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Browsing MIT Open Access Articles by Title

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  • Van Dyke, Aaron R.; Jamison, Timothy F. (Wiley Blackwell, 2009-05)
    Extension ladder: The successful application of epoxide-opening strategies towards the synthesis of ladder-type polyethers is contingent upon further elaboration of the product. By employing two different functionalized ...
  • Shulman, J. M.; Parrado, A.; Lindhagen-Persson, M.; Reiman, E. M.; Evans, D. A.; Bennett, D. A.; Olofsson, A.; DeJager, P. L.; Tanzi, R. E.; Caldwell, K. A.; Caldwell, G. A.; Lindquist, S.; Treusch, Sebastian; Hamamichi, Shusei; Goodman, Jessica L.; Matlack, Kent E. S.; Chung, Chee Yeun; Baru, Valeriya; Valastyan, Julie Suzanne; Han, Haesun; Lindquist, Susan; Bevis, Brooke J. (American Association for the Advancement of Science (AAAS), 2011-10)
    Aβ (beta-amyloid peptide) is an important contributor to Alzheimer’s disease (AD). We modeled Aβ toxicity in yeast by directing the peptide to the secretory pathway. A genome-wide screen for toxicity modifiers identified ...
  • Lang, Matthew J.; Appleyard, David C. (Institute of Electrical and Electronics Engineers, 2009-08)
    We present a parts perspective using biological components to form complex systems and discuss: connectivity, network formation, and motility. Challenges associated with characterization and assembly are discussed relative ...
  • Caterson, Stephanie A.; Fox, Sharon E.; Tobias, Adam M.; Lee, Bernard T. (Public Library of Science, 2012-11)
    Background: Breast reconstruction is associated with high levels of patient satisfaction. Previous patient satisfaction studies have been subjective. This study utilizes functional magnetic resonance imaging (fMRI) to ...
  • Wang, Fa; Lee, Dung-Hai; Wang, Qiang-Hua; Wang, Wan-Sheng; Xiang, Yuan-Yuan; Yang, Fan (American Physical Society, 2012-01)
    We study the electronic instabilities of near 1/4 electron doped graphene using the singular-mode functional renormalization group, with a self-adaptive k mesh to improve the treatment of the van Hove singularities, and ...
  • Habib, Naomi; Wapinski, Ilan; Margalit, Hanah; Regev, Aviv; Friedman, Nir (Nature Publishing Group, 2012-10)
    Evolutionary rewiring of regulatory networks is an important source of diversity among species. Previous evidence suggested substantial divergence of regulatory networks across species. However, systematically assessing ...
  • Boyle, Elette; Goldwasser, Shafi; Ivan, Ioana (Springer-Verlag Berlin Heidelberg, 2014)
    We introduce two new cryptographic primitives: functional digital signatures and functional pseudorandom functions. In a functional signature scheme, in addition to a master signing key that can be used to sign any ...
  • Fedorenko, Evelina G.; Behr, Michael K.; Kanwisher, Nancy (National Academy of Sciences (U.S.), 2011-09)
    Neuroscientists have debated for centuries whether some regions of the human brain are selectively engaged in specific high-level mental functions or whether, instead, cognition is implemented in multifunctional brain ...
  • Kanwisher, Nancy (National Academy of Sciences (U.S.), 2010-06)
    Is the human mind/brain composed of a set of highly specialized components, each carrying out a specific aspect of human cognition, or is it more of a general-purpose device, in which each component participates in a wide ...
  • Sabuncu, Mert R.; Singer, Benjamin D.; Conroy, Bryan,; Bryan, Ronald E.; Ramadge, Peter J.; Haxby, James V. (Oxford University Press, 2009-05)
    Making conclusions about the functional neuroanatomical organization of the human brain requires methods for relating the functional anatomy of an individual's brain to population variability. We have developed a method ...
  • Rago, Florencia; Cheeseman, Iain McPherson (Rockefeller University Press, The, 2013-03)
    Chromosome segregation requires the generation of force at the kinetochore—the multiprotein structure that facilitates attachment of chromosomes to spindle microtubules. This force is required both to move chromosomes and ...
  • Wehrheim, Katrin; Woodward, Chris T. (European Mathematical Society, 2010-01)
    We associate to every monotone Lagrangian correspondence a functor between Donaldson–Fukaya categories. The composition of such functors agrees with the functor associated to the geometric composition of the correspondences, ...
  • Orr-Weaver, Terry L.; Sher, Noa; Von Stetina, Jessica R.; Bell, George W.; Matsuura, Shinobu; Ravid, Katya (National Academy of Sciences (U.S.), 2013-04)
    Throughout the plant and animal kingdoms specific cell types become polyploid, increasing their DNA content to attain a large cell size. In mammals, megakaryocytes (MKs) become polyploid before fragmenting into platelets. ...
  • Shen, Yuan; Win, Moe Z. (Institute of Electrical and Electronics Engineers, 2010-09)
    The availability of position information is of great importance in many commercial, public safety, and military applications. The coming years will see the emergence of location-aware networks with submeter accuracy, relying ...
  • Shen, Yuan; Wymeersch, Henk; Win, Moe Z. (Institute of Electrical and Electronics Engineers, 2010-09)
    The availability of position information is of great importance in many commercial, governmental, and military applications. Localization is commonly accomplished through the use of radio communication between mobile devices ...
  • Qiu, W.; DeLacy, B. G.; Miller, Owen D.; Hsu, Chia Wei; Reid, M. T. Homer; Joannopoulos, John D.; Soljacic, Marin; Johnson, Steven G. (American Physical Society, 2014-03)
    We show that there are shape-independent upper bounds to the extinction cross section per unit volume of dilute, randomly arranged nanoparticles, given only material permittivity. Underlying the limits are restrictive sum ...
  • Chen, Jian; Sickler, Jason; Byun, Hyunil; Ippen, Erich P.; Jiang, Shibin; Kaertner, Franz X. (Springer Berlin/Heidelberg, 2009)
    Low jitter 500-fs pulse trains at a fundamental repetition rate of 3.2 GHz, from an Erfiber laser with a saturable Bragg reflector. An increase in repetition rate of femtosecond fiberlasers by one order of magnitude.
  • Pavone, Marco; Treleaven, Kyle Ballantyne; Frazzoli, Emilio (Institute of Electrical and Electronics Engineers, 2011-02)
    Transportation-On-Demand (TOD) systems, where users generate requests for transportation from a pick-up point to a delivery point, are already very popular and are expected to increase in usage dramatically as the inconvenience ...
  • Loh, Po-Ru; Oskooi, Ardavan F.; Ibanescu, Mihai; Skorobogatiy, Maksim; Johnson, Steven G. (American Physical Society, 2009-06)
    We demonstrate that the ratio of group to phase velocity has a simple relationship to the orientation of the electromagnetic field. In nondispersive materials, opposite group and phase velocity corresponds to fields that ...
  • Stroock, Daniel W.; Chen, Linan (Society for Industrial and Applied Mathematics, 2010-03)
    The Wright–Fisher equation, which was introduced as a model to study demography in the presence of diffusion, has had a renaissance as a model for the migration of alleles in the genome. Our goal in this paper is to give ...
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