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Browsing MIT Open Access Articles by Title

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  • Piner, Edwin L.; Chung, Jinwook; Saadat, Omair Irfan; Palacios, Tomas (Institute of Electrical and Electronics Engineers, 2009-11)
    This letter describes a gate-first AlGaN/GaN high-electron mobility transistor (HEMT) with a W/high-k dielectric gate stack. In this new fabrication technology, the gate stack is deposited before the ohmic contacts, and ...
  • Guo, Shiping; Tirado, Jose M.; Gao, Xiang; Saadat, Omair Irfan; Chung, Jae W.; Palacios, Tomas (Institute of Electrical and Electronics Engineers, 2009-08)
    We studied submicrometer (L[subscript G] = 0.15-0.25 à ¿m) gate-recessed InAlN/AlN/GaN high-electron mobility transistors (HEMTs) on SiC substrates with 25-nm Al[subscript 2]O[subscript 3] passivation. The combination of ...
  • Hull, Chris; Zwiebach, Barton (IOP Publishing, 2009-09)
    We investigate the symmetry algebra of the recently proposed field theory on a doubled torus that describes closed string modes on a torus with both momentum and winding. The gauge parameters are constrained fields on the ...
  • Chetverikov, Denis; Kato, Kengo; Chernozhukov, Victor V. (Institute of Mathematical Statistics, 2013-12)
    We derive a Gaussian approximation result for the maximum of a sum of high-dimensional random vectors. Specifically, we establish conditions under which the distribution of the maximum is approximated by that of the maximum ...
  • Choi, Myung Jin; Chandrasekaran, Venkat; Willsky, Alan S. (Institute of Electrical and Electronics Engineers, 2010-02)
    In this paper, we consider the problem of learning Gaussian multiresolution (MR) models in which data are only available at the finest scale, and the coarser, hidden variables serve to capture long-distance dependencies. ...
  • Weedbrook, Christian; Pirandola, Stefano; Garcia-Patron Sanchez, Raul; Cerf, Nicolas J.; Ralph, Timothy C.; Shapiro, Jeffrey H.; Lloyd, Seth (American Physical Society, 2012-05)
    The science of quantum information has arisen over the last two decades centered on the manipulation of individual quanta of information, known as quantum bits or qubits. Quantum computers, quantum cryptography, and quantum ...
  • Mendenhall, Eric M.; Koche, Richard Patrick; Truong, Thanh; Zhou, Vicky W.; Issac, Biju; Chi, Andrew S.; Ku, Manching; Bernstein, Bradley E. (Public Library of Science, 2010-12)
    Polycomb proteins are epigenetic regulators that localize to developmental loci in the early embryo where they mediate lineage-specific gene repression. In Drosophila, these repressors are recruited to sequence elements ...
  • Searle, S.; Frankish, A.; Bignell, A.; Aken, B.; Derrien, T.; Diekhans, M.; Harte, R.; Howald, C.; Kokocinski, F.; Lin, M.; Tress, M.; Van Baren, M.; Barnes, I.; Hunt, T.; Carvalho-Silva, D.; Davidson, C.; Donaldson, S.; Gilbert, J.; Kay, M.; Lloyd, D.; Loveland, J.; Mudge, J.; Snow, C.; Vamathevan, J.; Wilming, L.; Brent, M.; Gerstein, M.; Guigo, R.; Kellis, Manolis; Reymond, A.; Zadissa, A.; Valencia, A.; Harrow, J.; Hubbard, T. (BioMed Central Ltd., 2010-10)
    The GENCODE consortium is a sub group of the ENCODE consortium. Its aim is to provide complete annotation of genes in the human genome including protein-coding loci, non-coding loci and pseudogenes, based on experimental ...
  • Lin, Michael; Kellis, Manolis (Cold Spring Harbor Laboratory Press, 2012-09)
    The GENCODE Consortium aims to identify all gene features in the human genome using a combination of computational analysis, manual annotation, and experimental validation. Since the first public release of this annotation ...
  • Ellison, Glenn; Swanson, Ashley Terese (American Economic Association, 2010)
    This paper uses a new data source, American Mathematics Competitions, to examine the gender gap among high school students at very high achievement levels. The data bring out several new facts. There is a large gender gap ...
  • Fernandez, Roberto; Friedrich, Colette (Regents of the University of California, 2011-03)
    We document gender sorting of candidates into gender-typed jobs at the point of initial application to a company. At this step of the hiring process, the firm has implemented a policy whereby organizational screeners’ ...
  • Regev, Aviv; Wapinski, Ilan; Pfiffner, Jenna; French, Courtney; Socha, Amanda; Thompson, Dawn Anne (National Academy of Sciences (U.S.), 2010-03)
    Coexpression of genes within a functional module can be conserved at great evolutionary distances, whereas the associated regulatory mechanisms can substantially diverge. For example, ribosomal protein (RP) genes are tightly ...
  • Cheung, Vincent Chi-Kwan; DeBoer, Caroline; Hanson, Elizabeth; Tunesi, Marta; D'Onofrio, Mara; Arisi, Ivan; Brandi, Rossella; Cattaneo, Antonino; Goosens, Ki Ann (Public Library of Science, 2013-04)
    The primary motor cortex (M1) supports motor skill learning, yet little is known about the genes that contribute to motor cortical plasticity. Such knowledge could identify candidate molecules whose targeting might enable ...
  • Berger, Bonnie; Palmer, Nathan Patrick; Schmid, Patrick Raphael; Kohane, Isaac (BioMed Central Ltd, 2012-08)
    Abstract Background Understanding the fundamental mechanisms of tumorigenesis remains one of the most pressing problems in modern biology. To this end, stem-like cells with tumor-initiating potential have become a central ...
  • Regev, Aviv; Immunological Genome Consortium (Nature Publishing Group, 2012-09)
    We assessed gene expression in tissue macrophages from various mouse organs. The diversity in gene expression among different populations of macrophages was considerable. Only a few hundred mRNA transcripts were selectively ...
  • Boissonneault, Katie; Henningsen, Brooks M; Bates, Stephen S; Robertson, Deborah L; Milton, Sean; Pelletier, Jerry; Hogan, Deborah A; Housman, David E; Housman, David E. (Biomed Central Ltd., 2013-11)
    Background: Pseudo-nitzschia multiseries Hasle (Hasle) (Ps-n) is distinctive among the ecologically important marine diatoms because it produces the neurotoxin domoic acid. Although the biology of Ps-n has been investigated ...
  • Spidlen, Josef; Barsky, Aaron; Breuer, Karin; Carr, Peter; Nazaire, Marc-Danie; Hill, Barbara A; Qian, Yu; Liefeld, Ted; Reich, Michael; Wilkinson, Peter; Scheuermann, Richard H; Sekaly, Rafick-Pierre; Brinkman, Ryan R; Hill, Barbara; Mesirov, Jill P. (BioMed Central Ltd, 2013-07)
    Background: Traditional flow cytometry data analysis is largely based on interactive and time consuming analysis of series two dimensional representations of up to 20 dimensional data. Recent technological advances have ...
  • Adida, Ben; Kohane, Isaac (BioMed Central Ltd, 2006-04)
    Background: Patient genomic data are rapidly becoming part of clinical decision making. Within a few years, full genome expression profiling and genotyping will be affordable enough to perform on every individual. The ...
  • Brown, Emery N.; Purdon, Patrick Lee; Van Dort, Christa (Annual Reviews, 2011-07)
    Placing a patient in a state of general anesthesia is crucial for safely and humanely performing most surgical and many nonsurgical procedures. How anesthetic drugs create the state of general anesthesia is considered a ...
  • Schiff, Nicholas D.; Brown, Emery N.; Lydic, Emily K. (New England Journal of Medicine, 2010-12)
    In the United States, nearly 60,000 patients per day receive general anesthesia for surgery.1 General anesthesia is a drug-induced, reversible condition that includes specific behavioral and physiological traits — ...
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