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Browsing MIT Open Access Articles by Title

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  • Tzafriri, A. R.; Levin, A. D.; Edelman, Elazer R. (Wiley Blackwell, 2009-03)
    Background:  Local drug delivery has transformed medicine, yet it remains unclear how drug efficacy depends on physicochemical properties and delivery kinetics. Most therapies seek to prolong release, yet recent studies ...
  • Kindler, Kolja; Khalili, Arzhang; Stocker, Roman (National Academy of Sciences (U.S.), 2010-12)
    Downward carbon flux in the ocean is largely governed by particle settling. Most marine particles settle at low Reynolds numbers and are highly porous, yet the fluid dynamics of this regime have remained unexplored. We ...
  • Wedeen, Van J.; Sosnovik, David; Reese, Timothy G.; Dai, Guangping; Wang, Ruopeng (BioMed Central, 2009-11)
    Histological studies have shown that the myocardium consists of an array of crossing helical fiber tracts. Changes in myocardial fiber architecture occur in ischemic heart disease and heart failure, and can be imaged ...
  • Lizana, L.; Ambjornsson, T. (American Physical Society, 2009-11)
    We solve a nonequilibrium statistical-mechanics problem exactly, namely, the single-file dynamics of N hard-core interacting particles (the particles cannot pass each other) of size Δ diffusing in a one-dimensional system ...
  • Acemoglu, Daron; Ozdaglar, Asuman E.; Yildiz, Ercan (Institute of Electrical and Electronics Engineers (IEEE), 2011-12)
    While social networks do affect diffusion of innovations, the exact nature of these effects are far from clear, and, in many cases, there exist conflicting hypotheses among researchers. In this paper, we focus on the linear ...
  • Acemoglu, Daron; Ozdaglar, Asuman E.; Scaglione, Anna; Yildez, Mehmet Ercan (2011-05)
    In this paper, we are interested in modeling diffusion of innovations on social networks. We focus on a scenario where innovation emerges at a small number of nodes in the society, and each individual needs certain ...
  • Stylianopoulos, Triantafyllos; Poh, Ming-Zher; Insin, Numpon; Bawendi, Moungi G.; Fukumura, Dai; Munn, Lance L.; Jain, Rakesh K. (Elsevier, 2010-09)
    Diffusive transport of macromolecules and nanoparticles in charged fibrous media is of interest in many biological applications, including drug delivery and separation processes. Experimental findings have shown that ...
  • Silbey, Robert J.; Barkai, E. (American Physical Society, 2010-04)
    We study the diffusion of tagged hard-core interacting Brownian point particles under the influence of an external force field in one dimension. Using the Jepsen line we map this many-particle problem onto a single particle ...
  • Park, Mansoo; Alexander, Kathleen C; Schuh, Christopher A (Elsevier, 2014-05)
    The solute diffusion of tungsten at low concentrations in chromium has been investigated both by experiments and computational methods. From finite-source diffusion experiments measured with an Electron Probe Micro Analyzer ...
  • Pfefferbaum, Adolf; Adalsteinsson, Elfar; Rohlfing, Torsten; Sullivan, Edith V. (Elsevier, 2008-05)
    Diffusion tensor imaging (DTI) of the brain has become a mainstay in the study of normal aging of white matter, and only recently has attention turned to the use of DTI to examine aging effects in gray matter structures. ...
  • Deng, Chuang; Schuh, Christopher A. (American Physical Society, 2011-12)
    An adapted simulation method is used to systematically study grain boundary motion at velocities and driving forces across more than five orders of magnitude. This analysis reveals that grain boundary migration can occur ...
  • Lu, Timothy K.; Roquet, Nathaniel Bernard (Wiley Blackwell, 2014-05)
    Biotechnology offers the promise of valuable chemical production via microbial processing of renewable and inexpensive substrates. Thus far, static metabolic engineering strategies have enabled this field to advance ...
  • Cohen, Jamie; Penney, Dana L.; Davis, Randall; Libon, David J.; Swenson, Rodney A.; Ajilore, Olusola; Kumar, Anand; Lamar, Melissa (Cambridge University Press, 2014-09)
    Psychomotor slowing has been documented in depression. The digital Clock Drawing Test (dCDT) provides: (i) a novel technique to assess both cognitive and motor aspects of psychomotor speed within the same task and (ii) the ...
  • Spielberg, Nathan A.; Klein, John; Oxman, Neri; Keating, Steven John (Springer-Verlag, 2014)
    We introduce a novel large-scale Digital Construction Platform (DCP) for on-site sensing, analysis, and fabrication. The DCP is an in-progress research project consisting of a compound robotic arm system comprised of a ...
  • Girardin, Fabien; Blat, Josep; Calabrese, Francesco; Dal Fiore, Filippo; Ratti, Carlo (Institute of Electrical and Electronics Engineers, 2008-10)
    Novel methods and tools are being developed to explore the significance of the new types of user-related spatiotemporal data. This approach helps uncover the presence and movements of tourists from cell phone network data ...
  • Luengo-Oroz, Miguel A.; Duloquin, Louise; Savy, Thierry; Rizzi, Barbara; Desnoulez, Sophie; Kergosien, Yannick L.; Bourgine, Paul; Castro Gonzalez, Carlos; Doursat, Rene; Peyrieras, Nadine; Santos, Andres; Ledesma-Carbayo, Maria J. (Public Library of Science, 2014-06)
    A gene expression atlas is an essential resource to quantify and understand the multiscale processes of embryogenesis in time and space. The automated reconstruction of a prototypic 4D atlas for vertebrate early embryos, ...
  • Onaga, Lisa; Shell, Hanna Rose (Muse - Johns Hopkins University Press, 2016-01)
    On 11 March 2011, a giant earthquake and tsunami off the coast of Japan triggered the Fukushima Daiichi nuclear disaster. Failure of the plant’s heating and cooling system and an inability to properly stabilize the reactors ...
  • Ratti, Carlo; Morello, Eugenio (Pion Ltd., 2009-04)
    New techniques to measure 2D and 3D visibility over urban spaces are presented in this paper. The concept of the isovist, that is, the visible space from a vantage point, could help in providing a quantifiable basis for ...
  • Havasi, Catherine; Pustejovsky, James; Speer, Robert H.; Lieberman, Henry A. (Institute of Electrical and Electronics Engineers, 2009-07)
    Understanding the world we live in requires access to a large amount of background knowledge: the commonsense knowledge that most people have and most computer systems don't. Many of the limitations of artificial intelligence ...
  • Bohorquez, Jose L.; Yip, Marcus; Chandrakasan, Anantha P.; Dawson, Joel L. (Institute of Electrical and Electronics Engineers, 2010-06)
    Acompact, low-power, digitally-assisted sensor interface for biomedical applications is presented. It exploits oversampling and digital design to reduce system area and power, while making the system more robust to ...
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