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Browsing MIT Open Access Articles by Title

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  • Blackwell, William J.; Aumann, Hartmut H.; Manning, Evan; Barnet, Chris; Maddy, Eric (The International Society for Optical Engineering, 2009-08)
    With the availability of very accurate six hour forecasts, the metric of accuracy alone for the evaluation of the performance of a retrieval system can produce misleading results: the retrievals may be statistically accurate, ...
  • Bear, James E.; Svitkina, Tatyana M.; Krause, Matthias; Schafer, Dorothy A.; Loureiro, Joseph J.; Strasser, Geraldine A.; Maly, Ivan V.; Chaga, Oleg Y.; Cooper, John A.; Borisy, Gary G.; Gertler, Frank (Elsevier, 2002-05)
    Cell motility requires lamellipodial protrusion, a process driven by actin polymerization. Ena/VASP proteins accumulate in protruding lamellipodia and promote the rapid actin-driven motility of the pathogen Listeria. In ...
  • Death, R.; Wadham, J. L.; Monteiro, F.; Le Brocq, A. M.; Tranter, M.; Ridgwell, A.; Dutkiewicz, Stephanie; Raiswell, R. (Copernicus GmbH on behalf of the European Geosciences Union, 2014-05)
    Southern Ocean (SO) marine primary productivity (PP) is strongly influenced by the availability of iron in surface waters, which is thought to exert a significant control upon atmospheric CO2 concentrations on glacial/interglacial ...
  • Doyle, Keith B. (The International Society for Optical Engineering, 2009-10)
    Antenna performance predictions and calibration times are estimated on a 37 m diameter radio telescope subject to thermal perturbations. The telescope is designed to operate at frequencies up to 325 GHz with a one-way ...
  • Lee, Jong-Mi; Echegoyen, Yolanda; Carrasco, Gonzalo; Zhao, Ning; Zhang, Jing; Gamo, Toshitaka; Obata, Hajime; Norisuye, Kazuhiro; Boyle, Edward A.; Noble, Abigail Emery; Moos, Simone Beatrice; Kayser, Rick (Oceanography Society, 2014-03)
    We review the current distribution of lead and lead isotopes in the ocean with regard to the evolving pattern of human emissions during the past decades and centuries.
  • Martell, Jeffrey Daniel; Takahashi, Noriko; Vercruysse, Maarten; Ting, Alice Y.; Walker, Graham C.; Dwyer, Daniel J.; Belenky, Peter A.; Yang, Jason H.; MacDonald, I. Cody; Chan, Clement T. Y.; Lobritz, Michael A.; Braff, Dana; Schwarz, Eric G.; Ye, Jonathan D.; Pati, Mekhala; Ralifo, Paul S.; Allison, Kyle R.; Khalil, Ahmad S.; Collins, James J. (National Academy of Sciences (U.S.), 2014-05)
    Deeper understanding of antibiotic-induced physiological responses is critical to identifying means for enhancing our current antibiotic arsenal. Bactericidal antibiotics with diverse targets have been hypothesized to kill ...
  • Garrett, Thomas P. J.; Burgess, Anthony W.; Gan, Hui K.; Luwor, Rod B.; Cartwright, Glenn; Walker, Francesca; Orchard, Suzanne G.; Clayton, Andrew H. A.; Nice, Edouard C.; Rothacker, Julie; Catimel, Bruno; Cavenee, Webster K.; Old, Lloyd J.; Stockert, Elisabeth; Ritter, Gerd; Adams, Timothy E.; Hoyne, Peter A.; Wittrup, Karl Dane; Chao, Ginger; Cochran, Jennifer R.; Lou, Cindy; Lou, Mezhen; Huyton, Trevor; Xu, Yibin; Fairlie, W. Douglas; Yao, Shenggen; Scott, Andrew M.; Johns, Terrance G. (National Academy of Sciences, 2009-03)
    Epidermal Growth Factor Receptor (EGFR) is involved in stimulating the growth of many human tumors, but the success of therapeutic agents has been limited in part by interference from the EGFR on normal tissues. Previously, ...
  • Mittal, Sukant; Wong, Ian Y.; Deen, William M.; Toner, Mehmet; Deen, William M. (Elsevier, 2012-02)
    Adhesion-based cell capture on surfaces in microfluidic devices forms the basis of numerous biomedical diagnostics and in vitro assays. However, the performance of these platforms is partly limited by interfacial phenomena ...
  • Rhodes, Donna H.; Ross, Adam Michael (Institute of Electrical and Electronics Engineers, 2009-05)
    The paper presents a vision for enhancing anticipatory capacity of engineering organizations, with a goal of enabling the design of systems that can deliver sustained value as the world changes. Anticipatory capacity is ...
  • Haggarty, Stephen J.; Covington III, Herbert E.; Maze, Ian; LaPlant, Quincey C.; Vialou, Vincent F.; Ohnishi, Yoshinori N.; Berton, Olivier; Fass, Dan M.; Renthal, William; Rush III, Augustus J.; Wu, Emma Y.; Ghose, Subroto; Krishnan, Vaishnav; Russo, Scott J.; Tamminga, Carol; Nestler, Eric J. (Society for Neuroscience, 2009-07)
    Persistent symptoms of depression suggest the involvement of stable molecular adaptations in brain, which may be reflected at the level of chromatin remodeling. We find that chronic social defeat stress in mice causes a ...
  • Covington III, Herbert E.; Lobo, Mary Kay; Maze, Ian; Vialou, Vincent; Hyman, James M.; Zaman, Samir; LaPlant, Quincey; Mouzon, Ezekiel; Ghose, Subroto; Tamminga, Carol A.; Neve, Rachael L.; Deisseroth, Karl; Nestler, Eric J. (Society for Neuroscience, 2010-09)
    Brain stimulation and imaging studies in humans have highlighted a key role for the prefrontal cortex in clinical depression; however, it remains unknown whether excitation or inhibition of prefrontal cortical neuronal ...
  • Roland, Christof E.; Roland, Gunther M. (American Physical Society, 2012-04)
    Production of deuterons and antideuterons was studied by the NA49 experiment in the 23.5% most central Pb+Pb collisions at the top CERN Super Proton Synchroton (SPS) energy of √s[subscript NN]=17.3 GeV. Invariant yields ...
  • Cowan, Ray Franklin; Sciolla, Gabriella (American Physical Society, 2014-06)
    We present measurements of the inclusive production of antideuterons in e[superscript +]e[superscript −] annihilation into hadrons at ≈ 10.58  GeV center-of-mass energy and in Υ(1S,2S,3S) decays. The results are obtained ...
  • Shen, Ching-Hung; Talay, Oezcan; Mahajan, Vinay S.; Leskov, Ilya; Eisen, Herman N.; Chen, Jianzhu (National Academy of Sciences (U.S.), 2010-12)
    Memory T cells of the effector type (TEM) account for the characteristic rapidity of memory T-cell responses, whereas memory T cells of the central type (TCM) account for long-lasting, vigorously proliferating memory T-cell ...
  • Moon, James J.; Suh, Heikyung; Polhemus, Mark E.; Ockenhouse, Christian F.; Yadava, Anjali; Irvine, Darrell J. (Public Library of Science, 2012-02)
    The parasite Plasmodium vivax is the most frequent cause of malaria outside of sub-Saharan Africa, but efforts to develop viable vaccines against P. vivax so far have been inadequate. We recently developed pathogen-mimicking ...
  • Tharakaraman, Kannan; Raman, Rahul; Stebbins, Nathan W.; Viswanathan, Karthik; Sasisekharan, Viswanathan; Sasisekharan, Ram (Nature Publishing Group, 2013-05)
    The 2009 swine-origin H1N1 influenza, though antigenically novel to the population at the time, was antigenically similar to the 1918 H1N1 pandemic influenza, and consequently was considered to be “archived” in the swine ...
  • Fiamegos, Yiannis C.; Kastritis, Panagiotis L.; Exarchou, Vassiliki; Han, Haley; Bonvin, Alexandre M. J. J.; Vervoort, Jacques; Lewis, Kim; Hamblin, Michael R.; Tegos, George P. (Public Library of Science, 2011-04)
    Background: Traditional antibiotics are increasingly suffering from the emergence of multidrug resistance amongst pathogenic bacteria leading to a range of novel approaches to control microbial infections being investigated ...
  • Shukla, A.; Stephanopoulos, Gregory; Hammond, Paula T. (Institute of Electrical and Electronics Engineers, 2009-05)
    The overuse of antibiotics has led to a rise in antibiotic resistance of common hospital dwelling bacteria such as Staphylococcus aureus. Novel broad-spectrum antimicrobials that operate without further contributing to a ...
  • Chakraborty, Rupak; Buonassisi, Tonio; Sinsermsuksakul, Prasert; Kim, Sang Bok; Heald, Steven M.; Gordon, Roy G. (American Chemical Society (ACS), 2012-11)
    Thin-film solar cells made from earth-abundant, inexpensive, and nontoxic materials are needed to replace the current technologies whose widespread use is limited by their use of scarce, costly, and toxic elements. Tin ...
  • Almotahari, Mahrad (MIT Press, 2011-07)
    Standard theories of so-called donkey anaphora (Kamp 1981, Heim 1982, Groenendijk and Stokhof 1991) predict that sentence (1) is truth conditionally equivalent to (2). (1) Every farmer who owns a donkey beats it. (2) ...
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