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Browsing MIT Open Access Articles by Title

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  • Shim, Keun Sup; Lis, Mieszko; Cho, Myong Hyon; Devadas, Srinivas; Lebedev, Ilia A. (Institute of Electrical and Electronics Engineers (IEEE), 2013-10)
    As transistor technology continues to scale, the architecture community has experienced exponential growth in design complexity and significantly increasing implementation and verification costs. Moreover, Moore's law has ...
  • Maiti, Panchanan; Lomakin, Aleksey; Benedek, George B.; Bitan, Gal (Wiley Blackwell, 2010-06)
    An important component of the pathologic process underlying Alzheimer’s disease is oxidative stress. Met[superscript 35] in amyloid β-protein (Aβ) is prone to participating in redox reactions promoting oxidative stress, ...
  • Limaye, Ajay B. S.; Aharonson, Oded; Perron, J. Taylor (American Geophysical Union (AGU), 2012-06)
    The Mars polar layered deposits (PLD) likely hold an extensive record of recent climate during a period of high-amplitude orbit and obliquity cycles. Previous work has detected limited evidence for orbital signatures within ...
  • Mitschang, Arik W.; Schulz, Norbert S.; Huenemoerder, David P.; Nichols, Joy S.; Testa, Paola; Huenemoerder, David P. (Institute of Physics/American Astronomical Society, 2011-06)
    We investigate X-ray emission properties of the peculiar X-ray source θ[superscript 2] Ori A in the Orion Trapezium region using more than 500 ks of HETGS spectral data in the quiescent state. The amount of exposure provides ...
  • Sharp, Phillip A.; Boutz, Paul; Bhutkar, Arjun (AJ) (Cold Spring Harbor Laboratory Press, 2015-01)
    Deep sequencing of embryonic stem cell RNA revealed many specific internal introns that are significantly more abundant than the other introns within polyadenylated transcripts; we classified these as “detained” introns ...
  • Carter, Joshua Adam; Winn, Joshua Nathan (Institute of Physics, 2010-05)
    Knowledge of an exoplanet's oblateness and obliquity would give clues about its formation and internal structure. In principle, a light curve of a transiting planet bears information about the planet's shape, but previous ...
  • Peherstorfer, Benjamin; Willcox, Karen E (Elsevier, 2015-06)
    We consider the task of dynamic capability estimation for an unmanned aerial vehicle, which is needed to provide the vehicle with the ability to dynamically and autonomously sense, plan, and act in real time. Our dynamic ...
  • Carbin, Michael James; Misailovic, Sasa; Kling, Michael W.; Rinard, Martin C. (Springer Berlin / Heidelberg, 2011-07)
    Infinite loops can make applications unresponsive. Potential problems include lost work or output, denied access to application functionality, and a lack of responses to urgent events. We present Jolt, a novel system for ...
  • Tonzetich, Zachary J.; McQuade, Lindsey E.; Lippard, Stephen J. (American Chemical Society (ACS), 2010-07)
    We are pursuing a dual strategy for investigating the chemistry of nitric oxide as a biological signaling agent. In one approach, metal-based fluorescent sensors for the detection of NO in living cells are evaluated, and ...
  • Fish, Vincent L.; Doeleman, Sheperd Samuel; Broderick, Avery E.; Loeb, Abraham; Rogers, Alan E. E. (IOP Publishing, 2009-11)
    Sagittarius A* is the source of near infrared, X-ray, radio, and (sub)millimeter emission associated with the supermassive black hole at the Galactic Center. In the submillimeter regime, Sgr A* exhibits time-variable linear ...
  • Mocci, Andrea; Sangiorgio, Mario (Springer Vienna, 2012-09)
    Modern software systems are composed of several services which may be developed and maintained by third parties and thus they can change independently and without notice during the system’s runtime execution. In such ...
  • Qi, Yang; Fu, Liang (American Physical Society, 2015-03)
    In quantum spin liquid states, the fractionalized spinon excitations can carry fractional crystal symmetry quantum numbers, and this symmetry fractionalization distinguishes different symmetry-enriched spin liquid states ...
  • Saracco, Fabio; Gabrielli, Andrea; Squartini, Tiziano; Di Clemente, Riccardo (Nature Publishing Group, 2016-07)
    Since 2007, several contributions have tried to identify early-warning signals of the financial crisis. However, the vast majority of analyses has focused on financial systems and little theoretical work has been done on ...
  • Sweet, Andrew; Venkataraman, Archana; Stufflebeam, Steven M.; Liu, Hesheng; Tanaka, Naoro; Madsen, Joseph R.; Golland, Polina (Springer-Verlag Berlin Heidelberg, 2013)
    We present a method to detect epileptic regions based on functional connectivity differences between individual epilepsy patients and a healthy population. Our model assumes that the global functional characteristics of ...
  • Doeleman, Sheperd Samuel; Fish, Vincent L.; Broderick, Avery E.; Loeb, Abraham; Rogers, Alan E. E. (Institute of Physics/American Astronomical Society, 2009-04)
    The super-massive black hole candidate, Sagittarius A*, exhibits variability from radio to X-ray wavelengths on timescales that correspond to <10 Schwarzschild radii. We survey the potential of millimeter wavelength very ...
  • Bansal, Mukul S.; Banay, Guy; Gogarten, J. Peter; Shamir, Ron (Mary Ann Liebert, Inc., 2011-09)
    In a horizontal gene transfer (HGT) event, a gene is transferred between two species that do not have an ancestor-descendant relationship. Typically, no more than a few genes are horizontally transferred between any two ...
  • Cheow, Lih Feng; Sarkar, Aniruddh; Kolitz, Sarah; Han, Jongyoon; Lauffenburger, Douglas A. (American Chemical Society (ACS), 2014-07)
    Electrokinetic preconcentration coupled with mobility shift assays can give rise to very high detection sensitivities. We describe a microfluidic device that utilizes this principle to detect cellular kinase activities by ...
  • Wyble, Brad; Potter, Mary C; Hagmann, Carl; McCourt, Emily Sarah (Springer US, 2013-12)
    The visual system is exquisitely adapted to the task of extracting conceptual information from visual input with every new eye fixation, three or four times a second. Here we assess the minimum viewing time needed for ...
  • Wang, Feng; Kaplan, Jess L.; Gold, Benjamin D.; Bhasin, Manoj K.; Ward, Naomi L.; Kellermayer, Richard; Kirschner, Barbara S.; Heyman, Melvin B.; Dowd, Scot E.; Cox, Stephen B.; Dogan, Haluk; Steven, Blaire; Ferry, George D.; Cohen, Stanley A.; Baldassano, Robert N.; Moran, Christopher J.; Garnett, Elizabeth A.; Drake, Lauren; Otu, Hasan H.; Mirny, Leonid A.; Libermann, Towia A.; Winter, Harland S.; Korolev, Kirill S. (Elsevier, 2016-01)
    The relationship between the host and its microbiota is challenging to understand because both microbial communities and their environments are highly variable. We have developed a set of techniques based on population ...
  • Savoie, Troy B.; Frey, Daniel (Springer-Verlag, 2011-11)
    This paper presents the results of an experiment with human subjects investigating their ability to discover a mistake in a model used for engineering design. For the purpose of this study, a known mistake was intentionally ...
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