; Mardinly, Alan R.; Lipton, David M.; Flavell, Steven W.; Kim, Tae-Kyung; Griffith, Eric C.; Waldon, Zachary; Chowdhury, Shoaib; Worley, Paul F.; Steen, Judith; Greenberg, Michael E. (Elsevier, 2010-03)
    Angelman Syndrome is a debilitating neurological disorder caused by mutation of the E3 ubiquitin ligase Ube3A, a gene whose mutation has also recently been associated with autism spectrum disorders (ASDs). The function of ...
  • Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels 
    Chauhan, Vikash P.; Liu, Hao; Lacorre, Delphine A.; Jain, Saloni R.; Kozin, Sergey V.; Stylianopoulos, Triantafyllos; Mousa, Ahmed S.; Han, Xiaoxing; Adstamongkonkul, Pichet; Huang, Peigen; Bawendi, Moungi G.; Boucher, Yves; Jain, Rakesh K.; Martin, John Daniel; Popovic, Zoran (Nature Publishing Group, 2013-10)
    Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan ...
  • Angle-resolved photoemission spectroscopy study of HgBa[subscript 2]CuO[subscript 4+δ] 
    Chan, M. K.; Li, Y.; Xia, D. D.; Yu, G.; Zhao, X.; Lee, W. S.; Meevasana, W.; Devereaux, T. P.; Greven, M.; Shen, Z.-X.; Vishik, Inna; Barisic, N. (American Physical Society, 2014-05)
    HgBa[subscript 2]CuO[subscript 4+δ]. (Hg1201) has been shown to be a model cuprate for scattering, optical, and transport experiments, but angle-resolved photoemission spectroscopy (ARPES) data are still lacking owing to ...
  • Angular analysis of charged and neutral B → Kμ[superscript +]μ[superscript −] decays 
    Counts, Ian Thomas Hunt; Ilten, Philip James; Williams, Michael (Springer-Verlag, 2014-05)
    The angular distributions of the rare decays B [superscript +] → K [superscript +] μ [superscript +] μ [superscript −] and B[superscript 0] → K[0 over S]μ[superscript +]μ[superscript −] are studied with data corresponding ...
  • Angular control of optical cavities in a radiation-pressure-dominated regime: the Enhanced LIGO case 
    Dooley, Katherine L.; Barsotti, Lisa; Adhikari, Rana X.; Fricke, Tobin T.; Frolov, Valera; Kawabe, Keita; Evans, Matthew J.; Fritschel, Peter K.; Smith-Lefebvre, Nicolas (Optical Society of America, 2013-11)
    We describe the angular sensing and control (ASC) of 4 km detectors of the Laser Interferometer Gravitational-Wave Observatory (LIGO). Enhanced LIGO, the culmination of the first generation LIGO detectors, operated between ...
  • Angular distribution in two-particle emission induced by neutrinos and electrons 
    Simo, I. Ruiz; Albertus, C.; Amaro, J. E.; Barbaro, M. B.; Caballero, J. A.; Donnelly, T. William (American Physical Society, 2014-09)
    The angular distribution of the phase space arising in two-particle emission reactions induced by electrons and neutrinos is computed in the laboratory (Lab) system by boosting the isotropic distribution in the center of ...
  • Angular distributions in the decay B-->K[superscript *]l[superscript +]l[superscript -] 
    Zhao, M.; Yamamoto, R. K.; Taylor, Frank E.; Spitznagel, M.; Sciolla, Gabriella; Koeneke, K.; Cowan, Ray Franklin; Dujmic, Denis; Fisher, Peter H. (American Physical Society, 2009-02)
    We use a sample of 384×10[superscript 6] BB[over-bar] events collected with the BABAR detector at the PEP-II e+e- collider to study angular distributions in the rare decays B-->K*ℓ+ℓ-, where ℓ+ℓ- is either e+e- or μ+μ-. ...
  • Angular momentum generation by parity violation 
    Liu, Hong; Ooguri, Hirosi; Stoica, Bogdan (American Physical Society, 2014-05)
    We generalize our holographic derivation of spontaneous angular momentum generation in 2 + 1 dimensions in several directions. We consider cases when a parity-violating perturbation responsible for the angular momentum ...
  • Angular photonic band gap 
    Hamam, Rafif E.; Celanovic, Ivan; Soljacic, Marin (American Physical Society, 2011-03)
    We present detailed numerical simulations of a class of material systems that strongly discriminate light based primarily on the angle of incidence, over a broad range of frequencies, and independent of the polarization. ...
  • Anharmonic Vibrational Modes of Nucleic Acid Bases Revealed by 2D IR Spectroscopy 
    Peng, Chunte; Jones, Kevin C.; Tokmakoff, Andrei (American Chemical Society (ACS), 2011-08)
    Polarization-dependent two-dimensional infrared (2D IR) spectra of the purine and pyrimadine base vibrations of five nucleotide monophosphates (NMPs) were acquired in D[subscript 2]O at neutral pH in the frequency range ...
  • Animal Models of Helicobacter-Induced Disease: Methods to Successfully Infect the Mouse [chapter] 
    Fox, James G. (Springer Science+Business Media/Humana Press, 2012)
    Animal models of microbial diseases in humans are an essential component for determining fulfillment of Koch’s postulates and determining how the organism causes disease, host response(s), disease prevention, and treatment. ...
  • Anime Creativity: Characters and Premises in the Quest for Cool Japan 
    Condry, Ian (Sage Publications, 2009-03)
    This article examines ethnographically the production of anime (Japanese animated films and TV shows) by focusing on how professional animators use characters and dramatic premises to organize their collaborative creativity. ...
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