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Browsing MIT Open Access Articles by Title

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  • Shapiro, Irina M.; Cheng, Albert W.; Flytzanis, Nicholas C.; Balsamo, Michele; Condeelis, John S.; Oktay, Maja H.; Burge, Christopher B.; Gertler, Frank (Public Library of Science, 2011-08)
    Epithelial-mesenchymal transition (EMT), a mechanism important for embryonic development, plays a critical role during malignant transformation. While much is known about transcriptional regulation of EMT, alternative ...
  • Shapira, Ofer; Abouraddy, Ayman F.; Hu, Qichao; Shemuly, Dana; Joannopoulos, John D.; Fink, Yoel (Optical Society of America, 2010-06)
    The ability to precisely and selectively excite superpositions of specific fiber eigenmodes allows one in principle to control the three dimensional field distribution along the length of a fiber. Here we demonstrate the ...
  • Helmer, Karl G.; Ambite, Jose Luis; Ames, Joseph; Ananthakrishnan, Rachana; Burns, Gully; Chervenak, Ann L.; Foster, Ian; Liming, Lee; Keator, David; Macciardi, Fabio; Madduri, Ravi; Navarro, John-Paul; Potkin, Steven; Rosen, Bruce R.; Ruffins, Seth; Schuler, Robert; Turner, Jessica A.; Toga, Arthur; Williams, Christina; Kesselman, Carl; Biomedical Informatics Research Network (BMJ Publishing Group on behalf of the American Medical Informatics Association, 2011-04)
    Objective As biomedical technology becomes increasingly sophisticated, researchers can probe ever more subtle effects with the added requirement that the investigation of small effects often requires the acquisition of ...
  • Chuah, Meng Yee; Kim, Sangbae (Institute of Electrical and Electronics Engineers (IEEE), 2014-03)
    This paper presents a new force sensor design approach that maps the local sampling of pressure inside a composite polymeric footpad to forces in three axes, designed for running robots. Conventional multiaxis force sensors ...
  • Yeng, YiXiang; Ghebrebrhan, Michael; Bermel, Peter A.; Chan, Walker R.; Joannopoulos, John D.; Soljacic, Marin; Celanovic, Ivan (National Academy of Sciences, 2012-02)
    The nascent field of high-temperature nanophotonics could potentially enable many important solid-state energy conversion applications, such as thermophotovoltaic energy generation, selective solar absorption, and selective ...
  • de Montjoye, Yves-Alexandre; Kendall, Jake; Kerry, Cameron (Brookings Center for Technology Innovation, 2014-11)
    The prevalence of mobile communication in the developing world is ever increasing, with now 89 active subscriptions per 100 inhabitants. With this access comes the potential for unprecedented insights into individuals and ...
  • Yeng, Yi Xiang; Lenert, Andrej; Rinnerbauer, Veronika; Celanovic, Ivan; Wang, Evelyn N.; Kim, Sang-Gook; Chou, Jeffrey Brian; Lee, Yoon Kyung; Soljacic, Marin; Fang, Nicholas Xuanlai (Wiley Blackwell, 2014-09)
    A metallic dielectric photonic crystal with solar broadband, omni-directional, and tunable selective absorption with high temperature stable (1000 °C, 24 hrs) properties is fabricated on a 6” silicon wafer. The broadband ...
  • Hardison, James; DeLong, Kimberly K.; Harward, V. Judson; del Alamo, Jesus A.; Shroff, R.; Oyabode, O. (American Society of Civil Engineers, 2010-03)
    The MIT iLab Project is dedicated to the goal of increasing laboratory experimentation opportunities for engineering students worldwide. Since its inception in 1998, the project has furthered this goal through the development ...
  • Bravo-Abad, Jorge; Joannopoulos, John D.; Soljacic, Marin (National Academy of Sciences (U.S.), 2012-06)
    Many of graphene’s unique electronic properties emerge from its Dirac-like electronic energy spectrum. Similarly, it is expected that a nanophotonic system featuring Dirac dispersion (two conical bands touching at a single ...
  • Aisopos, Konstantinos; Chen, Chia-Hsin; Peh, Li-Shiuan (Association for Computing Machinery (ACM), 2011-06)
    Process Variation (PV) is increasingly threatening the reliability of Networks-on-Chips. Thus, various resilient router designs have been recently proposed and evaluated. However, these evaluations assume random fault ...
  • Santambrogio, Marco Domenico; Hoffmann, Henry Christian; Eastep, Jonathan Michael; Agarwal, Anant (Institute of Electrical and Electronics Engineers, 2010-06)
    Self-aware computer systems will be capable of adapting their behavior and resources thousands of times a second to automatically find the best way to accomplish a given goal despite changing environmental conditions and ...
  • Zhu, Shaolin; Niljianskul, Nootaree; Buchwald, Stephen Leffler (American Chemical Society (ACS), 2013-10)
    A highly enantio- and regioselective copper-catalyzed hydroamination reaction of alkenes has been developed using diethoxymethylsilane and esters of hydroxylamines. The process tolerates a wide variety of substituted ...
  • Lou, Sha; Fu, Gregory C. (American Chemical Society, 2010-03)
    A new family of organometallic compounds, organozirconium reagents, are shown to serve as suitable partners in cross-coupling reactions of (activated) secondary alkyl electrophiles. Thus, the first catalytic method for ...
  • Fujiwara, Yuji; Sun, Jianwei; Fu, Gregory C. (Royal Society of Chemistry, The, 2011-08)
    An effective phosphine-catalyzed method was developed for the enantioselective addition of aryl thiols to the γ position of allenoates, thereby providing ready access to aryl alkyl sulfides in very good ee. The array of ...
  • Zhu, Rong; Buchwald, Stephen Leffler (Wiley Blackwell, 2013-10)
    Something radical: An efficient enantioselective oxytrifluoromethylation of alkenes has been developed using a copper catalyst system. Mechanistic studies are consistent with a metal-catalyzed redox radical addition mechanism ...
  • Lee, Sarah Yunmi; Neufeind, Stefan; Fu, Gregory C. (American Chemical Society (ACS), 2014-06)
    The catalytic asymmetric synthesis of alkyl fluorides, particularly α-fluorocarbonyl compounds, has been the focus of substantial effort in recent years. While significant progress has been described in the formation of ...
  • Shen, Xiaoqiang; Jones, Gavin O.; Watson, Donald A.; Bhayana, Brijesh; Buchwald, Stephen Leffler (American Chemical Society (ACS), 2010-07)
    We report efficient syntheses of axially chiral biaryl amides in yields ranging from 80−92%, and with enantioselectivity in the range 88−94% ee employing an asymmetric Suzuki−Miyaura process with Pd(OAc)[subscript 2] and ...
  • Movassaghi, Mohammad; Piersanti, Giovanni; Piizzi, Grazia; Siegel, Dustin Scott (American Chemical Society, 2009-11)
    We report our full account of the enantioselective total synthesis of (−)-acylfulvene (1) and (−)-irofulven (2), which features metathesis reactions for the rapid assembly of the molecular framework of these antitumor ...
  • Kwiatkowski, Adam V.; Rubinson, Douglas A.; Dent, Erik W.; Edward van Veen, J.; Leslie, Jonathan D.; Zhang, Jiangyang; Mebane, Leslie M.; Philippar, Ulrike; Pinheiro, Elaine M.; Burds, Aurora A.; Bronson, Roderick T.; Mori, Susumu; Gertler, Frank; Fassler, Reinhard (Elsevier, 2007-11)
    Mammalian cortical development involves neuronal migration and neuritogenesis; this latter process forms the structural precursors to axons and dendrites. Elucidating the pathways that regulate the cytoskeleton to drive ...
  • Goh, Keow Lin; Cai, Li; Cepko, Constance L.; Gertler, Frank (Elsevier, 2002-04)
    Development of the multilayered cerebral cortex involves extensive regulated migration of neurons arising from the deeper germinative layers of the mammalian brain [1]. The anatomy and formation of the cortical layers has ...
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